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Aliases for PGS1 Gene
Aliases for PGS1 Gene
External Ids for PGS1 Gene
- HGNC: 30029
- Entrez Gene: 9489
- Ensembl: ENSG00000087157
- OMIM: 614942
- UniProtKB: Q32NB8
Previous GeneCards Identifiers for PGS1 Gene
- GC17P076214
- GC17P079761
- GC17P076835
- GC17P076971
- GC17P073886
- GC17P076374
- GC17P071797
Summaries for PGS1 Gene
GeneCards Summary for PGS1 Gene
PGS1 (Phosphatidylglycerophosphate Synthase 1) is a Protein Coding gene. Diseases associated with PGS1 include Cone-Rod Dystrophy 1. Among its related pathways are Metabolism and Glycerophospholipid biosynthesis. Gene Ontology (GO) annotations related to this gene include calcium ion binding and CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity.
UniProtKB/Swiss-Prot Summary for PGS1 Gene
-
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
Additional gene information for PGS1 Gene
- HGNC(30029)
- Entrez Gene(9489)
- Ensembl(ENSG00000087157)
- OMIM(614942)
- UniProtKB(Q32NB8)
- Open Targets Platform(ENSG00000087157)
- Search for PGS1 at DataMed
- Search for PGS1 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PGS1 Gene
Genomics for PGS1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for PGS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around PGS1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PGS1
- Top Transcription factor binding sites by QIAGEN in the PGS1 gene promoter:
-
- AP-4
- c-Myb
- IRF-7A
- NRSF form 1
- NRSF form 2
- STAT5B
Genomic Locations for PGS1 Gene
Genomic Locations for PGS1 Gene
- chr17:78,378,623-78,425,114
- (GRCh38/hg38)
- Size:
- 46,492 bases
- Orientation:
- Plus strand
- chr17:76,374,721-76,421,195
- (GRCh37/hg19)
- Size:
- 46,475 bases
- Orientation:
- Plus strand
Genomic View for PGS1 Gene
Genes around PGS1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.3 by HGNC
- 17q25.3 by Entrez Gene
- 17q25.3 by Ensembl
PGS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PGS1 Gene
Proteins for PGS1 Gene
-
Protein details for PGS1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q32NB8-PGPS1_HUMAN
- Recommended name:
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
- Protein Accession:
- Q32NB8
- B7ZA32
- Q8IYK9
- Q8TA85
- Q96A75
- Q9H7G9
- Q9NPW7
Protein attributes for PGS1 Gene
- Size:
- 556 amino acids
- Molecular mass:
- 62730 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH08903.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH15570.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH35662.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; Sequence=AAH35662.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=BAB14921.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
Protein Expression for PGS1 Gene
Selected DME Specific Peptides for PGS1 Gene
- Q32NB8:
-
- PGLAALLGRLSDRL
- LLIPERFNETIGLQHIKVYLFD
- VTETLLTEAER
- VTSPPCCLC
- PDTWIYPLIQMKPF
- LEKSLQAKFPS
- TLIGSPNFG
- ILLASPEVNGFFGAKGVAGAIP
- EIADFFTELVDA
- TRGSRGRKNSRTML
- WLLLAPLL
- HRFQWIRNLVPEFG
Post-translational modifications for PGS1 Gene
Other Protein References for PGS1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for PGS1
-
Abcam antibodies for PGS1
- Invitrogen Antibodies for PGS1 (AFLGC-PGS1)
- Sino Biological Antibodies for PGS1
Protein Products
-
OriGene Purified Proteins for PGS1
- Search Origene for MassSpec and Protein Over-expression Lysates for PGS1
- Origene Custom Protein Services for PGS1
- antibodies-online: Show 3 available PGS1 Proteins ranked by validation data
- Compare Top PGS1 Proteins
-
Quality Products:
-
Signalway Proteins for PGS1
-
Abcam proteins for PGS1
Assay Products
- antibodies-online: Show 16 available PGS1 Elisa Kits ranked by validation data
- Compare Top PGS1 Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for PGS1
Domains & Families for PGS1 Gene
Gene Families for PGS1 Gene
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for PGS1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for PGS1 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ55337, highly similar to Homo sapiens phosphatidylglycerophosphate synthase 1 (PGS1), mRNA (B4DLU3_HUMAN)
- Phosphatidylglycerophosphate synthase 1 (PGPS1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q32NB8UniProtKB/Swiss-Prot:
PGPS1_HUMAN :- Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
- Family:
-
- Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
Function for PGS1 Gene
Molecular function for PGS1 Gene
- UniProtKB/Swiss-Prot Function:
- Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+); Xref=Rhea:RHEA:12593, ChEBI:CHEBI:15378, ChEBI:CHEBI:57597, ChEBI:CHEBI:58332, ChEBI:CHEBI:60110, ChEBI:CHEBI:60377; EC=2.7.8.5;.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Activated by calcium and magnesium and inhibited by other bivalent cations.
Enzyme Numbers (IUBMB) for PGS1 Gene
Phenotypes From GWAS Catalog for PGS1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003824 | catalytic activity | IEA | -- |
| GO:0005509 | calcium ion binding | ISS | -- |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0008444 | CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity | IEA,ISS | -- |
Phenotypes for PGS1 Gene
- MGI mutant phenotypes for PGS1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for PGS1:
Animal Models for PGS1 Gene
- MGI Knock Outs for PGS1:
-
- Pgs1 Pgs1<tm1b(EUCOMM)Hmgu>
Animal Model Products
-
Taconic Biosciences Mouse Models for PGS1
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PGS1 - Select products 50% OFF >
- * PGS1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PGS1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PGS1
-
Santa Cruz Biotechnology (SCBT) CRISPR for PGS1
miRNA for PGS1 Gene
- miRTarBase miRNAs that target PGS1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PGS1
- Browse OriGene Inhibitory RNA Products For PGS1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PGS1
Clone Products
- Applied Biological Materials (abm): Clones for PGS1 - Select products 50% OFF >
- * PGS1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PGS1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PGS1
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PGS1 Gene
Localization for PGS1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PGS1 Gene
- Mitochondrion.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| endoplasmic reticulum | 4 |
| plasma membrane | 2 |
| cytoskeleton | 2 |
| extracellular | 1 |
| nucleus | 1 |
| cytosol | 1 |
| peroxisome | 0 |
| lysosome | 0 |
- Cell Junctions (2)
- Intermediate filaments (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA,ISS | -- |
| GO:0005743 | mitochondrial inner membrane | TAS | 11171073 |
| GO:0005783 | endoplasmic reticulum | IDA | -- |
Pathways & Interactions for PGS1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Glycerophospholipid biosynthesis |
.01
|
|
| 2 | Metabolism |
.40
|
|
| 3 | cardiolipin biosynthesis | ||
| 4 | Glycerophospholipid Biosynthetic Pathway | ||
Pathways by source for PGS1 Gene
2 BioSystems pathways for PGS1 Gene
5 Reactome pathways for PGS1 Gene
2 KEGG pathways for PGS1 Gene
UniProtKB/Swiss-Prot Q32NB8-PGPS1_HUMAN
- Pathway: Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.
Interacting Proteins for PGS1 Gene
GPS-Prot Interaction Network for PGS1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0006655 | phosphatidylglycerol biosynthetic process | IEA,ISS | -- |
| GO:0008654 | phospholipid biosynthetic process | IEA | -- |
| GO:0032049 | cardiolipin biosynthetic process | IEA,ISS | -- |
| GO:0046339 | diacylglycerol metabolic process | ISS | -- |
No data available for SIGNOR curated interactions for PGS1 Gene
Drugs & Compounds for PGS1 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| CDP-DG(16:0/16:0) |
|
|
||||
| CDP-DG(16:0/18:0) |
|
|
||||
| CDP-DG(16:0/18:1(11Z)) |
|
|
||||
| CDP-DG(16:0/18:1(9Z)) |
|
|
||||
| CDP-DG(16:0/18:2(9Z,12Z)) |
|
|
Transcripts for PGS1 Gene
mRNA/cDNA for PGS1 Gene
- 1 REFSEQ mRNAs :
- 19 NCBI additional mRNA sequence :
- 15 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000262764 2297 nts (view in UCSC)
- ENST00000585521 721 nts (view in UCSC)
- ENST00000586019 572 nts (view in UCSC)
- ENST00000586325 537 nts (view in UCSC)
- ENST00000586355 584 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PGS1 - Select products 50% OFF >
- * PGS1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PGS1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PGS1
-
Santa Cruz Biotechnology (SCBT) CRISPR for PGS1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PGS1
- Browse OriGene Inhibitory RNA Products For PGS1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PGS1
Clone Products
- Applied Biological Materials (abm): Clones for PGS1 - Select products 50% OFF >
- * PGS1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PGS1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PGS1
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | · | 9c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||
| SP6: |
Relevant External Links for PGS1 Gene
- GeneLoc Exon Structure for
- PGS1
Expression for PGS1 Gene
mRNA differential expression in normal tissues according to GTEx for PGS1 Gene
This gene is overexpressed in Whole Blood (x9.3).
This gene is overexpressed in Plasma (62.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PGS1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PGS1
SOURCE GeneReport for Unigene cluster for PGS1 Gene:
Hs.654671Evidence on tissue expression from TISSUES for PGS1 Gene
- Nervous system(4.6)
- Pancreas(4.2)
- Blood(4.1)
- Liver(2.1)
Primer Products
-
OriGene qPCR primer pairs for PGS1
-
OriGene qPCR primer pairs and template standards for PGS1
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PGS1 Gene
Orthologs for PGS1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | PGS1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | PGS1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | PGS1 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Pgs1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Pgs1 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | PGS1 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | PGS1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | PGS1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | PGS1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | pgs1 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | PGS1 (1 of 2) 31 |
|
OneToMany | |
| LOC100534896 30 |
|
||||
| PGS1 (2 of 2) 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG7718 30 31 32 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002662 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | pgs-1 30 31 |
|
OneToOne | |
| Y48G1C.4 32 |
|
|
|||
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AAL003W 30 |
|
||
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0A08580g 30 |
|
||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PGS1 30 31 33 |
|
OneToOne | |
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU01141 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPBP18G5.02 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for PGS1 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for PGS1 Gene
- ENSEMBL:
- Gene Tree for PGS1 (if available)
- TreeFam:
- Gene Tree for PGS1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PGS1: view image
Paralogs for PGS1 Gene
(15) SIMAP similar genes for PGS1 Gene using alignment to 9 proteins:
- PGPS1_HUMAN
- B4DLU3_HUMAN
- K7EJP6_HUMAN
- K7EL44_HUMAN
- K7ELT9_HUMAN
- K7EPX0_HUMAN
- K7EQ89_HUMAN
- K7EQF5_HUMAN
- U3KQD9_HUMAN
No data available for Paralogs for PGS1 Gene
Variants for PGS1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PGS1 Gene
| SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs372229822 | Uncertain Significance: Severe Myopia | 78,414,989(+) | G/A | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1002451 | CNV | deletion | 20482838 |
| esv3582920 | CNV | loss | 25503493 |
| nsv820049 | CNV | gain | 19587683 |
| nsv833555 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
21.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.42;
42.76% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PGS1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PGS1 Gene
Disorders for PGS1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cone-rod dystrophy 1 |
|
|
Search PGS1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for PGS1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for PGS1 Gene
Publications for PGS1 Gene
- Biological, clinical and population relevance of 95 loci for blood lipids. (PMID: 20686565) Teslovich TM … Kathiresan S (Nature 2010) 3 41
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 41
- Isolation of a chinese hamster ovary (CHO) cDNA encoding phosphatidylglycerophosphate (PGP) synthase, expression of which corrects the mitochondrial abnormalities of a PGP synthase-defective mutant of CHO-K1 cells. (PMID: 9880566) Kawasaki K … Dowhan W (The Journal of biological chemistry 1999) 2 3
- FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane. (PMID: 31056421) Ceccarelli DF … Sicheri F (Structure (London, England : 1993) 2019) 3
- Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. (PMID: 28986522) Antoniali G … Tell G (Nature communications 2017) 3
ExternalLinks
Products for PGS1 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PGS1
- Search Origene for MassSpec and Protein Over-expression Lysates for PGS1
- Origene Custom Protein Services for PGS1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PGS1
- Browse OriGene Inhibitory RNA Products For PGS1
- OriGene qPCR primer pairs for PGS1
- OriGene qPCR primer pairs and template standards for PGS1
- OriGene CRISPR knockouts for PGS1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For PGS1
- Sino Biological Human cDNA Clone for PGS1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for PGS1
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for PGS1
- Novus Biologicals proteins and lysates for PGS1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for PGS1
- Abcam proteins for PGS1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for PGS1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for PGS1 (AFLGC-PGS1)
- VectorBuilder Custom and pre-made DNA vectors for PGS1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for PGS1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for PGS1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for PGS1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for PGS1
- antibodies-online: Show 51 available PGS1 Antibodies ranked by validation data
- Compare Top PGS1 Antibodies
- antibodies-online: Show 16 available PGS1 Elisa Kits ranked by validation data
- Compare Top PGS1 Elisa Kits
- Quality Products:
- antibodies-online: Show 3 available PGS1 Proteins ranked by validation data
- Compare Top PGS1 Proteins
- Quality Products:
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PGS1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PGS1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for PGS1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PGS1
Sources for PGS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB