Aliases for PGP Gene
External Ids for PGP Gene
Previous GeneCards Identifiers for PGP Gene
GeneCards Summary for PGP Gene
PGP (Phosphoglycolate Phosphatase) is a Protein Coding gene. Diseases associated with PGP include Sennetsu Fever. Among its related pathways are Glyoxylate and dicarboxylate metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include magnesium ion binding and protein tyrosine phosphatase activity. An important paralog of this gene is PDXP.
UniProtKB/Swiss-Prot Summary for PGP Gene
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).