Aliases for PHLDA1 Gene
External Ids for PHLDA1 Gene
Previous GeneCards Identifiers for PHLDA1 Gene
This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008]
GeneCards Summary for PHLDA1 Gene
PHLDA1 (Pleckstrin Homology Like Domain Family A Member 1) is a Protein Coding gene. Diseases associated with PHLDA1 include Morpheaform Basal Cell Carcinoma and Fibroepithelial Basal Cell Carcinoma. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. An important paralog of this gene is PHLDA3.
UniProtKB/Swiss-Prot Summary for PHLDA1 Gene
Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.