Aliases for PLA2G2E Gene
External Ids for PLA2G2E Gene
Previous GeneCards Identifiers for PLA2G2E Gene
GeneCards Summary for PLA2G2E Gene
PLA2G2E (Phospholipase A2 Group IIE) is a Protein Coding gene. Among its related pathways are Glycerophospholipid biosynthesis and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include calcium ion binding and phospholipase A2 activity. An important paralog of this gene is PLA2G2A.
UniProtKB/Swiss-Prot for PLA2G2E Gene
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids.
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic molecules. There are four major classes; phospholipase A, phospholipase B, phosphoinositide-specific phospholipase C and phospholipase D.