Aliases for PLA2G4E Gene
External Ids for PLA2G4E Gene
Previous GeneCards Identifiers for PLA2G4E Gene
This gene encodes a member of the cytosolic phospholipase A2 group IV family. Members of this family are involved in regulation of membrane tubule-mediated transport. The enzyme encoded by this member of the family plays a role in trafficking through the clathrin-independent endocytic pathway. The enzyme regulates the recycling process via formation of tubules that transport internalized clathrin-independent cargo proteins back to the cell surface. [provided by RefSeq, Jan 2017]
GeneCards Summary for PLA2G4E Gene
PLA2G4E (Phospholipase A2 Group IVE) is a Protein Coding gene. Among its related pathways are Ovarian steroidogenesis and Metabolism. Gene Ontology (GO) annotations related to this gene include phospholipase A2 activity and phospholipase activity. An important paralog of this gene is PLA2G4D.
UniProtKB/Swiss-Prot for PLA2G4E Gene
Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position.
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic molecules. There are four major classes; phospholipase A, phospholipase B, phosphoinositide-specific phospholipase C and phospholipase D.