Aliases for PKIG Gene
External Ids for PKIG Gene
Previous GeneCards Identifiers for PKIG Gene
This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in osteogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for PKIG Gene
PKIG (CAMP-Dependent Protein Kinase Inhibitor Gamma) is a Protein Coding gene. Diseases associated with PKIG include Theileriasis. Among its related pathways are Myometrial Relaxation and Contraction Pathways and Activation of cAMP-Dependent PKA. Gene Ontology (GO) annotations related to this gene include cAMP-dependent protein kinase inhibitor activity. An important paralog of this gene is PKIA.
UniProtKB/Swiss-Prot Summary for PKIG Gene
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.