Aliases for PGA5 Gene
Aliases for PGA5 Gene
External Ids for PGA5 Gene
- HGNC: 8887
- Entrez Gene: 5222
- Ensembl: ENSG00000256713
- OMIM: 169730
- UniProtKB: P0DJD9
Previous GeneCards Identifiers for PGA5 Gene
- GC11U990102
- GC11P062521
- GC11P060786
- GC11P060788
- GC11P060767
- GC11P060991
- GC11P061008
Summaries for PGA5 Gene
-
This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015]
GeneCards Summary for PGA5 Gene
PGA5 (Pepsinogen 5, Group I (Pepsinogen A)) is a Protein Coding gene. Diseases associated with PGA5 include Atrophic Gastritis and Gastritis. Among its related pathways are Collagen chain trimerization and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include aspartic-type endopeptidase activity. An important paralog of this gene is PGA4.
UniProtKB/Swiss-Prot for PGA5 Gene
-
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
Additional gene information for PGA5 Gene
- Monarch Initiative
- Search for PGA5 at DataMed
- Search for PGA5 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PGA5 Gene
Genomics for PGA5 Gene
GeneHancer (GH) Regulatory Elements for PGA5 Gene
Promoters and enhancers for PGA5 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH11J061240 | Promoter | 0.6 | EPDnew | 650.7 | 0.0 | -32 | 0.1 | ZNF512 | PGA5 ENSG00000256220 | |
| GH11J061223 | Promoter | 0.5 | EPDnew | 650.4 | -18.1 | -18128 | 0.1 | PGA4 PGA5 ENSG00000256220 | ||
| GH11J061293 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 0.2 | +53.7 | 53696 | 2.6 | ARID4B SIN3A FEZF1 DMAP1 ZNF48 YY1 SLC30A9 GLIS2 NFKBIZ SP5 | VWCE PGA5 | |
| GH11J061254 | Enhancer | 0.7 | ENCODE | 0.4 | +13.6 | 13562 | 0.2 | HDGF CTCF PKNOX1 RB1 ARID4B EBF1 RAD21 CTBP1 ARID2 POLR2A | VWCE DDB1 TKFC PGA5 | |
| GH11J061282 | Enhancer | 0.9 | Ensembl ENCODE | 0.3 | +40.8 | 40833 | 0.9 | KLF1 SREBF2 MAX KLF14 CCNT2 POLR2A EGR1 VEZF1 KLF8 SP3 | TKFC DDB1 TMEM216 VWCE PGA5 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around PGA5 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the PGA5 gene promoter:
-
- CP2
- FOXD1
Regulatory Element Products
Genomic Locations for PGA5 Gene
Genomic Locations for PGA5 Gene
- chr11:61,241,042-61,251,457
- (GRCh38/hg38)
- Size:
- 10,416 bases
- Orientation:
- Plus strand
- chr11:61,008,514-61,018,929
- (GRCh37/hg19)
- Size:
- 10,416 bases
- Orientation:
- Plus strand
Genomic View for PGA5 Gene
Genes around PGA5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q12.2 by Entrez Gene
- 11q12.2 by HGNC
- 11q12.2 by Ensembl
PGA5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PGA5 Gene
Proteins for PGA5 Gene
-
Protein details for PGA5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P0DJD9-PEPA5_HUMAN
- Recommended name:
- Pepsin A-5
- Protein Accession:
- P0DJD9
- A8K749
- B7ZW62
- B7ZW75
- P00790
- Q7M4R0
- Q8N1E3
Protein attributes for PGA5 Gene
- Size:
- 388 amino acids
- Molecular mass:
- 41993 Da
- Quaternary structure:
- No Data Available
Protein Expression for PGA5 Gene
Post-translational modifications for PGA5 Gene
Other Protein References for PGA5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for PGA5 (Pepsinogen A5/PGA5)
-
Custom Antibody ServicesOriGene Antibodies for PGA5
- Novus Biologicals Antibodies for PGA5
- Invitrogen Antibodies for PGA5
- GeneTex PGA5 Antibody for PGA5
-
Santa Cruz Biotechnology (SCBT) Antibodies for PGA5
Protein Products
- R&D Systems Proteins and Enzymes for PGA5 (Pepsinogen A5/PGA5)
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- Novus Biologicals lysates for PGA5
- antibodies-online: Search results for 4 available PGA5 Proteins ranked by validation data
- Compare Top PGA5 Proteins
-
Quality Products:
- Search GeneTex for Proteins for PGA5
Assay Products
- antibodies-online: Search results for available PGA5 related products ranked by validation data
No data available for DME Specific Peptides for PGA5 Gene
Domains & Families for PGA5 Gene
Gene Families for PGA5 Gene
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for PGA5 Gene
Suggested Antigen Peptide Sequences for PGA5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P0DJD9- Family:
-
- Belongs to the peptidase A1 family.
Function for PGA5 Gene
Molecular function for PGA5 Gene
- UniProtKB/Swiss-Prot Function:
- Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1 positions. Cleaves 1-Phe- -Val-2, 4-Gln- -His-5, 13-Glu- -Ala-14, 14-Ala- -Leu-15, 15-Leu- -Tyr-16, 16-Tyr- -Leu-17, 23-Gly- -Phe-24, 24-Phe- -Phe-25 and 25-Phe- -Tyr-26 bonds in the B chain of insulin.
- GENATLAS Biochemistry:
- pepsinogen 5,group I (pepsinogen A),clustered with PGA3,PGA4
Enzyme Numbers (IUBMB) for PGA5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004190 | aspartic-type endopeptidase activity | IBA | -- |
| GO:0008233 | peptidase activity | IEA,TAS | -- |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for PGA5 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PGA5
-
CRISPR Products
-
OriGene CRISPR knockouts for PGA5
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- Applied Biological Materials CRISPR for PGA5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PGA5
- GenScript: Design CRISPR guide RNA sequences for PGA5
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PGA5
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Clone Products
- Sino Biological Human cDNA Clone for PGA5
- VectorBuilder custom plasmid, inducible vectors for PGA5
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PGA5
- genomics-online: cdna clones - Search results for available PGA5 gene related products
- orf clones - Search results for available PGA5 gene related products
- Applied Biological Materials Clones for PGA5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for PGA5
No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PGA5 Gene
Localization for PGA5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PGA5 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| endosome | 4 |
| plasma membrane | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0070062 | extracellular exosome | HDA | 23533145 |
| GO:0097486 | multivesicular body lumen | TAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for PGA5 Gene
Pathways & Interactions for PGA5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Collagen chain trimerization | ||
| 2 | Metabolism of proteins | ||
| 3 | Surfactant metabolism | ||
Pathways by source for PGA5 Gene
2 Reactome pathways for PGA5 Gene
1 KEGG pathway for PGA5 Gene
Interacting Proteins for PGA5 Gene
GPS-Prot Interaction Network for PGA5
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006508 | proteolysis | IEA,IBA | -- |
| GO:0006914 | autophagy | IBA | -- |
| GO:0007586 | digestion | IEA | -- |
| GO:0030163 | protein catabolic process | IBA | -- |
| GO:0044267 | cellular protein metabolic process | TAS | -- |
No data available for SIGNOR curated interactions for PGA5 Gene
Transcripts for PGA5 Gene
mRNA/cDNA for PGA5 Gene
- (1) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (18) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000312403 1519 bps (uc001nqz.4)
- ENST00000545109 592 bps (uc058byh.1)
- ENST00000536269 576 bps (uc058byi.1)
- ENST00000535568 572 bps (uc058byj.1)
- ENST00000451616 971 bps (uc058byk.1)
Unigene Clusters for PGA5 Gene
CRISPR Products
-
OriGene CRISPR knockouts for PGA5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PGA5
- genomics-online: gRNA clones - Search results for available PGA5 gene related products
- Applied Biological Materials CRISPR for PGA5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PGA5
- GenScript: Design CRISPR guide RNA sequences for PGA5
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PGA5
- Browse OriGene Inhibitory RNA Products For PGA5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PGA5
- genomics-online: shRNA clones - Search results for available PGA5 gene related products
Clone Products
- Sino Biological Human cDNA Clone for PGA5
- VectorBuilder custom plasmid, inducible vectors for PGA5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PGA5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PGA5
- genomics-online: cdna clones - Search results for available PGA5 gene related products
- orf clones - Search results for available PGA5 gene related products
- Applied Biological Materials Clones for PGA5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for PGA5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- NULL (Uncategorized)
-
Ovary (Reproductive System)
- Mature Granulosa Cells Antral Follicle
-
Stomach (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for PGA5 Gene
This gene is overexpressed in Stomach (x52.9).
This gene is overexpressed in Urine (68.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PGA5 Gene
NURSA nuclear receptor signaling pathways regulating expression of PGA5 Gene:
PGA5SOURCE GeneReport for Unigene cluster for PGA5 Gene:
Hs.432854Evidence on tissue expression from TISSUES for PGA5 Gene
- Stomach(4.4)
- Nervous system(4.3)
- Intestine(4.1)
- Kidney(4)
Primer Products
-
OriGene qPCR primer pairs and template standards for PGA5
-
OriGene qPCR primer pairs for PGA5
- genomics-online: primer clones - Search results for available PGA5 gene related products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PGA5 Gene
Orthologs for PGA5 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PGA4 33 |
|
||
| -- 34 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | PGA 34 33 |
|
OneToMany | |
| cow (Bos Taurus) |
Mammalia | PGA5 33 |
|
||
| PGA 34 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | LOC395926 33 |
|
||
| PGA 34 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | pga4 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | pga-A 33 |
|
- Species where no ortholog for PGA5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for PGA5 Gene
- ENSEMBL:
- Gene Tree for PGA5 (if available)
- TreeFam:
- Gene Tree for PGA5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PGA5: view image
Paralogs for PGA5 Gene
Paralogs for PGA5 Gene
(8) SIMAP similar genes for PGA5 Gene using alignment to 4 proteins:
- PEPA5_HUMAN
- B7ZW66_HUMAN
- C9JM59_HUMAN
- F5GWT0_HUMAN
Variants for PGA5 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000278023 | -- | 61,247,559(+) | G/A | intron_variant | |
| rs1000705657 | -- | 61,250,582(+) | G/A | intron_variant | |
| rs1000944254 | -- | 61,250,792(+) | G/C/T | intron_variant | |
| rs1001177376 | -- | 61,251,004(+) | A/C | intron_variant | |
| rs1001195355 | -- | 61,249,475(+) | A/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2744587 | CNV | deletion | 23290073 |
| esv2759831 | CNV | gain+loss | 17122850 |
| esv29298 | CNV | gain+loss | 19812545 |
| esv3350259 | CNV | duplication | 20981092 |
| esv3353952 | CNV | duplication | 20981092 |
| esv3425930 | CNV | duplication | 20981092 |
| esv3579734 | CNV | loss | 25503493 |
| esv3626575 | CNV | loss | 21293372 |
| esv3626576 | CNV | gain | 21293372 |
| nsv1118213 | CNV | deletion | 24896259 |
| nsv339 | CNV | deletion | 18451855 |
| nsv341 | CNV | insertion | 18451855 |
| nsv428259 | CNV | gain+loss | 18775914 |
| nsv514629 | CNV | gain | 21397061 |
| nsv555162 | CNV | loss | 21841781 |
| nsv820586 | CNV | deletion | 20802225 |
| nsv825937 | CNV | loss | 20364138 |
| nsv832177 | CNV | loss | 17160897 |
| nsv8833 | CNV | gain | 18304495 |
| nsv952458 | CNV | duplication | 24416366 |
| nsv975192 | CNV | duplication | 23825009 |
Gene Damage Index Score:
2.18;
39.53% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PGA5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PGA5
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PGA5 Gene
Disorders for PGA5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| atrophic gastritis |
|
|
| gastritis |
|
|
| amyotrophic lateral sclerosis 1 |
|
|
Search PGA5 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for PGA5
No data available for UniProtKB/Swiss-Prot and Genatlas for PGA5 Gene
Publications for PGA5 Gene
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Crystal structure of human pepsin and its complex with pepstatin. (PMID: 7663352) Fujinaga M … James MN (Protein science : a publication of the Protein Society 1995) 3 4 58
- A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins. (PMID: 2515193) Athauda SB … Takahashi K (Journal of biochemistry 1989) 3 4 58
- Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family. (PMID: 2714789) Evers MP … Eriksson AW (Genomics 1989) 3 4 58
- Activation of human pepsinogens. (PMID: 3197840) Foltmann B (FEBS letters 1988) 3 4 58
Products for PGA5 Gene
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- Novus Biologicals
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- VectorBuilder custom plasmid, inducible vectors for PGA5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PGA5
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 34 available PGA5 Antibodies ranked by validation data
- Compare Top PGA5 Antibodies
- antibodies-online: Search results for available PGA5 related products ranked by validation data
- antibodies-online: Search results for 4 available PGA5 Proteins ranked by validation data
- Compare Top PGA5 Proteins
- Quality Products:
- GeneTex PGA5 Antibody for PGA5
- Search GeneTex for Proteins for PGA5
- Santa Cruz Biotechnology (SCBT) Antibodies for PGA5
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- Santa Cruz Biotechnology (SCBT) CRISPR for PGA5
- Horizon Cell Lines for PGA5
- genomics-online: cdna clones - Search results for available PGA5 gene related products
- orf clones - Search results for available PGA5 gene related products
- genomics-online: gRNA clones - Search results for available PGA5 gene related products
- genomics-online: primer clones - Search results for available PGA5 gene related products
- genomics-online: shRNA clones - Search results for available PGA5 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PGA5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PGA5
- GeneCopoeia miRNA 3'UTR Target clone products for PGA5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PGA5
Sources for PGA5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
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