Aliases for PI4KAP1 Gene

Aliases for PI4KAP1 Gene

  • Phosphatidylinositol 4-Kinase Alpha Pseudogene 1 2 3 5
  • Phosphatidylinositol 4-Kinase, Catalytic, Alpha Pseudogene 1 2 3
  • Phosphatidylinositol 4-Kinase, Catalytic, Alpha Polypeptide Pseudogene 1 3
  • Putative Inactive Phosphatidylinositol 4-Kinase Alpha-Like Protein P1 4
  • PI4KAP1 5

External Ids for PI4KAP1 Gene

Previous GeneCards Identifiers for PI4KAP1 Gene

  • GC22M018764
  • GC22M020383
  • GC22P004815

Summaries for PI4KAP1 Gene

GeneCards Summary for PI4KAP1 Gene

PI4KAP1 (Phosphatidylinositol 4-Kinase Alpha Pseudogene 1) is a Pseudogene.

Additional gene information for PI4KAP1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PI4KAP1 Gene

Genomics for PI4KAP1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PI4KAP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J018572 Promoter 0.8 Ensembl 0.7 +2.2 2167 6.4 ARHGAP35 MTA2 YBX3 NKRF POLR2A EGR1 HDGF GATAD2A TRIM25 DPF2 UFD1 PI4KAP1 lnc-GGTLC3-4 piR-57460-432 RIMBP3 TMEM191B
GH22J018571 Promoter 0.3 Ensembl 0.4 +7.5 7467 0.2 piR-57460-432 PI4KAP1 lnc-GGTLC3-4 lnc-TMEM191B-5 RIMBP3 TMEM191B
GH22J018570 Promoter 0.3 Ensembl 0.4 +6.7 6667 0.2 PI4KAP1 piR-57460-432 lnc-GGTLC3-4 RIMBP3 TMEM191B
GH22J018573 Promoter 0.3 Ensembl 0.4 +7.1 7067 0.2 PI4KAP1 piR-57460-432 lnc-GGTLC3-4 RIMBP3 TMEM191B
GH22J018557 Promoter 0.3 Ensembl 0.4 +19.8 19767 0.4 piR-57460-432 lnc-TMEM191B-5 lnc-GGTLC3-4 PI4KAP1 TMEM191B RIMBP3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PI4KAP1 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the PI4KAP1 gene promoter:
  • AML1a
  • E47
  • Hand1
  • Hlf
  • HTF
  • MZF-1
  • NF-1
  • NF-1/L
  • RORalpha1
  • RP58

Genomic Locations for PI4KAP1 Gene

Genomic Locations for PI4KAP1 Gene
chr22:18,533,646-18,577,968
(GRCh38/hg38)
Size:
44,323 bases
Orientation:
Minus strand
chr22:20,383,524-20,427,835
(GRCh37/hg19)
Size:
44,312 bases
Orientation:
Minus strand

Genomic View for PI4KAP1 Gene

Genes around PI4KAP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PI4KAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PI4KAP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PI4KAP1 Gene

Proteins for PI4KAP1 Gene

  • Protein details for PI4KAP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8J0-PI4P1_HUMAN
    Recommended name:
    Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1
    Protein Accession:
    Q8N8J0

    Protein attributes for PI4KAP1 Gene

    Size:
    262 amino acids
    Molecular mass:
    29179 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PI4KAP1 Gene

Post-translational modifications for PI4KAP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PI4KAP1 Gene

Domains & Families for PI4KAP1 Gene

Protein Domains for PI4KAP1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PI4KAP1 Gene

GenScript: Design optimal peptide antigens:
  • Putative phosphatidylinositol 4-kinase alpha-like protein P1 (PI4P1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8N8J0

UniProtKB/Swiss-Prot:

PI4P1_HUMAN :
  • Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
Family:
  • Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
genes like me logo Genes that share domains with PI4KAP1: view

No data available for Gene Families for PI4KAP1 Gene

Function for PI4KAP1 Gene

Gene Ontology (GO) - Molecular Function for PI4KAP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004430 1-phosphatidylinositol 4-kinase activity IBA 21873635
GO:0052742 phosphatidylinositol kinase activity IBA 21873635
genes like me logo Genes that share ontologies with PI4KAP1: view
genes like me logo Genes that share phenotypes with PI4KAP1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PI4KAP1 Gene

Localization for PI4KAP1 Gene

Gene Ontology (GO) - Cellular Components for PI4KAP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA 21873635
GO:0005886 plasma membrane IBA 21873635
GO:0016020 membrane IBA 21873635
genes like me logo Genes that share ontologies with PI4KAP1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for PI4KAP1 Gene

Pathways & Interactions for PI4KAP1 Gene

PathCards logo

SuperPathways for PI4KAP1 Gene

No Data Available

Interacting Proteins for PI4KAP1 Gene

Selected Interacting proteins: Q8N8J0-PI4P1_HUMAN for PI4KAP1 Gene via IID

Symbol External ID(s) Details
PI4KA

Gene Ontology (GO) - Biological Process for PI4KAP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046854 phosphatidylinositol phosphorylation IBA 21873635
GO:0048015 phosphatidylinositol-mediated signaling IBA 21873635
genes like me logo Genes that share ontologies with PI4KAP1: view

No data available for Pathways by source and SIGNOR curated interactions for PI4KAP1 Gene

Drugs & Compounds for PI4KAP1 Gene

No Compound Related Data Available

Transcripts for PI4KAP1 Gene

mRNA/cDNA for PI4KAP1 Gene

6 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for PI4KAP1 Gene

No ASD Table

Relevant External Links for PI4KAP1 Gene

GeneLoc Exon Structure for
PI4KAP1

Expression for PI4KAP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PI4KAP1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PI4KAP1

SOURCE GeneReport for Unigene cluster for PI4KAP1 Gene:

Hs.592456
genes like me logo Genes that share expression patterns with PI4KAP1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PI4KAP1 Gene

Orthologs for PI4KAP1 Gene

Evolution for PI4KAP1 Gene

ENSEMBL:
Gene Tree for PI4KAP1 (if available)
TreeFam:
Gene Tree for PI4KAP1 (if available)

No data available for Orthologs for PI4KAP1 Gene

Paralogs for PI4KAP1 Gene

(3) SIMAP similar genes for PI4KAP1 Gene using alignment to 1 proteins:

  • PI4P1_HUMAN
genes like me logo Genes that share paralogs with PI4KAP1: view

No data available for Paralogs for PI4KAP1 Gene

Variants for PI4KAP1 Gene

Structural Variations from Database of Genomic Variants (DGV) for PI4KAP1 Gene

Variant ID Type Subtype PubMed ID
dgv1283e212 CNV gain 25503493
dgv16n31 CNV gain 19718026
dgv173e55 CNV gain 17911159
dgv2431n106 OTHER inversion 24896259
dgv4466n100 CNV gain+loss 25217958
dgv4467n100 CNV gain 25217958
dgv7963n54 CNV gain 21841781
dgv7964n54 CNV loss 21841781
dgv7965n54 CNV gain 21841781
dgv7987n54 CNV gain 21841781
dgv7988n54 CNV gain 21841781
dgv7989n54 CNV gain 21841781
dgv7990n54 CNV gain 21841781
dgv99e203 CNV gain+loss 21179565
esv2144483 CNV deletion 18987734
esv22247 CNV gain+loss 19812545
esv26930 CNV gain+loss 19812545
esv2751935 CNV loss 17911159
esv2758824 CNV gain+loss 17122850
esv32687 CNV gain+loss 17666407
esv3381183 CNV duplication 20981092
esv3575418 CNV gain 25503493
nsv1055756 CNV gain 25217958
nsv1061694 CNV gain 25217958
nsv1071779 CNV deletion 25765185
nsv1144015 CNV deletion 24896259
nsv1146969 CNV duplication 26484159
nsv428385 CNV gain+loss 18775914
nsv469578 CNV gain 16826518
nsv471339 CNV gain 19718026
nsv471594 CNV gain+loss 15918152
nsv511636 CNV loss 21212237
nsv516997 CNV gain+loss 19592680
nsv588139 CNV loss 21841781
nsv588264 CNV loss 21841781
nsv588281 CNV loss 21841781
nsv820540 CNV duplication 20802225
nsv953028 CNV deletion 24416366
nsv962755 CNV duplication 23825009
nsv964587 CNV duplication 23825009

Additional Variant Information for PI4KAP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PI4KAP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for PI4KAP1 Gene

Disorders for PI4KAP1 Gene

No disorders were found for PI4KAP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PI4KAP1 Gene

Publications for PI4KAP1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for PI4KAP1 Gene

Sources for PI4KAP1 Gene