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PIFO (Primary Cilia Formation) is a Protein Coding gene. Diseases associated with PIFO include Short-Rib Thoracic Dysplasia 14 With Polydactyly and Orofaciodigital Syndrome I. Gene Ontology (GO) annotations related to this gene include protein kinase binding and beta-tubulin binding.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 20643351 |
GO:0008092 | cytoskeletal protein binding | IBA | 21873635 |
GO:0017137 | Rab GTPase binding | IPI | 20643351 |
GO:0019894 | kinesin binding | IPI | 20643351 |
GO:0019901 | protein kinase binding | IPI | 20643351 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005794 | Golgi apparatus | IEA | -- |
GO:0005802 | trans-Golgi network | ISS | -- |
GO:0031410 | cytoplasmic vesicle | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0030030 | cell projection organization | IEA | -- |
GO:0031344 | regulation of cell projection organization | IBA,ISS | -- |
GO:0033674 | positive regulation of kinase activity | IMP | 20643351 |
ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||||||
SP2: | - | ||||||||||||||||||||||||
SP3: | - | - | |||||||||||||||||||||||
SP4: | - | - | - | ||||||||||||||||||||||
SP5: |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | PIFO 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | LOC611691 30 |
|
||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
Cow (Bos Taurus) |
Mammalia | C3H1orf88 30 |
|
||
PIFO 31 |
|
OneToOne | |||
Mouse (Mus musculus) |
Mammalia | Pifo 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Pifo 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | PIFO 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | PIFO 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | PIFO 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | PIFO 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | PIFO 31 |
|
OneToOne | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.3194 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs150508940 | - | p.Arg80Lys | |||
rs15396 | - | p.Lys97Asn | |||
rs2184884 | - | p.His105Asn |
Disorder | Aliases | PubMed IDs |
---|---|---|
short-rib thoracic dysplasia 14 with polydactyly |
|
|
orofaciodigital syndrome i |
|
|
joubert syndrome 23 |
|
|
bardet-biedl syndrome 4 |
|
|
joubert syndrome 1 |
|
|