Aliases for PIP5K1B Gene
External Ids for PIP5K1B Gene
Previous GeneCards Identifiers for PIP5K1B Gene
GeneCards Summary for PIP5K1B Gene
PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Beta) is a Protein Coding gene. Diseases associated with PIP5K1B include Friedreich Ataxia. Among its related pathways are Downstream signaling events of B Cell Receptor (BCR) and Signaling by Wnt. Gene Ontology (GO) annotations related to this gene include phosphatidylinositol phosphate kinase activity and 1-phosphatidylinositol-4-phosphate 5-kinase activity. An important paralog of this gene is PIP5K1C.
UniProtKB/Swiss-Prot Summary for PIP5K1B Gene
Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion (By similarity).