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Aliases for PICSAR Gene

Subcategory (RNA class) for PICSAR Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for PICSAR Gene

  • P38 Inhibited Cutaneous Squamous Cell Carcinoma Associated LincRNA 2 3 5
  • Long Intergenic Non-Protein Coding RNA 162 2 3
  • Putative Narcolepsy Candidate Region 1 Gene C Protein 3
  • Narcolepsy Candidate Region 1 Gene C 2
  • Chromosome 21 Open Reading Frame 113 2
  • Narcolepsy Candidate Region Gene 1C 3
  • Non-Protein Coding RNA 162 2
  • NCRNA00162 3
  • C21orf113 3
  • LINC00162 3
  • NLC1-C 3
  • PRED74 3
  • NLC1C 3

External Ids for PICSAR Gene

Previous HGNC Symbols for PICSAR Gene

  • C21orf113
  • NCRNA00162
  • LINC00162

Previous GeneCards Identifiers for PICSAR Gene

  • GC21M045844
  • GC21M045000
  • GC21M045099
  • GC21M045212
  • GC21M045244
  • GC21M045386
  • GC21M045509
  • GC21M045658
  • GC21M045755

Summaries for PICSAR Gene

GeneCards Summary for PICSAR Gene

PICSAR (P38 Inhibited Cutaneous Squamous Cell Carcinoma Associated LincRNA) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with PICSAR include Narcolepsy and Embryonal Testis Carcinoma.

Additional gene information for PICSAR Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PICSAR Gene

Genomics for PICSAR Gene

GeneHancer (GH) Regulatory Elements for PICSAR Gene

Promoters and enhancers for PICSAR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J045003 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 600.7 +0.4 378 1.9 ATF1 PKNOX1 HDAC1 CHD2 NKRF JUN GABPA MGA TGIF2 MBD1 PICSAR SUMO3 LINC00165 ITGB2-AS1 ENSG00000184441 ITGB2
GH21J044916 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 6.6 +79.6 79613 17.8 SP1 ZNF148 NKRF POLR2A ZNF687 NCOA3 MCM2 MYC SP7 RELA FAM207A ITGB2 POFUT2 UBE2G2 ENSG00000273027 TRPM2 PTTG1IP ITGB2-AS1 LINC01547 PWP2
GH21J045128 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 4.8 -125.3 -125314 3.8 CTCF MAFK MYC SP7 PRDM1 RAD21 SMARCA4 RXRA ZBTB33 ZNF600 SSR4P1 ADARB1 LINC00315 ITGB2 PICSAR LOC105372835 GC21M046952
GH21J044217 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 5 +783.5 783546 6.4 SP1 ZNF121 ZNF687 MAFK RELA MLLT1 SMARCA4 ZBED1 IKZF1 POLR2A ICOSLG GATD3A PWP2 ENSG00000232124 TRPM2-AS PICSAR TRPM2 TRAPPC10 PIR49071 LOC105372832
GH21J045011 Enhancer 1 ENCODE 0.4 -8.0 -8027 3.9 CTCF ELF3 CEBPG RERE ZSCAN21 AHR TFE3 SP7 HNF1A PPARG ADARB1 SSR4P1 PICSAR
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PICSAR on UCSC Golden Path with GeneCards custom track

Genomic Locations for PICSAR Gene

Genomic Locations for PICSAR Gene
chr21:44,999,208-45,004,727
(GRCh38/hg38)
Size:
5,520 bases
Orientation:
Minus strand
chr21:46,419,122-46,424,642
(GRCh37/hg19)
Size:
5,521 bases
Orientation:
Minus strand

Genomic View for PICSAR Gene

Genes around PICSAR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PICSAR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PICSAR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PICSAR Gene

Proteins for PICSAR Gene

Post-translational modifications for PICSAR Gene

No Post-translational modifications

No data available for DME Specific Peptides for PICSAR Gene

Domains & Families for PICSAR Gene

Gene Families for PICSAR Gene

Suggested Antigen Peptide Sequences for PICSAR Gene

GenScript: Design optimal peptide antigens:
  • Putative narcolepsy candidate region 1 gene C protein (CU113_HUMAN)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PICSAR: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for PICSAR Gene

Function for PICSAR Gene

Phenotypes From GWAS Catalog for PICSAR Gene

Animal Model Products

CRISPR Products

miRNA for PICSAR Gene

miRTarBase miRNAs that target PICSAR

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PICSAR Gene

Localization for PICSAR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PICSAR Gene

Pathways & Interactions for PICSAR Gene

PathCards logo

SuperPathways for PICSAR Gene

No Data Available

Interacting Proteins for PICSAR Gene

Gene Ontology (GO) - Biological Process for PICSAR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PICSAR Gene

Drugs & Compounds for PICSAR Gene

No Compound Related Data Available

Transcripts for PICSAR Gene

mRNA/cDNA for PICSAR Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNA Central transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for PICSAR Gene

No ASD Table

Relevant External Links for PICSAR Gene

GeneLoc Exon Structure for
PICSAR
ECgene alternative splicing isoforms for
PICSAR

Expression for PICSAR Gene

NURSA nuclear receptor signaling pathways regulating expression of PICSAR Gene:

PICSAR
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PICSAR Gene

Orthologs for PICSAR Gene

Evolution for PICSAR Gene

ENSEMBL:
Gene Tree for PICSAR (if available)
TreeFam:
Gene Tree for PICSAR (if available)

No data available for Orthologs for PICSAR Gene

Paralogs for PICSAR Gene

No data available for Paralogs for PICSAR Gene

Variants for PICSAR Gene

Sequence variations from dbSNP and Humsavar for PICSAR Gene

SNP ID Clin Chr 21 pos Variation AA Info Type
rs1000151530 -- 45,002,806(-) C/T intron_variant
rs1000709877 -- 44,998,851(-) G/A/T downstream_transcript_variant
rs1000808357 -- 45,002,943(-) G/A intron_variant
rs1001997150 -- 45,003,201(-) C/T intron_variant
rs1002150548 -- 44,999,283(-) C/T non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for PICSAR Gene

Variant ID Type Subtype PubMed ID
nsv526277 CNV loss 19592680
nsv587818 CNV loss 21841781
nsv834110 CNV loss 17160897
nsv953650 CNV deletion 24416366

Additional Variant Information for PICSAR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PICSAR

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PICSAR Gene

Disorders for PICSAR Gene

MalaCards: The human disease database

(3) MalaCards diseases for PICSAR Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
narcolepsy
  • narcolepsy, without cataplexy
embryonal testis carcinoma
  • embryonal carcinoma of testis
squamous cell carcinoma
  • epidermoid carcinoma
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for PICSAR

genes like me logo Genes that share disorders with PICSAR: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PICSAR Gene

Publications for PICSAR Gene

  1. Long Noncoding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity. (PMID: 27049681) Piipponen M … Kähäri VM (The Journal of investigative dermatology 2016) 2 3 58
  2. Genomewide association analysis of human narcolepsy and a new resistance gene. (PMID: 16826516) Kawashima M … Tokunaga K (American journal of human genetics 2006) 2 3 58
  3. Long non-coding RNA PICSAR decreases adhesion and promotes migration of squamous carcinoma cells by downregulating α2β1 and α5β1 integrin expression. (PMID: 30429154) Piipponen M … Nissinen L (Biology open 2018) 3 58
  4. Downregulation of miR-320a/383-sponge-like long non-coding RNA NLC1-C (narcolepsy candidate-region 1 genes) is associated with male infertility and promotes testicular embryonal carcinoma cell proliferation. (PMID: 26539909) Lü M … Sun F (Cell death & disease 2015) 3 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 58

Products for PICSAR Gene

Sources for PICSAR Gene

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