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Aliases for PI4KAP2 Gene

Aliases for PI4KAP2 Gene

  • Phosphatidylinositol 4-Kinase Alpha Pseudogene 2 2 3 5
  • Phosphatidylinositol 4-Kinase, Catalytic, Alpha Pseudogene 2 2 3
  • Phosphatidylinositol 4-Kinase, Catalytic, Alpha Polypeptide Pseudogene 2 3
  • Putative Phosphatidylinositol 4-Kinase Alpha-Like Protein P2 3

External Ids for PI4KAP2 Gene

Previous GeneCards Identifiers for PI4KAP2 Gene

  • GC22M020158
  • GC22M021828
  • GC22M004865

Summaries for PI4KAP2 Gene

GeneCards Summary for PI4KAP2 Gene

PI4KAP2 (Phosphatidylinositol 4-Kinase Alpha Pseudogene 2) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include kinase activity and phosphotransferase activity, alcohol group as acceptor.

Gene Wiki entry for PI4KAP2 Gene

Additional gene information for PI4KAP2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PI4KAP2 Gene

Genomics for PI4KAP2 Gene

GeneHancer (GH) Regulatory Elements for PI4KAP2 Gene

Promoters and enhancers for PI4KAP2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J021516 Promoter 0.5 Ensembl 650.7 +0.2 232 1.8 PI4KAP2 GC22P022066
GH22J020916 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 32 +598.6 598636 5.7 HNRNPUL1 PKNOX1 CLOCK MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 CRKL LZTR1 MED15 TRMT2A SNAP29 SERPIND1 PI4KAP2 DGCR8 ZNF74 PPIL2
GH22J020855 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 22.2 +659.6 659575 4.1 PKNOX1 FOXA2 CLOCK MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SNAP29 PI4KA LZTR1 SERPIND1 PI4KAP2 THAP7-AS1 MED15 DGCR8 ZDHHC8 TRMT2A
GH22J021665 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 22.3 -148.7 -148710 2.1 HDGF PKNOX1 CLOCK SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 PPIL2 THAP7-AS1 LZTR1 IGLV5-52 PI4KAP2 TOP3B ENSG00000273342 THAP7 ENSG00000272779 ENSG00000224086
GH22J020978 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 12.3 +536.0 535969 5.3 HDGF PKNOX1 SMAD1 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 LZTR1 ENSG00000272829 THAP7-AS1 LOC100420177 TRMT2A THAP7 PI4KAP2 ABHD17AP4 ENSG00000273342 ENSG00000273343
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PI4KAP2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the PI4KAP2 gene promoter:
  • Lmo2
  • Arnt
  • AhR
  • HNF-4alpha2
  • HNF-4alpha1
  • c-Jun
  • c-Fos
  • AP-1
  • CHOP-10
  • C/EBPalpha

Genomic Locations for PI4KAP2 Gene

Genomic Locations for PI4KAP2 Gene
44,536 bases
Minus strand
44,536 bases
Minus strand

Genomic View for PI4KAP2 Gene

Genes around PI4KAP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PI4KAP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PI4KAP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PI4KAP2 Gene

Proteins for PI4KAP2 Gene

  • Protein details for PI4KAP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative phosphatidylinositol 4-kinase alpha-like protein P2
    Protein Accession:
    Secondary Accessions:
    • Q6ICJ0
    • Q6ZT68
    • Q8WUK7

    Protein attributes for PI4KAP2 Gene

    592 amino acids
    Molecular mass:
    66944 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI39842.2; Type=Miscellaneous discrepancy; Note=Contaminating sequence.; Evidence={ECO:0000305};

    Alternative splice isoforms for PI4KAP2 Gene


neXtProt entry for PI4KAP2 Gene

Post-translational modifications for PI4KAP2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for PI4KAP2 Gene

Domains & Families for PI4KAP2 Gene

Protein Domains for PI4KAP2 Gene

Suggested Antigen Peptide Sequences for PI4KAP2 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
  • Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
genes like me logo Genes that share domains with PI4KAP2: view

No data available for Gene Families for PI4KAP2 Gene

Function for PI4KAP2 Gene

Phenotypes From GWAS Catalog for PI4KAP2 Gene

Gene Ontology (GO) - Molecular Function for PI4KAP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004430 1-phosphatidylinositol 4-kinase activity IBA --
GO:0052742 phosphatidylinositol kinase activity IBA --
genes like me logo Genes that share ontologies with PI4KAP2: view
genes like me logo Genes that share phenotypes with PI4KAP2: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PI4KAP2 Gene

Localization for PI4KAP2 Gene

Gene Ontology (GO) - Cellular Components for PI4KAP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA --
GO:0005886 plasma membrane IBA --
GO:0016020 membrane IBA --
genes like me logo Genes that share ontologies with PI4KAP2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for PI4KAP2 Gene

Pathways & Interactions for PI4KAP2 Gene

SuperPathways for PI4KAP2 Gene

No Data Available

Interacting Proteins for PI4KAP2 Gene

Selected Interacting proteins: A4QPH2-PI4P2_HUMAN for PI4KAP2 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for PI4KAP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030036 actin cytoskeleton organization IBA --
GO:0046854 phosphatidylinositol phosphorylation IEA --
GO:0048015 phosphatidylinositol-mediated signaling IBA --
genes like me logo Genes that share ontologies with PI4KAP2: view

No data available for Pathways by source and SIGNOR curated interactions for PI4KAP2 Gene

Drugs & Compounds for PI4KAP2 Gene

No Compound Related Data Available

Transcripts for PI4KAP2 Gene

mRNA/cDNA for PI4KAP2 Gene

(8) Additional mRNA sequences :
(207) Selected AceView cDNA sequences:
(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PI4KAP2 Gene

Phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for PI4KAP2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9
SP1: -

Relevant External Links for PI4KAP2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PI4KAP2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PI4KAP2 Gene

Protein differential expression in normal tissues from HIPED for PI4KAP2 Gene

This gene is overexpressed in Heart (43.4) and Brain (25.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PI4KAP2 Gene

Protein tissue co-expression partners for PI4KAP2 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PI4KAP2 Gene:


SOURCE GeneReport for Unigene cluster for PI4KAP2 Gene:

genes like me logo Genes that share expression patterns with PI4KAP2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PI4KAP2 Gene

Orthologs for PI4KAP2 Gene

Evolution for PI4KAP2 Gene

Gene Tree for PI4KAP2 (if available)
Gene Tree for PI4KAP2 (if available)

No data available for Orthologs for PI4KAP2 Gene

Paralogs for PI4KAP2 Gene

(4) SIMAP similar genes for PI4KAP2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with PI4KAP2: view

No data available for Paralogs for PI4KAP2 Gene

Variants for PI4KAP2 Gene

Sequence variations from dbSNP and Humsavar for PI4KAP2 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000053309 -- 21,508,611(-) T/C intron_variant
rs1000271661 -- 21,511,222(-) T/C intron_variant
rs1000323872 -- 21,476,937(-) T/C intron_variant
rs1000436034 -- 21,485,886(-) G/A intron_variant
rs1000548320 -- 21,487,094(-) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for PI4KAP2 Gene

Variant ID Type Subtype PubMed ID
dgv4486n100 CNV gain 25217958
dgv4487n100 CNV gain 25217958
dgv4488n100 CNV gain 25217958
dgv4489n100 CNV gain 25217958
dgv4490n100 CNV gain 25217958
dgv4491n100 CNV gain 25217958
dgv820e199 CNV deletion 23128226
esv25508 CNV gain+loss 19812545
esv2678291 CNV deletion 23128226
esv2760719 CNV gain 21179565
esv2763699 CNV gain+loss 21179565
esv3584494 CNV gain 24956385
esv3893444 CNV gain 25118596
nsv1066391 CNV gain 25217958
nsv1072202 CNV deletion 25765185
nsv1073155 CNV deletion 25765185
nsv1118947 CNV deletion 24896259
nsv1126624 CNV deletion 24896259
nsv1126625 CNV deletion 24896259
nsv1133538 CNV deletion 24896259
nsv1144967 CNV deletion 24896259
nsv1160729 CNV duplication 26073780
nsv1160730 CNV deletion 26073780
nsv192 OTHER inversion 15895083
nsv428386 CNV loss 18775914
nsv436864 CNV insertion 17901297
nsv442791 CNV gain 18776908
nsv469545 CNV gain 16826518
nsv471596 CNV gain+loss 15918152
nsv511071 OTHER inversion 20534489
nsv7350 OTHER inversion 18451855
nsv834145 CNV loss 17160897
nsv953042 CNV deletion 24416366
nsv966081 CNV duplication 23825009

Additional Variant Information for PI4KAP2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PI4KAP2 Gene

Disorders for PI4KAP2 Gene

Additional Disease Information for PI4KAP2

No disorders were found for PI4KAP2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PI4KAP2 Gene

Publications for PI4KAP2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins JE … Dunham I (Genome biology 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for PI4KAP2 Gene

Sources for PI4KAP2 Gene

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