This locus represents naturally-occurring readthrough transcription between two unprocessed pseudogenes, PKD1P6 (polycystic kidney disease 1 (autosomal dominant) pseudogene 6) and NPIPP1 (nuclear pore complex interacting protein pseudogene 1). The individual pseudogene loci are not curated as transcribed regions. Readthrough transcripts likely do not encode functional proteins.... See more...

Aliases for PKD1P6-NPIPP1 Gene

Aliases for PKD1P6-NPIPP1 Gene

  • PKD1P6-NPIPP1 Readthrough 3
  • Polycystin-1-Like 3
  • Novel Transcript 5
  • NONHSAG018696.2 91
  • NONHSAG018697.2 91
  • HSALNG0109787 164
  • AC139256.3 5
  • Lnc-RRN3-3 165

External Ids for PKD1P6-NPIPP1 Gene

Previous GeneCards Identifiers for PKD1P6-NPIPP1 Gene

  • GC16M015137
  • GC16M015138
  • GC16M015164

Summaries for PKD1P6-NPIPP1 Gene

Entrez Gene Summary for PKD1P6-NPIPP1 Gene

  • This locus represents naturally-occurring readthrough transcription between two unprocessed pseudogenes, PKD1P6 (polycystic kidney disease 1 (autosomal dominant) pseudogene 6) and NPIPP1 (nuclear pore complex interacting protein pseudogene 1). The individual pseudogene loci are not curated as transcribed regions. Readthrough transcripts likely do not encode functional proteins. [provided by RefSeq, Jan 2016]

GeneCards Summary for PKD1P6-NPIPP1 Gene

PKD1P6-NPIPP1 (PKD1P6-NPIPP1 Readthrough) is a Pseudogene. Diseases associated with PKD1P6-NPIPP1 include Breast Cancer and Polycystic Kidney Disease.

Additional gene information for PKD1P6-NPIPP1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PKD1P6-NPIPP1 Gene

Genomics for PKD1P6-NPIPP1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PKD1P6-NPIPP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J015133 Enhancer 0.2 Ensembl 600.7 -1.9 -1900 0.2 PKD1P6-NPIPP1 MIR6511B2 lnc-RRN3-4 piR-51780-002 PKD1P6 RRN3 PDXDC1 NPIPA5
GH16J015122 Enhancer 0.2 Ensembl 0.4 +8.6 8600 0.4 NPIPP1 NTAN1 PKD1P6-NPIPP1 piR-53957-004 RRN3 PDXDC1 NPIPA5
GH16J015117 Enhancer 0.2 Ensembl 0.4 +13.4 13400 1.2 NPIPP1 piR-53957-004 PKD1P6-NPIPP1 RRN3 PDXDC1 NPIPA5
GH16J015112 Enhancer 0.2 Ensembl 0.4 +17.9 17900 1.4 piR-53957-004 NPIPP1 RRN3 PKD1P6-NPIPP1 PDXDC1 NPIPA5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PKD1P6-NPIPP1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for PKD1P6-NPIPP1 Gene

Genomic Locations for PKD1P6-NPIPP1 Gene
chr16:15,104,723-15,131,601
(GRCh38/hg38)
Size:
26,879 bases
Orientation:
Minus strand
chr16:15,198,580-15,225,458
(GRCh37/hg19)
Size:
26,879 bases
Orientation:
Minus strand

Genomic View for PKD1P6-NPIPP1 Gene

Genes around PKD1P6-NPIPP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PKD1P6-NPIPP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PKD1P6-NPIPP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PKD1P6-NPIPP1 Gene

Proteins for PKD1P6-NPIPP1 Gene

Post-translational modifications for PKD1P6-NPIPP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PKD1P6-NPIPP1 Gene

Domains & Families for PKD1P6-NPIPP1 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PKD1P6-NPIPP1 Gene

Function for PKD1P6-NPIPP1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PKD1P6-NPIPP1 Gene

Localization for PKD1P6-NPIPP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PKD1P6-NPIPP1 Gene

Pathways & Interactions for PKD1P6-NPIPP1 Gene

PathCards logo

SuperPathways for PKD1P6-NPIPP1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for PKD1P6-NPIPP1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PKD1P6-NPIPP1 Gene

Drugs & Compounds for PKD1P6-NPIPP1 Gene

No Compound Related Data Available

Transcripts for PKD1P6-NPIPP1 Gene

mRNA/cDNA for PKD1P6-NPIPP1 Gene

10 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
4 RNACentral transcripts :
3 NONCODE transcripts :
2 LncBook transcripts :
4 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for PKD1P6-NPIPP1 Gene

No ASD Table

Relevant External Links for PKD1P6-NPIPP1 Gene

GeneLoc Exon Structure for
PKD1P6-NPIPP1

Expression for PKD1P6-NPIPP1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PKD1P6-NPIPP1

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PKD1P6-NPIPP1 Gene

Orthologs for PKD1P6-NPIPP1 Gene

Evolution for PKD1P6-NPIPP1 Gene

ENSEMBL:
Gene Tree for PKD1P6-NPIPP1 (if available)
TreeFam:
Gene Tree for PKD1P6-NPIPP1 (if available)

No data available for Orthologs for PKD1P6-NPIPP1 Gene

Paralogs for PKD1P6-NPIPP1 Gene

No data available for Paralogs for PKD1P6-NPIPP1 Gene

Variants for PKD1P6-NPIPP1 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for PKD1P6-NPIPP1 Gene

Disorders for PKD1P6-NPIPP1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for PKD1P6-NPIPP1 Gene - From: LncRNADisease and GeneCards

Disorder Aliases PubMed IDs
breast cancer
  • breast lobular carcinoma
polycystic kidney disease
  • pkd
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for PKD1P6-NPIPP1

genes like me logo Genes that share disorders with PKD1P6-NPIPP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PKD1P6-NPIPP1 Gene

Publications for PKD1P6-NPIPP1 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3
  4. Homologues to the first gene for autosomal dominant polycystic kidney disease are pseudogenes. (PMID: 11414761) Bogdanova N … Dworniczak B (Genomics 2001) 3
  5. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. (PMID: 7566098) Adams MD … White O (Nature 1995) 3

No data available for Mastermind for PKD1P6-NPIPP1 Gene

Products for PKD1P6-NPIPP1 Gene

Sources for PKD1P6-NPIPP1 Gene