Aliases for PERP Gene
External Ids for PERP Gene
Previous GeneCards Identifiers for PERP Gene
GeneCards Summary for PERP Gene
PERP (P53 Apoptosis Effector Related To PMP22) is a Protein Coding gene. Diseases associated with PERP include Erythrokeratodermia Variabilis Et Progressiva 7 and Olmsted Syndrome 2. Among its related pathways are Gene Expression and Direct p53 effectors. An important paralog of this gene is TMEM47.
UniProtKB/Swiss-Prot Summary for PERP Gene
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).