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Aliases for PLEKHF1 Gene
Aliases for PLEKHF1 Gene
- Pleckstrin Homology And FYVE Domain Containing 1 2 3 5
- ZFYVE15 2 3 4
- APPD 2 3 4
- Lysosome-Associated Apoptosis-Inducing Protein Containing PH And FYVE Domains 3 4
- Pleckstrin Homology Domain Containing, Family F (With FYVE Domain) Member 1 2 3
- Pleckstrin Homology Domain-Containing Family F Member 1 3 4
- Zinc Finger FYVE Domain-Containing Protein 15 3 4
- PH And FYVE Domain-Containing Protein 1 3 4
External Ids for PLEKHF1 Gene
- HGNC: 20764
- Entrez Gene: 79156
- Ensembl: ENSG00000166289
- OMIM: 615200
- UniProtKB: Q96S99
Previous GeneCards Identifiers for PLEKHF1 Gene
- GC19P030604
- GC19P034832
- GC19P034847
- GC19P030155
- GC19P026668
Summaries for PLEKHF1 Gene
GeneCards Summary for PLEKHF1 Gene
PLEKHF1 (Pleckstrin Homology And FYVE Domain Containing 1) is a Protein Coding gene. Diseases associated with PLEKHF1 include 46,Xy Sex Reversal 8 and Congenital Anomalies Of Kidney And Urinary Tract 2. Gene Ontology (GO) annotations related to this gene include phosphatidylinositol-3-phosphate binding and phosphatidylinositol-5-phosphate binding. An important paralog of this gene is PLEKHF2.
UniProtKB/Swiss-Prot Summary for PLEKHF1 Gene
-
May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Additional gene information for PLEKHF1 Gene
- HGNC(20764)
- Entrez Gene(79156)
- Ensembl(ENSG00000166289)
- OMIM(615200)
- UniProtKB(Q96S99)
- Open Targets Platform(ENSG00000166289)
- Monarch Initiative
- Search for PLEKHF1 at DataMed
- Search for PLEKHF1 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PLEKHF1 Gene
Genomics for PLEKHF1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for PLEKHF1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around PLEKHF1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PLEKHF1
- Top Transcription factor binding sites by QIAGEN in the PLEKHF1 gene promoter:
-
- ATF-2
- c-Fos
- c-Jun
- CRE-BP1
- Evi-1
- HSF1 (long)
- HSF1short
- MyoD
- Nkx5-1
- PPAR-alpha
Genomic Locations for PLEKHF1 Gene
Genomic Locations for PLEKHF1 Gene
- chr19:29,665,422-29,675,477
- (GRCh38/hg38)
- Size:
- 10,056 bases
- Orientation:
- Plus strand
- chr19:30,155,963-30,166,384
- (GRCh37/hg19)
- Size:
- 10,422 bases
- Orientation:
- Plus strand
Genomic View for PLEKHF1 Gene
Genes around PLEKHF1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q12 by HGNC
- 19q12 by Entrez Gene
- 19q12 by Ensembl
PLEKHF1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PLEKHF1 Gene
Proteins for PLEKHF1 Gene
-
Protein details for PLEKHF1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96S99-PKHF1_HUMAN
- Recommended name:
- Pleckstrin homology domain-containing family F member 1
- Protein Accession:
- Q96S99
- Q96K11
- Q9BUB9
Protein attributes for PLEKHF1 Gene
- Size:
- 279 amino acids
- Molecular mass:
- 31195 Da
- Quaternary structure:
- No Data Available
Protein Expression for PLEKHF1 Gene
Post-translational modifications for PLEKHF1 Gene
Other Protein References for PLEKHF1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for PLEKHF1
- Novus Biologicals Antibodies for PLEKHF1
- Invitrogen Antibodies for PLEKHF1 (AFLGC-PLEKHF1)
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for PLEKHF1
- Origene Custom Protein Services for PLEKHF1
- antibodies-online: Show 3 available PLEKHF1 Proteins ranked by validation data
- Compare Top PLEKHF1 Proteins
-
Quality Products:
No data available for DME Specific Peptides for PLEKHF1 Gene
Domains & Families for PLEKHF1 Gene
Gene Families for PLEKHF1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PLEKHF1 Gene
- InterPro:
- Blocks:
-
- Pleckstrin-like
- Zn-finger, FYVE type
- ProtoNet:
Suggested Antigen Peptide Sequences for PLEKHF1 Gene
- GenScript: Design optimal peptide antigens:
-
- Zinc finger FYVE domain-containing protein 15 (PKHF1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96S99UniProtKB/Swiss-Prot:
PKHF1_HUMAN :- PH and FYVE-type zinc finger domains are required for lysosomal location.
- Domain:
-
- PH and FYVE-type zinc finger domains are required for lysosomal location.
Function for PLEKHF1 Gene
Molecular function for PLEKHF1 Gene
- UniProtKB/Swiss-Prot Function:
- May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Phenotypes From GWAS Catalog for PLEKHF1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0010314 | phosphatidylinositol-5-phosphate binding | IDA | 22115783 |
| GO:0032266 | phosphatidylinositol-3-phosphate binding | IDA | 22115783 |
| GO:0035091 | phosphatidylinositol binding | IBA | 21873635 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for PLEKHF1 Gene
- MGI mutant phenotypes for PLEKHF1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for PLEKHF1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PLEKHF1 - Select products 50% OFF >
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-
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-
Santa Cruz Biotechnology (SCBT) CRISPR for PLEKHF1
miRNA for PLEKHF1 Gene
- miRTarBase miRNAs that target PLEKHF1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PLEKHF1
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Clone Products
- Applied Biological Materials (abm): Clones for PLEKHF1 - Select products 50% OFF >
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- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PLEKHF1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PLEKHF1
Cell Line Products
-
Horizon Cell Lines for PLEKHF1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PLEKHF1 Gene
Localization for PLEKHF1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PLEKHF1 Gene
- Nucleus. Cytoplasm, perinuclear region. Lysosome. Note=Translocates to lysosome during apoptosis.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| endosome | 4 |
| lysosome | 4 |
| cytosol | 3 |
| extracellular | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005764 | lysosome | IDA | 22115783 |
| GO:0005765 | lysosomal membrane | IC | 22115783 |
| GO:0005768 | colocalizes_with endosome | IDA | 22115783 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for PLEKHF1 Gene
Pathways & Interactions for PLEKHF1 Gene
Interacting Proteins for PLEKHF1 Gene
Selected Interacting proteins:
Q96S99-PKHF1_HUMAN
ENSP00000389787
for PLEKHF1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for PLEKHF1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0007032 | endosome organization | IMP | 22115783 |
| GO:0010508 | positive regulation of autophagy | IDA | 22115783 |
| GO:0016050 | vesicle organization | IMP | 22115783 |
| GO:0072659 | protein localization to plasma membrane | IMP | 22115783 |
No data available for Pathways by source and SIGNOR curated interactions for PLEKHF1 Gene
Transcripts for PLEKHF1 Gene
mRNA/cDNA for PLEKHF1 Gene
- 1 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000436066 1699 nts (view in UCSC)
- ENST00000586888 707 nts (view in UCSC)
- ENST00000588833 543 nts (view in UCSC)
- ENST00000592810 1357 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PLEKHF1 - Select products 50% OFF >
- * PLEKHF1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PLEKHF1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PLEKHF1
-
Santa Cruz Biotechnology (SCBT) CRISPR for PLEKHF1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PLEKHF1
- Browse OriGene Inhibitory RNA Products For PLEKHF1
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Clone Products
- Applied Biological Materials (abm): Clones for PLEKHF1 - Select products 50% OFF >
- * PLEKHF1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PLEKHF1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PLEKHF1
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||
| SP2: | - | ||||||||||||||||||
| SP3: | - | - | |||||||||||||||||
| SP4: |
Relevant External Links for PLEKHF1 Gene
- GeneLoc Exon Structure for
- PLEKHF1
Expression for PLEKHF1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Glial Cells
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Eye (Sensory Organs)
- AII Amacrine Cells Inner Nuclear Layer
-
Neurons
- AII Amacrine Cells Inner Nuclear Layer
-
Blood (Hematopoietic System)
- Natural Killer Cells Peripheral Blood
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for PLEKHF1 Gene
This gene is overexpressed in Muscle - Skeletal (x6.0).
This gene is overexpressed in NK cells (29.2) and CD8 Tcells (9.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PLEKHF1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PLEKHF1
SOURCE GeneReport for Unigene cluster for PLEKHF1 Gene:
Hs.466383mRNA Expression by UniProt/SwissProt for PLEKHF1 Gene:
Q96S99-PKHF1_HUMAN
Tissue specificity:
Highly expressed in heart and skeletal muscle. Weakly expressed in brain, thymus, spleen, kidney, liver, small intestine, placenta and lung.
Evidence on tissue expression from TISSUES for PLEKHF1 Gene
- Nervous system(4.4)
- Muscle(2.6)
- Blood(2)
Primer Products
-
OriGene qPCR primer pairs for PLEKHF1
-
OriGene qPCR primer pairs and template standards for PLEKHF1
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for PLEKHF1 Gene
Orthologs for PLEKHF1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | PLEKHF1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | bta-mir-2901 31 |
|
OneToOne | |
| PLEKHF1 30 |
|
||||
| Dog (Canis familiaris) |
Mammalia | PLEKHF1 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Plekhf1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Plekhf1 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | PLEKHF1 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | PLEKHF1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | PLEKHF1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | PLEKHF1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | plekhf1 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | plekhf1 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | RhoGEF4 31 |
|
ManyToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | tag-52 31 |
|
ManyToMany |
- Species where no ortholog for PLEKHF1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for PLEKHF1 Gene
- ENSEMBL:
- Gene Tree for PLEKHF1 (if available)
- TreeFam:
- Gene Tree for PLEKHF1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PLEKHF1: view image
Paralogs for PLEKHF1 Gene
Paralogs for PLEKHF1 Gene
(2) SIMAP similar genes for PLEKHF1 Gene using alignment to 3 proteins:
- PKHF1_HUMAN
- K7EIX0_HUMAN
- K7ELB8_HUMAN
Variants for PLEKHF1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PLEKHF1 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 711219 | Benign: not provided | 29,674,486(+) | G/A | MISSENSE_VARIANT | |
| 727604 | Likely Benign: not provided | 29,674,562(+) | G/T | SYNONYMOUS_VARIANT | |
| 730019 | Benign: not provided | 29,674,083(+) | C/T | SYNONYMOUS_VARIANT | |
| 769452 | Benign: not provided | 29,673,890(+) | A/G | SYNONYMOUS_VARIANT | |
| 777467 | Benign: not provided | 29,674,277(+) | G/A | SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1061174 | CNV | gain | 25217958 |
| nsv1061604 | CNV | loss | 25217958 |
| nsv833799 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
76.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.16;
23.35% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PLEKHF1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PLEKHF1 Gene
Disorders for PLEKHF1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| 46,xy sex reversal 8 |
|
|
| congenital anomalies of kidney and urinary tract 2 |
|
|
| prune belly syndrome |
|
|
| capillary malformations, congenital |
|
|
| vesicoureteral reflux 1 |
|
|
Search PLEKHF1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for PLEKHF1
No data available for UniProtKB/Swiss-Prot and Genatlas for PLEKHF1 Gene
Publications for PLEKHF1 Gene
- The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway. (PMID: 16188880) Chen W … Cao X (The Journal of biological chemistry 2005) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3
ExternalLinks
Products for PLEKHF1 Gene
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- Novus Biologicals Antibodies for PLEKHF1
- Novus Biologicals proteins and lysates for PLEKHF1
- Browse Antibodies
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- Invitrogen Antibodies for PLEKHF1 (AFLGC-PLEKHF1)
- VectorBuilder Custom and pre-made DNA vectors for PLEKHF1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for PLEKHF1 (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Stable cell line generation for PLEKHF1
- antibodies-online: Show 14 available PLEKHF1 Antibodies ranked by validation data
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- antibodies-online: Search results for available PLEKHF1 related products ranked by validation data
- antibodies-online: Show 3 available PLEKHF1 Proteins ranked by validation data
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- Quality Products:
- Horizon Cell Lines for PLEKHF1
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for PLEKHF1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PLEKHF1
Sources for PLEKHF1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
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