Aliases for PLA2G4F Gene
External Ids for PLA2G4F Gene
Previous GeneCards Identifiers for PLA2G4F Gene
GeneCards Summary for PLA2G4F Gene
PLA2G4F (Phospholipase A2 Group IVF) is a Protein Coding gene. Diseases associated with PLA2G4F include Ileocolitis and Inflammatory Bowel Disease 9. Among its related pathways are Sweet Taste Signaling and Acyl chain remodelling of PE. Gene Ontology (GO) annotations related to this gene include phospholipase A2 activity and lysophospholipase activity. An important paralog of this gene is JMJD7-PLA2G4B.
UniProtKB/Swiss-Prot Summary for PLA2G4F Gene
Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has higher enzyme activity for phosphatidylethanolamine than phosphatidylcholine (By similarity).
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic molecules. There are four major classes; phospholipase A, phospholipase B, phosphoinositide-specific phospholipase C and phospholipase D.