Aliases for PKNOX1 Gene
External Ids for PKNOX1 Gene
Previous GeneCards Identifiers for PKNOX1 Gene
GeneCards Summary for PKNOX1 Gene
PKNOX1 (PBX/Knotted 1 Homeobox 1) is a Protein Coding gene. Diseases associated with PKNOX1 include Down Syndrome. Among its related pathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and DAG and IP3 signaling. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and protein heterodimerization activity. An important paralog of this gene is PKNOX2.
UniProtKB/Swiss-Prot Summary for PKNOX1 Gene
Activates transcription in the presence of PBX1A and HOXA1.