Aliases for PDZD8 Gene
External Ids for PDZD8 Gene
Previous HGNC Symbols for PDZD8 Gene
Previous GeneCards Identifiers for PDZD8 Gene
GeneCards Summary for PDZD8 Gene
PDZD8 (PDZ Domain Containing 8) is a Protein Coding gene.
UniProtKB/Swiss-Prot Summary for PDZD8 Gene
Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes (PubMed:29097544). PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca(2+) transfer (PubMed:29097544). In neurons, involved in the regulation of dendritic Ca(2+) dynamics by regulating mitochondrial Ca(2+) uptake in neurons (PubMed:29097544). Plays an indirect role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987). May inhibit herpes simplex virus 1 infection at an early stage (PubMed:21549406).