Aliases for PEDS1 Gene
External Ids for PEDS1 Gene
Previous HGNC Symbols for PEDS1 Gene
Co-transcription of this gene and the neighboring downstream gene (ubiquitin-conjugating enzyme E2 variant 1) generates a rare read-through transcript, which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. The protein encoded by this individual gene lacks a UEV1 domain but includes three transmembrane regions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
GeneCards Summary for PEDS1 Gene
PEDS1 (Plasmanylethanolamine Desaturase 1) is a Protein Coding gene. Diseases associated with PEDS1 include Chlorhexidine Allergy and Rocuronium Allergy. An important paralog of this gene is PEDS1-UBE2V1.
UniProtKB/Swiss-Prot Summary for PEDS1 Gene
Plasmanylethanolamine desaturase involved in plasmalogen biogenesis in the endoplasmic reticulum membrane (PubMed:31604315). Plasmalogens are glycerophospholipids with a hydrocarbon chain linked by a vinyl ether bond at the glycerol sn-1 position, and are involved in antioxidative and signaling mechanisms (PubMed:31604315).