Aliases for PHPT1 Gene
External Ids for PHPT1 Gene
Previous GeneCards Identifiers for PHPT1 Gene
This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
GeneCards Summary for PHPT1 Gene
PHPT1 (Phosphohistidine Phosphatase 1) is a Protein Coding gene. Diseases associated with PHPT1 include Retinohepatoendocrinologic Syndrome. Gene Ontology (GO) annotations related to this gene include ion channel binding and calcium channel inhibitor activity.
UniProtKB/Swiss-Prot Summary for PHPT1 Gene
Exhibits phosphohistidine phosphatase activity.