Aliases for PEX11B Gene
External Ids for PEX11B Gene
Previous GeneCards Identifiers for PEX11B Gene
The protein encoded by this gene facilitates peroxisomal proliferation and interacts with PEX19. The encoded protein is found in the peroxisomal membrane. Several transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]
GeneCards Summary for PEX11B Gene
PEX11B (Peroxisomal Biogenesis Factor 11 Beta) is a Protein Coding gene. Diseases associated with PEX11B include Peroxisome Biogenesis Disorder 14B and Peroxisome Biogenesis Disorder 1B. Among its related pathways are Peroxisome. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity. An important paralog of this gene is PEX11A.
UniProtKB/Swiss-Prot for PEX11B Gene
Involved in peroxisomal proliferation (PubMed:9792670). May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane (PubMed:12618434). Promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455).