Aliases for PHGR1 Gene

Aliases for PHGR1 Gene

  • Proline, Histidine And Glycine Rich 1 2 3 5
  • Proline, Histidine And Glycine-Rich Protein 1 3 4
  • Proline/Histidine/Glycine-Rich 1 2 3
  • Proline-Histidine-Glycin-Rich Protein 1 3
  • PHGR1 5

External Ids for PHGR1 Gene

Previous GeneCards Identifiers for PHGR1 Gene

  • GC15P038425
  • GC15P040644
  • GC15P017486

Summaries for PHGR1 Gene

GeneCards Summary for PHGR1 Gene

PHGR1 (Proline, Histidine And Glycine Rich 1) is a Protein Coding gene. Diseases associated with PHGR1 include Diverticulitis Of Colon and Diverticulitis.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PHGR1 Gene

Genomics for PHGR1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PHGR1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PHGR1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PHGR1

Genomic Locations for PHGR1 Gene

Latest Assembly
chr15:40,351,033-40,356,434
(GRCh38/hg38)
Size:
5,402 bases
Orientation:
Plus strand

Previous Assembly
chr15:40,643,234-40,648,635
(GRCh37/hg19 by Entrez Gene)
Size:
5,402 bases
Orientation:
Plus strand

chr15:40,643,234-40,648,635
(GRCh37/hg19 by Ensembl)
Size:
5,402 bases
Orientation:
Plus strand

Genomic View for PHGR1 Gene

Genes around PHGR1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PHGR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PHGR1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PHGR1 Gene

Proteins for PHGR1 Gene

  • Protein details for PHGR1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9JFL3-PHGR1_HUMAN
    Recommended name:
    Proline, histidine and glycine-rich protein 1
    Protein Accession:
    C9JFL3

    Protein attributes for PHGR1 Gene

    Size:
    82 amino acids
    Molecular mass:
    7706 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PHGR1 Gene

Post-translational modifications for PHGR1 Gene

No Post-translational modifications

Other Protein References for PHGR1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PHGR1 Gene

Domains & Families for PHGR1 Gene

Gene Families for PHGR1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for PHGR1 Gene

GenScript: Design optimal peptide antigens:
  • Proline, histidine and glycine-rich protein 1 (PHGR1_HUMAN)
genes like me logo Genes that share domains with PHGR1: view

No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PHGR1 Gene

Function for PHGR1 Gene

Phenotypes From GWAS Catalog for PHGR1 Gene

Phenotypes for PHGR1 Gene

genes like me logo Genes that share phenotypes with PHGR1: view

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PHGR1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PHGR1 Gene

Localization for PHGR1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PHGR1 gene
Compartment Confidence
extracellular 3
plasma membrane 1
peroxisome 1
endoplasmic reticulum 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PHGR1 Gene

Pathways & Interactions for PHGR1 Gene

PathCards logo

SuperPathways for PHGR1 Gene

No Data Available

Interacting Proteins for PHGR1 Gene

Gene Ontology (GO) - Biological Process for PHGR1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PHGR1 Gene

Drugs & Compounds for PHGR1 Gene

No Compound Related Data Available

Transcripts for PHGR1 Gene

mRNA/cDNA for PHGR1 Gene

1 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PHGR1

Alternative Splicing Database (ASD) splice patterns (SP) for PHGR1 Gene

No ASD Table

Relevant External Links for PHGR1 Gene

GeneLoc Exon Structure for
PHGR1

Expression for PHGR1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PHGR1 Gene

mRNA differential expression in normal tissues according to GTEx for PHGR1 Gene

This gene is overexpressed in Colon - Transverse (x31.0) and Small Intestine - Terminal Ileum (x19.5).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PHGR1

SOURCE GeneReport for Unigene cluster for PHGR1 Gene:

Hs.447537

Evidence on tissue expression from TISSUES for PHGR1 Gene

  • Stomach(2.4)
  • Intestine(2.2)
genes like me logo Genes that share expression patterns with PHGR1: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PHGR1 Gene

Orthologs for PHGR1 Gene

Evolution for PHGR1 Gene

ENSEMBL:
Gene Tree for PHGR1 (if available)
TreeFam:
Gene Tree for PHGR1 (if available)
Alliance of Genome Resources:
Additional Orthologs for PHGR1

No data available for Orthologs for PHGR1 Gene

Paralogs for PHGR1 Gene

No data available for Paralogs for PHGR1 Gene

Variants for PHGR1 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for PHGR1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for PHGR1 Gene

Variant ID Type Subtype PubMed ID
esv34145 CNV loss 18971310
nsv1160287 CNV duplication 26073780
nsv510660 CNV deletion 20534489

Variation tolerance for PHGR1 Gene

Gene Damage Index Score: 1.83; 34.38% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PHGR1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PHGR1
Leiden Open Variation Database (LOVD)
PHGR1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PHGR1 Gene

Disorders for PHGR1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for PHGR1 Gene - From: COP

Disorder Aliases PubMed IDs
diverticulitis of colon
  • colonic diverticular disease
diverticulitis
- elite association - COSMIC cancer census association via MalaCards
Search PHGR1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for PHGR1

genes like me logo Genes that share disorders with PHGR1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PHGR1 Gene

Publications for PHGR1 Gene

  1. Expression profiling and intracellular localization studies of the novel Proline-, Histidine-, and Glycine-rich protein 1 suggest an essential role in gastro-intestinal epithelium and a potential clinical application in colorectal cancer diagnostics. (PMID: 29415677) Oltedal S … Nordgård O (BMC gastroenterology 2018) 2 3
  2. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 4
  3. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh JH … Kim NS (Mammalian genome : official journal of the International Mammalian Genome Society 2005) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for PHGR1 Gene

Sources for PHGR1 Gene