Aliases for PGLYRP1 Gene
External Ids for PGLYRP1 Gene
Previous HGNC Symbols for PGLYRP1 Gene
Previous GeneCards Identifiers for PGLYRP1 Gene
GeneCards Summary for PGLYRP1 Gene
PGLYRP1 (Peptidoglycan Recognition Protein 1) is a Protein Coding gene. Diseases associated with PGLYRP1 include Immunodeficiency 60 and Spherocytosis, Type 2. Among its related pathways are Defensins and Innate Immune System. Gene Ontology (GO) annotations related to this gene include peptidoglycan binding and N-acetylmuramoyl-L-alanine amidase activity. An important paralog of this gene is PGLYRP3.
UniProtKB/Swiss-Prot Summary for PGLYRP1 Gene
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.