Aliases for PEDS1 Gene
External Ids for PEDS1 Gene
Previous HGNC Symbols for PEDS1 Gene
Co-transcription of this gene and the neighboring downstream gene (ubiquitin-conjugating enzyme E2 variant 1) generates a rare read-through transcript, which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. The protein encoded by this individual gene lacks a UEV1 domain but includes three transmembrane regions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
GeneCards Summary for PEDS1 Gene
PEDS1 (Plasmanylethanolamine Desaturase 1) is a Protein Coding gene. Diseases associated with PEDS1 include Rocuronium Allergy and Legume Allergy. Among its related pathways are Metabolism and Acyl chain remodelling of PE. An important paralog of this gene is PEDS1-UBE2V1.
UniProtKB/Swiss-Prot Summary for PEDS1 Gene
Plasmanylethanolamine desaturase involved in plasmalogen biogenesis in the endoplasmic reticulum membrane (PubMed:31604315, PubMed:32209662). Plasmalogens are glycerophospholipids with a hydrocarbon chain linked by a vinyl ether bond at the glycerol sn-1 position, and are involved in antioxidative and signaling mechanisms (PubMed:31604315).