Aliases for PKIB Gene
External Ids for PKIB Gene
Previous HGNC Symbols for PKIB Gene
Previous GeneCards Identifiers for PKIB Gene
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
GeneCards Summary for PKIB Gene
PKIB (CAMP-Dependent Protein Kinase Inhibitor Beta) is a Protein Coding gene. Diseases associated with PKIB include Prostate Cancer. Among its related pathways are Signal transduction_PKA signaling and Myometrial Relaxation and Contraction Pathways. Gene Ontology (GO) annotations related to this gene include cAMP-dependent protein kinase inhibitor activity. An important paralog of this gene is PKIA.
UniProtKB/Swiss-Prot Summary for PKIB Gene
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.