Aliases for PICSAR Gene

Data sources for PICSAR Gene:

RNA type for PICSAR Gene

lncRNA

Aliases for PICSAR Gene

External Ids for PICSAR Gene

Previous HGNC Symbols for PICSAR Gene

  • C21orf113
  • NCRNA00162
  • LINC00162

Previous GeneCards Identifiers for PICSAR Gene

  • GC21M045844
  • GC21M046593
  • GC21M046622
  • GC21M047155
  • GC21M045000
  • GC21M045099
  • GC21M045212
  • GC21M045244
  • GC21M045386
  • GC21M045509
  • GC21M045658
  • GC21M045755
  • GC21M047420
  • GC21M047693

Summaries for PICSAR Gene

GeneCards Summary for PICSAR Gene

PICSAR (P38 Inhibited Cutaneous Squamous Cell Carcinoma Associated LincRNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with PICSAR include Embryonal Testis Carcinoma and Narcolepsy.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PICSAR Gene

Genomics for PICSAR Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PICSAR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J045003 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE 250.7 +0.5 473 2.1 BHLHE40 MNT MAX NKRF STAT3 USF2 GABPA MBD1 SMARCA4 RAD51 PICSAR lnc-FAM207A-3 SUMO3 LINC00165 ITGB2-AS1 ENSG00000184441 ITGB2 FAM207A ADARB1
GH21J044916 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 6.6 +79.6 79614 17.8 BCLAF1 SP1 ZNF207 IKZF1 POLR2A ZIC2 MXD4 NONO CTCF REST ITGB2-AS1 FAM207A ITGB2 POFUT2 UBE2G2 ENSG00000273027 TRPM2 PTTG1IP LINC01547 PWP2
GH21J045128 Promoter/Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 4.8 -125.3 -125313 3.8 BCLAF1 ZNF654 ZNF600 JUND ATF2 ZNF10 ZIC2 CEBPB CTCF REST HSALNG0133607 ADARB1 SSR4P1 LINC00315 ITGB2 PICSAR NONHSAG033067.2 POFUT2
GH21J044223 Enhancer 0.8 Ensembl ENCODE 5 +781.8 781827 2.6 POLR2A ZIC2 TARDBP MAFF ZNF316 MAFK BHLHE40 MYC MAX FOXA1 piR-43105-409 GATD3A PWP2 ICOSLG TRPM2-AS PICSAR lnc-DNMT3L-1
GH21J044954 Enhancer 0.6 Ensembl dbSUPER 6.1 +49.0 49027 1 ZIC2 BHLHE40 EGR2 PRDM10 ZFHX2 ENSG00000273027 SSR4P1 ADARB1 LINC01424 UBE2G2 PTTG1IP SUMO3 TSPEAR-AS2 LINC00334 FAM207A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PICSAR on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for PICSAR Gene

Latest Assembly
chr21:44,999,207-45,004,728
(GRCh38/hg38)
Size:
5,522 bases
Orientation:
Minus strand

Previous Assembly
chr21:46,419,122-46,424,642
(GRCh37/hg19 by Entrez Gene)
Size:
5,521 bases
Orientation:
Minus strand

Genomic View for PICSAR Gene

Genes around PICSAR on UCSC Golden Path with GeneCards custom track
PICSAR in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
PICSAR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PICSAR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PICSAR Gene

Proteins for PICSAR Gene

Post-translational modifications for PICSAR Gene

No Post-translational modifications

No data available for DME Specific Peptides for PICSAR Gene

Domains & Families for PICSAR Gene

Gene Families for PICSAR Gene

Suggested Antigen Peptide Sequences for PICSAR Gene

GenScript: Design optimal peptide antigens:
  • Putative narcolepsy candidate region 1 gene C protein (CU113_HUMAN)
genes like me logo Genes that share domains with PICSAR: view

No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PICSAR Gene

Function for PICSAR Gene

Phenotypes From GWAS Catalog for PICSAR Gene

CRISPR products for research

miRNA for PICSAR Gene

miRTarBase miRNAs that target PICSAR

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PICSAR Gene

Localization for PICSAR Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PICSAR gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PICSAR Gene

Pathways & Interactions for PICSAR Gene

PathCards logo

SuperPathways for PICSAR Gene

No Data Available

Gene Ontology (GO) - Biological Process for PICSAR Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PICSAR Gene

Drugs & Compounds for PICSAR Gene

No Compound Related Data Available

Transcripts for PICSAR Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for PICSAR Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000076787D_9606 lncRNA 735 3

Ensembl: ENST00000615826 (view in UCSC) ,

LNCipedia: PICSAR:3,

NONCODE: NONHSAT082908.2,

URS000075EA8F_9606 lncRNA 733 1

RefSeq: NR_024089,

URS00008B67C1_9606 lncRNA 239 3

LncBook: HSALNT0274575,

LNCipedia: PICSAR:4,

NONCODE: NONHSAT082909.2,

URS00009AE974_9606 lncRNA 804 1

NONCODE: NONHSAT191592.1,

URS0001BD6437_9606 lncRNA 804 1

LncBook: HSALNT0274573,

PICSAR in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for PICSAR Gene

2 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for PICSAR Gene

No ASD Table

Relevant External Links for PICSAR Gene

GeneLoc Exon Structure for
PICSAR

Expression for PICSAR Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PICSAR

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PICSAR Gene

Orthologs for PICSAR Gene

Evolution for PICSAR Gene

ENSEMBL:
Gene Tree for PICSAR (if available)
TreeFam:
Gene Tree for PICSAR (if available)
Alliance of Genome Resources:
Additional Orthologs for PICSAR

No data available for Orthologs for PICSAR Gene

Paralogs for PICSAR Gene

No data available for Paralogs for PICSAR Gene

Variants for PICSAR Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for PICSAR Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for PICSAR Gene

Variant ID Type Subtype PubMed ID
nsv526277 CNV loss 19592680
nsv587818 CNV loss 21841781
nsv834110 CNV loss 17160897
nsv953650 CNV deletion 24416366

Additional Variant Information for PICSAR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PICSAR
Leiden Open Variation Database (LOVD)
PICSAR

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for PICSAR Gene

Disorders for PICSAR Gene

MalaCards: The human disease database

(3) MalaCards diseases for PICSAR Gene - From: LNC, COP, and GCD

Disorder Aliases PubMed IDs
embryonal testis carcinoma
  • embryonal carcinoma of testis
narcolepsy
  • narcolepsy, without cataplexy
squamous cell carcinoma
  • epidermoid carcinoma
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for PICSAR

genes like me logo Genes that share disorders with PICSAR: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PICSAR Gene

Publications for PICSAR Gene

  1. Long Noncoding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity. (PMID: 27049681) Piipponen M … Kähäri VM (The Journal of investigative dermatology 2016) 2 3 72
  2. Genomewide association analysis of human narcolepsy and a new resistance gene. (PMID: 16826516) Kawashima M … Tokunaga K (American journal of human genetics 2006) 2 3 72
  3. Downregulation of miR-320a/383-sponge-like long non-coding RNA NLC1-C (narcolepsy candidate-region 1 genes) is associated with male infertility and promotes testicular embryonal carcinoma cell proliferation. (PMID: 26539909) Lü M … Sun F (Cell death & disease 2015) 3 72
  4. LINC00162 confers sensitivity to 5-Aza-2'-deoxycytidine via modulation of an RNA splicing protein, HNRNPH1. (PMID: 30914798) Zong L … Ushijima T (Oncogene 2019) 3
  5. LncRNA PICSAR promotes cell proliferation, migration and invasion of fibroblast-like synoviocytes by sponging miRNA-4701-5p in rheumatoid arthritis. (PMID: 31791845) Bi X … Zheng SG (EBioMedicine 2019) 3

Products for PICSAR Gene

Sources for PICSAR Gene