Aliases for PEX11A Gene
External Ids for PEX11A Gene
Previous GeneCards Identifiers for PEX11A Gene
This gene is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside stimuli to increase peroxisome abundance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
GeneCards Summary for PEX11A Gene
PEX11A (Peroxisomal Biogenesis Factor 11 Alpha) is a Protein Coding gene. Among its related pathways are Metabolism and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). Gene Ontology (GO) annotations related to this gene include protein homodimerization activity. An important paralog of this gene is PEX11B.
UniProtKB/Swiss-Prot for PEX11A Gene
May be involved in peroxisomal proliferation and may regulate peroxisomes division (PubMed:9792670). May mediate binding of coatomer proteins to the peroxisomal membrane (By similarity). Promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455).