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PLEKHA6 (Pleckstrin Homology Domain Containing A6) is a Protein Coding gene. Among its related pathways are PI Metabolism and Metabolism. An important paralog of this gene is PLEKHA7.
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Metabolism |
.40
|
|
2 | PI Metabolism |
.63
|
|
3 | Glycerophospholipid biosynthesis |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | PLEKHA6 33 32 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | PLEKHA6 33 32 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | PLEKHA6 33 |
|
OneToOne | |
mouse (Mus musculus) |
Mammalia | Plekha6 33 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | PLEKHA6 33 |
|
OneToOne | |
oppossum (Monodelphis domestica) |
Mammalia | PLEKHA6 33 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | PLEKHA6 33 |
|
OneToOne | |
lizard (Anolis carolinensis) |
Reptilia | PLEKHA6 33 |
|
OneToOne | |
zebrafish (Danio rerio) |
Actinopterygii | PLEKHA6 33 |
|
OneToOne | |
fruit fly (Drosophila melanogaster) |
Insecta | CG34383 33 |
|
OneToMany | |
sea squirt (Ciona savignyi) |
Ascidiacea | -- 33 |
|
OneToOne |
SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000003862 | -- | 204,302,827(-) | T/C | genic_upstream_transcript_variant, intron_variant | |
rs1000019186 | -- | 204,302,289(-) | A/C | genic_upstream_transcript_variant, intron_variant | |
rs1000027982 | -- | 204,264,549(-) | A/C | 5_prime_UTR_variant, intron_variant | |
rs1000036931 | -- | 204,349,505(-) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
rs1000052285 | -- | 204,345,028(-) | T/C | genic_upstream_transcript_variant, intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2449168 | CNV | insertion | 19546169 |
esv2659081 | CNV | deletion | 23128226 |
esv2666096 | CNV | deletion | 23128226 |
esv2762138 | CNV | gain | 21179565 |
esv3210 | CNV | loss | 18987735 |
esv3356911 | CNV | insertion | 20981092 |
esv3357110 | CNV | insertion | 20981092 |
esv3357869 | CNV | duplication | 20981092 |
esv3578382 | CNV | loss | 25503493 |
esv3588614 | CNV | gain | 21293372 |
esv3588615 | CNV | gain | 21293372 |
esv3588617 | CNV | loss | 21293372 |
esv6345 | CNV | loss | 19470904 |
nsv549039 | CNV | gain | 21841781 |
nsv818778 | CNV | gain | 17921354 |
nsv820074 | CNV | gain | 19587683 |
nsv946604 | CNV | duplication | 23825009 |
No disorders were found for PLEKHA6 Gene.