Aliases for PITPNA Gene
External Ids for PITPNA Gene
Previous HGNC Symbols for PITPNA Gene
Previous GeneCards Identifiers for PITPNA Gene
This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.[provided by RefSeq, Sep 2009]
GeneCards Summary for PITPNA Gene
PITPNA (Phosphatidylinositol Transfer Protein Alpha) is a Protein Coding gene. Diseases associated with PITPNA include Hereditary Choroidal Atrophy and Partial Central Choroid Dystrophy. Among its related pathways are Netrin-1 signaling and Developmental Biology. Gene Ontology (GO) annotations related to this gene include lipid binding and phosphatidylcholine transporter activity. An important paralog of this gene is PITPNB.
UniProtKB/Swiss-Prot for PITPNA Gene
Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.