Aliases for PINK1-AS Gene

Subcategory (RNA class) for PINK1-AS Gene

lncRNA

Number of RNA Genes sources:

2 / 17

Aliases for PINK1-AS Gene

  • PINK1 Antisense RNA 2 3 5
  • PINK1-AS 2 5 165
  • PINK1 Antisense RNA 1 (Non-Protein Coding) 2 3
  • PINK1AS 2 3
  • PINK1 Antisense RNA (Non-Protein Coding) 2
  • HSALNG0001461 164
  • PINK1-AS1 3
  • FLJ00387 2
  • NAPINK1 3
  • NaPINK1 2

External Ids for PINK1-AS Gene

Previous HGNC Symbols for PINK1-AS Gene

  • PINK1-AS1

Previous GeneCards Identifiers for PINK1-AS Gene

  • GC01M020970

Summaries for PINK1-AS Gene

GeneCards Summary for PINK1-AS Gene

PINK1-AS (PINK1 Antisense RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with PINK1-AS include Glucose Metabolism Disease and Parkinson Disease, Late-Onset.

Additional gene information for PINK1-AS Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PINK1-AS Gene

Genomics for PINK1-AS Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PINK1-AS Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J020652 Promoter 0.3 EPDnew 600.7 0.0 -12 0.1 PINK1-AS lnc-KIF17-2 CDA FAM43B DDOST PINK1
GH01J020642 Enhancer 0.2 Ensembl 0.4 +9.3 9292 0.2 CDA piR-46431 piR-50437-015 PINK1 PINK1-AS DDOST
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PINK1-AS on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for PINK1-AS Gene

Genomic Locations for PINK1-AS Gene
chr1:20,642,656-20,652,193
(GRCh38/hg38)
Size:
9,538 bases
Orientation:
Minus strand
chr1:20,969,150-20,978,686
(GRCh37/hg19)
Size:
9,537 bases
Orientation:
Minus strand

Genomic View for PINK1-AS Gene

Genes around PINK1-AS on UCSC Golden Path with GeneCards custom track
PINK1-AS in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
PINK1-AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PINK1-AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PINK1-AS Gene

Proteins for PINK1-AS Gene

Post-translational modifications for PINK1-AS Gene

No Post-translational modifications

No data available for DME Specific Peptides for PINK1-AS Gene

Domains & Families for PINK1-AS Gene

Gene Families for PINK1-AS Gene

Suggested Antigen Peptide Sequences for PINK1-AS Gene

GenScript: Design optimal peptide antigens:
  • FLJ00387 protein (Q8NF15_HUMAN)
genes like me logo Genes that share domains with PINK1-AS: view

No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PINK1-AS Gene

Function for PINK1-AS Gene

Phenotypes From GWAS Catalog for PINK1-AS Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PINK1-AS Gene

Localization for PINK1-AS Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PINK1-AS gene
Compartment Confidence
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PINK1-AS Gene

Pathways & Interactions for PINK1-AS Gene

PathCards logo

SuperPathways for PINK1-AS Gene

No Data Available

Gene Ontology (GO) - Biological Process for PINK1-AS Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PINK1-AS Gene

Drugs & Compounds for PINK1-AS Gene

No Compound Related Data Available

Transcripts for PINK1-AS Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for PINK1-AS Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000052446E_9606 lncRNA 4443 4

HGNC: 38872,

RefSeq: NR_046507,

Ensembl: ENST00000451424 (view in UCSC) ,

LNCipedia: PINK1-AS:1,

URS0000EB1FE5_9606 lncRNA 4446 1

LncBook: HSALNT0289387,

URS00008C1272_9606 lncRNA 352 1

LNCipedia: PINK1-AS:2,

PINK1-AS in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for PINK1-AS Gene

3 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for PINK1-AS Gene

No ASD Table

Relevant External Links for PINK1-AS Gene

GeneLoc Exon Structure for
PINK1-AS

Expression for PINK1-AS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PINK1-AS Gene

mRNA expression in normal human tissues for PINK1-AS Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PINK1-AS

genes like me logo Genes that share expression patterns with PINK1-AS: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PINK1-AS Gene

Orthologs for PINK1-AS Gene

Evolution for PINK1-AS Gene

ENSEMBL:
Gene Tree for PINK1-AS (if available)
TreeFam:
Gene Tree for PINK1-AS (if available)

No data available for Orthologs for PINK1-AS Gene

Paralogs for PINK1-AS Gene

No data available for Paralogs for PINK1-AS Gene

Variants for PINK1-AS Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PINK1-AS Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
652873 Uncertain Significance: Parkinson disease 6, autosomal recessive early-onset 20,645,562(-) A/G MISSENSE_VARIANT
662914 Uncertain Significance: Parkinson disease 6, autosomal recessive early-onset 20,645,696(-) G/A MISSENSE_VARIANT
703421 Conflicting Interpretations: Parkinson disease 6, autosomal recessive early-onset; not provided 20,648,612(-) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
703805 Benign: Parkinson disease 6, autosomal recessive early-onset 20,650,447(-) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
703838 Benign: Parkinson disease 6, autosomal recessive early-onset 20,644,661(-) C/T SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for PINK1-AS Gene

Structural Variations from Database of Genomic Variants (DGV) for PINK1-AS Gene

Variant ID Type Subtype PubMed ID
nsv1003348 CNV gain 25217958
nsv1122307 CNV deletion 24896259
nsv1137740 CNV deletion 24896259
nsv545731 CNV gain 21841781
nsv834369 CNV loss 17160897

Additional Variant Information for PINK1-AS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PINK1-AS

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PINK1-AS Gene

Disorders for PINK1-AS Gene

MalaCards: The human disease database

(7) MalaCards diseases for PINK1-AS Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
glucose metabolism disease
  • disorder of glucose metabolism
parkinson disease, late-onset
  • pd
breast cancer
  • breast lobular carcinoma
parkinson disease 6, autosomal recessive early-onset
  • park6
early-onset parkinson's disease
  • early-onset parkinson disease
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for PINK1-AS

genes like me logo Genes that share disorders with PINK1-AS: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PINK1-AS Gene

Publications for PINK1-AS Gene

  1. The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function. (PMID: 17362513) Scheele C … Timmons JA (BMC genomics 2007) 2 3
  2. Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration? (PMID: 17567565) Scheele C … Timmons JA (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007) 3
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3

Products for PINK1-AS Gene

Sources for PINK1-AS Gene