Aliases for PLEKHA8P1 Gene

Aliases for PLEKHA8P1 Gene

  • Pleckstrin Homology Domain Containing A8 Pseudogene 1 2 3 5
  • Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 9 2 3
  • Pleckstrin Homology Domain Containing, Family A Member 8 Pseudogene 1 2 3
  • Putative Glycolipid Transfer Protein 2 3
  • PLEKHA9 3 4
  • Pleckstrin Homology Domain-Containing Family A Member 8 Pseudogene 1 4
  • Pleckstrin Homology Domain-Containing Family A Member 8 3
  • Phosphatidylinositol-Four-Phosphate Adapter Protein 2 3
  • Serologically Defined Breast Cancer Antigen NY-BR-86 3
  • Phosphoinositol 4-Phosphate Adapter Protein 2 3
  • PH Domain-Containing Family A Member 8 3
  • Putative Protein PLEKHA9 4
  • PLEKHA8 3
  • FAPP-2 3
  • HFAPP2 3
  • FAPP2 3

External Ids for PLEKHA8P1 Gene

Previous HGNC Symbols for PLEKHA8P1 Gene

  • PLEKHA9

Previous GeneCards Identifiers for PLEKHA8P1 Gene

  • GC12M045567
  • GC12M045571

Summaries for PLEKHA8P1 Gene

GeneCards Summary for PLEKHA8P1 Gene

PLEKHA8P1 (Pleckstrin Homology Domain Containing A8 Pseudogene 1) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include glycolipid binding and glycolipid transporter activity.

Additional gene information for PLEKHA8P1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PLEKHA8P1 Gene

Genomics for PLEKHA8P1 Gene

GeneHancer (GH) Regulatory Elements for PLEKHA8P1 Gene

Promoters and enhancers for PLEKHA8P1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J045214 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 500.7 -1.9 -1855 7.4 ZNF217 CTCF ZSCAN5C NRF1 TCF12 USF1 POLR2G PHF8 ZFX ZNF639 ANO6 PLEKHA8P1 lnc-DBX2-4 SCAF11 ARID2 ENSG00000278351
GH12J045189 Enhancer 1.2 Ensembl ENCODE dbSUPER 12.3 +24.7 24740 4.6 HNRNPK TCF12 NCOR1 JUND FOS TCF7 CTBP1 JUN TEAD1 OSR2 ANO6 PLEKHA8P1 DBX2 piR-38580-060 ENSG00000257738 lnc-ANO6-3 lnc-DBX2-4
GH12J045258 Enhancer 1.1 ENCODE dbSUPER 12.1 -43.8 -43810 2.6 POLR2G NCOR1 KDM6A TCF7 CUX1 ZBTB25 EP300 CTBP1 SKI TEAD1 PLEKHA8P1 ANO6 ENSG00000278351 piR-33432-116
GH12J045296 Enhancer 1.2 Ensembl ENCODE dbSUPER 11.1 -82.2 -82160 4.4 ZNF217 ZSCAN5C HES1 CTBP1 FOXA2 NCOR1 ELK1 NFIC IRF1 CEBPB ANO6 PLEKHA8P1 ENSG00000278351 piR-33432-116
GH12J045257 Promoter/Enhancer 1 Ensembl dbSUPER 11.8 -41.3 -41260 0.2 CTBP1 NBN EHMT2 EBF1 IKZF1 CTCF MAZ HDGF TBX21 POLR2A ENSG00000278351 PLEKHA8P1 ANO6 piR-33432-116
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PLEKHA8P1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for PLEKHA8P1 Gene

Genomic Locations for PLEKHA8P1 Gene
chr12:45,173,034-45,216,041
(GRCh38/hg38)
Size:
43,008 bases
Orientation:
Minus strand
chr12:45,566,817-45,609,824
(GRCh37/hg19)
Size:
43,008 bases
Orientation:
Minus strand

Genomic View for PLEKHA8P1 Gene

Genes around PLEKHA8P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PLEKHA8P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PLEKHA8P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PLEKHA8P1 Gene

Proteins for PLEKHA8P1 Gene

  • Protein details for PLEKHA8P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95397-PKHA9_HUMAN
    Recommended name:
    Putative protein PLEKHA9
    Protein Accession:
    O95397

    Protein attributes for PLEKHA8P1 Gene

    Size:
    391 amino acids
    Molecular mass:
    43539 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PLEKHA8P1 Gene

Post-translational modifications for PLEKHA8P1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for PLEKHA8P1 Gene

Domains & Families for PLEKHA8P1 Gene

Protein Domains for PLEKHA8P1 Gene

Suggested Antigen Peptide Sequences for PLEKHA8P1 Gene

GenScript: Design optimal peptide antigens:
  • Pleckstrin homology domain-containing family A member 8 pseudogene 1 (PKHA9_HUMAN)
genes like me logo Genes that share domains with PLEKHA8P1: view

No data available for Gene Families , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PLEKHA8P1 Gene

Function for PLEKHA8P1 Gene

Phenotypes From GWAS Catalog for PLEKHA8P1 Gene

Gene Ontology (GO) - Molecular Function for PLEKHA8P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008289 lipid binding IBA 21873635
GO:1902387 ceramide 1-phosphate binding IBA 21873635
GO:1902388 ceramide 1-phosphate transporter activity IBA 21873635
genes like me logo Genes that share ontologies with PLEKHA8P1: view
genes like me logo Genes that share phenotypes with PLEKHA8P1: view

Animal Model Products

CRISPR Products

miRNA for PLEKHA8P1 Gene

miRTarBase miRNAs that target PLEKHA8P1

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PLEKHA8P1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PLEKHA8P1 Gene

Localization for PLEKHA8P1 Gene

Gene Ontology (GO) - Cellular Components for PLEKHA8P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol IBA 21873635
genes like me logo Genes that share ontologies with PLEKHA8P1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for PLEKHA8P1 Gene

Pathways & Interactions for PLEKHA8P1 Gene

PathCards logo

SuperPathways for PLEKHA8P1 Gene

No Data Available

Interacting Proteins for PLEKHA8P1 Gene

Selected Interacting proteins: O95397-PKHA9_HUMAN for PLEKHA8P1 Gene via IID

;

Gene Ontology (GO) - Biological Process for PLEKHA8P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035621 ER to Golgi ceramide transport IBA 21873635
GO:0035627 ceramide transport IBA 21873635
GO:0120009 intermembrane lipid transfer IBA 21873635
GO:1902389 ceramide 1-phosphate transport IEA --
genes like me logo Genes that share ontologies with PLEKHA8P1: view

No data available for Pathways by source and SIGNOR curated interactions for PLEKHA8P1 Gene

Drugs & Compounds for PLEKHA8P1 Gene

(4) Drugs for PLEKHA8P1 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phytosphingosine Experimental Pharma 0
Sphingosine Experimental Pharma 0
sphinganine Pharma 0
Sphingosine-1-phosphate Pharma Full agonist, Agonist endogenous second messenger and ligand for S1PR1, Endogenous agonist at S1P1-5 0

(514) Additional Compounds for PLEKHA8P1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
3-Dehydrosphinganine
  • 3-dehydro-D-Sphinganine
  • 3-Ketodihydrosphingosine
  • 3-Ketosphinganine
  • (2S)-2-amino-1-Hydroxyoctadecan-3-one
  • 1-Hydroxy-2-amino-3-oxo-octadecane
16105-69-4
3-O-Sulfogalactosylceramide (d18:1/12:0)
  • 3'-O-Sulphogalactosylceramide
  • 3-O-SulfO-beta-D-galactosylceramide
  • 3-O-SulfO-beta-delta-galactosylceramide
  • 3-O-Sulfogalactosylceramide
  • Cerebroside 3-sulfate
852100-88-0
3-O-Sulfogalactosylceramide (d18:1/14:0)
  • 3'-O-Sulphogalactosylceramide
  • 3-O-SulfO-beta-D-galactosylceramide
  • 3-O-SulfO-beta-delta-galactosylceramide
  • 3-O-Sulfogalactosylceramide
  • Cerebroside 3-sulfate
3-O-Sulfogalactosylceramide (d18:1/16:0)
  • 3'-O-Sulphogalactosylceramide
  • 3-O-SulfO-beta-D-galactosylceramide
  • 3-O-SulfO-beta-delta-galactosylceramide
  • 3-O-Sulfogalactosylceramide
  • Cerebroside 3-sulfate
862509-48-6
3-O-Sulfogalactosylceramide (d18:1/18:0)
  • 3'-O-Sulphogalactosylceramide
  • 3-O-SulfO-beta-D-galactosylceramide
  • 3-O-SulfO-beta-delta-galactosylceramide
  • 3-O-Sulfogalactosylceramide
  • Cerebroside 3-sulfate
244215-65-4
genes like me logo Genes that share compounds with PLEKHA8P1: view

Transcripts for PLEKHA8P1 Gene

mRNA/cDNA for PLEKHA8P1 Gene

1 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PLEKHA8P1

Alternative Splicing Database (ASD) splice patterns (SP) for PLEKHA8P1 Gene

No ASD Table

Relevant External Links for PLEKHA8P1 Gene

GeneLoc Exon Structure for
PLEKHA8P1

Expression for PLEKHA8P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PLEKHA8P1 Gene

Protein differential expression in normal tissues from HIPED for PLEKHA8P1 Gene

This gene is overexpressed in Plasma (62.1) and Platelet (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PLEKHA8P1 Gene



Protein tissue co-expression partners for PLEKHA8P1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PLEKHA8P1

SOURCE GeneReport for Unigene cluster for PLEKHA8P1 Gene:

Hs.558495
genes like me logo Genes that share expression patterns with PLEKHA8P1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PLEKHA8P1 Gene

Orthologs for PLEKHA8P1 Gene

Evolution for PLEKHA8P1 Gene

ENSEMBL:
Gene Tree for PLEKHA8P1 (if available)
TreeFam:
Gene Tree for PLEKHA8P1 (if available)

No data available for Orthologs for PLEKHA8P1 Gene

Paralogs for PLEKHA8P1 Gene

(1) SIMAP similar genes for PLEKHA8P1 Gene using alignment to 1 proteins:

  • PKHA9_HUMAN
genes like me logo Genes that share paralogs with PLEKHA8P1: view

No data available for Paralogs for PLEKHA8P1 Gene

Variants for PLEKHA8P1 Gene

Structural Variations from Database of Genomic Variants (DGV) for PLEKHA8P1 Gene

Variant ID Type Subtype PubMed ID
esv3580255 CNV loss 25503493
nsv1051285 CNV loss 25217958
nsv689 CNV insertion 18451855
nsv973060 CNV duplication 23825009

Additional Variant Information for PLEKHA8P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PLEKHA8P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for PLEKHA8P1 Gene

Disorders for PLEKHA8P1 Gene

Additional Disease Information for PLEKHA8P1

No disorders were found for PLEKHA8P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PLEKHA8P1 Gene

Publications for PLEKHA8P1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 54
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 54
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 54
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3 54

Products for PLEKHA8P1 Gene

Sources for PLEKHA8P1 Gene