Aliases for PHF7 Gene
External Ids for PHF7 Gene
Previous GeneCards Identifiers for PHF7 Gene
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. This gene is expressed in the testis in Sertoli cells but not germ cells. The protein encoded by this gene contains plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. The protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
GeneCards Summary for PHF7 Gene
PHF7 (PHD Finger Protein 7) is a Protein Coding gene. Diseases associated with PHF7 include Granulomatous Orchitis and Polyposis Syndrome, Hereditary Mixed, 1. An important paralog of this gene is G2E3.
UniProtKB/Swiss-Prot Summary for PHF7 Gene
May play a role in spermatogenesis.