This locus represents naturally occurring read-through transcription between the neighboring pirin (GeneID 8544) and vascular endothelial growth factor D (GeneID 2277) genes on chromosome X. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Feb 2011] See more...

Aliases for PIR-FIGF Gene

Subcategory (RNA class) for PIR-FIGF Gene

lncRNA

Number of RNA Genes sources:

2 / 17

Aliases for PIR-FIGF Gene

  • PIR-FIGF Readthrough 3
  • HSALNG0136776 164
  • HSALNG0136775 164
  • Lnc-VEGFD-1 165

External Ids for PIR-FIGF Gene

Previous GeneCards Identifiers for PIR-FIGF Gene

  • GC0XU901729
  • GC0XM015366

Summaries for PIR-FIGF Gene

Entrez Gene Summary for PIR-FIGF Gene

  • This locus represents naturally occurring read-through transcription between the neighboring pirin (GeneID 8544) and vascular endothelial growth factor D (GeneID 2277) genes on chromosome X. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for PIR-FIGF Gene

PIR-FIGF (PIR-FIGF Readthrough) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for PIR-FIGF Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PIR-FIGF Gene

Genomics for PIR-FIGF Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PIR-FIGF Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ015492 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 600.7 +0.2 166 2.2 CTCF PRDM10 IKZF1 ZNF692 BACH1 JUND ZIC2 RBFOX2 PKNOX1 ZNF24 PIR PIR-FIGF VEGFD BMX
GH0XJ015471 Enhancer 0.8 Ensembl ENCODE 0.4 +21.7 21726 1.3 CTCF JUND ZNF143 REST RAD21 TRIM22 CEBPB RUNX3 ZNF316 USF1 PIR VEGFD BMX PIR-FIGF
GH0XJ015465 Enhancer 0.9 Ensembl ENCODE 0.3 +28.0 27987 1.8 BACH1 TCF12 IKZF2 TRIM22 ARID3A DPF2 RELB JUND BCL11A ARNT BMX PIR PIR-FIGF
GH0XJ015473 Enhancer 0.7 FANTOM5 Ensembl ENCODE 0.4 +18.0 17965 2.9 ARNT TBX21 YY1 PIR VEGFD BMX PIR-FIGF
GH0XJ015468 Enhancer 0.8 Ensembl ENCODE 0.3 +25.1 25083 0.5 CTCF REST RAD21 HMBOX1 CEBPB ZBTB48 SMC3 ZBTB17 GATA3 ZNF654 BMX PIR PIR-FIGF
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PIR-FIGF on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for PIR-FIGF Gene

Genomic Locations for PIR-FIGF Gene
chrX:15,345,591-15,493,288
(GRCh38/hg38)
Size:
147,698 bases
Orientation:
Minus strand
chrX:15,363,713-15,509,432
(GRCh37/hg19)
Size:
145,720 bases
Orientation:
Minus strand

Genomic View for PIR-FIGF Gene

Genes around PIR-FIGF on UCSC Golden Path with GeneCards custom track
PIR-FIGF in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
PIR-FIGF Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PIR-FIGF Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PIR-FIGF Gene

Proteins for PIR-FIGF Gene

Post-translational modifications for PIR-FIGF Gene

No Post-translational modifications

No data available for DME Specific Peptides for PIR-FIGF Gene

Domains & Families for PIR-FIGF Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PIR-FIGF Gene

Function for PIR-FIGF Gene

Phenotypes From GWAS Catalog for PIR-FIGF Gene

genes like me logo Genes that share phenotypes with PIR-FIGF: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PIR-FIGF Gene

Localization for PIR-FIGF Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PIR-FIGF Gene

Pathways & Interactions for PIR-FIGF Gene

PathCards logo

SuperPathways for PIR-FIGF Gene

No Data Available

Gene Ontology (GO) - Biological Process for PIR-FIGF Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PIR-FIGF Gene

Drugs & Compounds for PIR-FIGF Gene

No Compound Related Data Available

Transcripts for PIR-FIGF Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for PIR-FIGF Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075A9F9_9606 lncRNA 2582 2

RefSeq: NR_037859,

LNCipedia: lnc-VEGFD-1:2,

URS00008C14FE_9606 lncRNA 514 2

LncBook: HSALNT0280454,

LNCipedia: lnc-VEGFD-1:1,

URS0000D6DDFF_9606 lncRNA 417 2

LncBook: HSALNT0280453,

LNCipedia: lnc-VEGFD-1:3,

URS0000D6EA6C_9606 lncRNA 600 1

LNCipedia: lnc-VEGFD-1:4,

PIR-FIGF in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for PIR-FIGF Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for PIR-FIGF Gene

No ASD Table

Relevant External Links for PIR-FIGF Gene

GeneLoc Exon Structure for
PIR-FIGF

Expression for PIR-FIGF Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PIR-FIGF Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PIR-FIGF

genes like me logo Genes that share expression patterns with PIR-FIGF: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PIR-FIGF Gene

Orthologs for PIR-FIGF Gene

No data available for Orthologs and Evolution for PIR-FIGF Gene

Paralogs for PIR-FIGF Gene

No data available for Paralogs for PIR-FIGF Gene

Variants for PIR-FIGF Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PIR-FIGF Gene

SNP ID Clinical significance and condition Chr 0X pos Variation AA Info Type
717759 Benign: not provided 15,456,011(-) C/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
717762 Benign: not provided 15,456,039(-) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
740215 Likely Benign: not provided 15,358,015(-) G/A NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
775779 Benign: not provided 15,390,251(-) C/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
778978 Benign: not provided 15,355,260(-) T/C NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for PIR-FIGF Gene

Structural Variations from Database of Genomic Variants (DGV) for PIR-FIGF Gene

Variant ID Type Subtype PubMed ID
dgv2228e212 CNV loss 25503493
esv2669590 CNV deletion 23128226
esv2739977 CNV deletion 23290073
esv3380907 CNV insertion 20981092
esv3558643 CNV deletion 23714750
nsv515969 CNV gain 19592680
nsv518666 CNV loss 19592680
nsv521301 CNV gain 19592680
nsv528343 CNV gain 19592680
nsv6813 CNV deletion 18451855

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Additional Variant Information for PIR-FIGF Gene

Disorders for PIR-FIGF Gene

No disorders were found for PIR-FIGF Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for PIR-FIGF Gene

Publications for PIR-FIGF Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3

No data available for Mastermind for PIR-FIGF Gene

Products for PIR-FIGF Gene

Sources for PIR-FIGF Gene