Free for academic non-profit institutions. Other users need a Commercial license
PLEKHA6 (Pleckstrin Homology Domain Containing A6) is a Protein Coding gene. Diseases associated with PLEKHA6 include Congenital Mesoblastic Nephroma. Among its related pathways are PI Metabolism and Metabolism. An important paralog of this gene is PLEKHA7.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Metabolism |
.40
|
|
2 | PI Metabolism |
.63
|
|
3 | Glycerophospholipid biosynthesis |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | PLEKHA6 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | PLEKHA6 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | PLEKHA6 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Plekha6 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | PLEKHA6 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | PLEKHA6 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | PLEKHA6 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | PLEKHA6 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | PLEKHA6 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | CG34383 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs10900562 | - | p.Arg837Lys | |||
rs10900571 | - | p.Val43Ile |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2449168 | CNV | insertion | 19546169 |
esv2659081 | CNV | deletion | 23128226 |
esv2666096 | CNV | deletion | 23128226 |
esv2762138 | CNV | gain | 21179565 |
esv3210 | CNV | loss | 18987735 |
esv3356911 | CNV | insertion | 20981092 |
esv3357110 | CNV | insertion | 20981092 |
esv3357869 | CNV | duplication | 20981092 |
esv3578382 | CNV | loss | 25503493 |
esv3588614 | CNV | gain | 21293372 |
esv3588615 | CNV | gain | 21293372 |
esv3588617 | CNV | loss | 21293372 |
esv6345 | CNV | loss | 19470904 |
nsv549039 | CNV | gain | 21841781 |
nsv818778 | CNV | gain | 17921354 |
nsv820074 | CNV | gain | 19587683 |
nsv946604 | CNV | duplication | 23825009 |
Disorder | Aliases | PubMed IDs |
---|---|---|
congenital mesoblastic nephroma |
|
|