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PLAAT3 (Phospholipase A And Acyltransferase 3) is a Protein Coding gene. Diseases associated with PLAAT3 include Poland Syndrome. Among its related pathways are Ras signaling pathway and Acyl chain remodelling of PE. An important paralog of this gene is PLAAT2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004623 | phospholipase A2 activity | IBA,IDA | 19047760 |
GO:0005515 | protein binding | IPI | 16189514 |
GO:0008970 | phospholipase A1 activity | IBA,IDA | 19047760 |
GO:0016410 | N-acyltransferase activity | IDA | 22825852 |
GO:0016740 | transferase activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005575 | cellular_component | ND | -- |
GO:0005737 | cytoplasm | IBA | 21873635 |
GO:0005777 | peroxisome | ISS | -- |
GO:0005778 | peroxisomal membrane | IEA | -- |
GO:0005783 | endoplasmic reticulum | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Acyl chain remodelling of PE | ||
2 | Glycerophospholipid biosynthesis | ||
3 | Linoleic acid metabolism | ||
4 | Metabolism |
.40
|
|
5 | Ras signaling pathway |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006629 | lipid metabolic process | IEA | -- |
GO:0006641 | triglyceride metabolic process | ISS | -- |
GO:0006644 | phospholipid metabolic process | IDA | 20100577 |
GO:0007031 | peroxisome organization | ISS | -- |
GO:0008654 | phospholipid biosynthetic process | IEA | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | PLA2G16 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | LOC476045 30 |
|
||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
Cow (Bos Taurus) |
Mammalia | PLA2G16 30 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Mouse (Mus musculus) |
Mammalia | Pla2g16 30 31 |
|
OneToOne | |
Plaat3 17 |
|
||||
Rat (Rattus norvegicus) |
Mammalia | Pla2g16 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
Zebrafish (Danio rerio) |
Actinopterygii | si:ch211-229n2.6 31 |
|
ManyToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv32927 | CNV | gain | 17666407 |
esv33275 | CNV | loss | 17666407 |
esv3626646 | CNV | gain | 21293372 |
esv3626647 | CNV | gain | 21293372 |
nsv1138041 | CNV | deletion | 24896259 |
nsv352 | CNV | insertion | 18451855 |
nsv472513 | CNV | novel sequence insertion | 20440878 |
Disorder | Aliases | PubMed IDs |
---|---|---|
poland syndrome |
|
|