Aliases for PDLIM7 Gene
Aliases for PDLIM7 Gene
External Ids for PDLIM7 Gene
- HGNC: 22958
- Entrez Gene: 9260
- Ensembl: ENSG00000196923
- OMIM: 605903
- UniProtKB: Q9NR12
Previous GeneCards Identifiers for PDLIM7 Gene
- GC00U914366
- GC05M177024
- GC05M176843
- GC05M176912
- GC05M171830
Summaries for PDLIM7 Gene
-
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
GeneCards Summary for PDLIM7 Gene
PDLIM7 (PDZ And LIM Domain 7) is a Protein Coding gene. Diseases associated with PDLIM7 include Pleural Empyema and Dental Pulp Calcification. Among its related pathways are Developmental Biology and GDNF-Family Ligands and Receptor Interactions. An important paralog of this gene is LDB3.
UniProtKB/Swiss-Prot for PDLIM7 Gene
-
May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity).
Additional gene information for PDLIM7 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PDLIM7 Gene
Genomics for PDLIM7 Gene
GeneHancer (GH) Regulatory Elements for PDLIM7 Gene
Promoters and enhancers for PDLIM7 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around PDLIM7 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for PDLIM7 Gene
Genomic Locations for PDLIM7 Gene
- chr5:177,483,394-177,497,619
- (GRCh38/hg38)
- Size:
- 14,226 bases
- Orientation:
- Minus strand
- chr5:176,910,395-176,924,607
- (GRCh37/hg19)
Genomic View for PDLIM7 Gene
Genes around PDLIM7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q35.3 by Ensembl
- 5q35.3 by Entrez Gene
- 5q35.3 by HGNC
PDLIM7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PDLIM7 Gene
Proteins for PDLIM7 Gene
-
Protein details for PDLIM7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NR12-PDLI7_HUMAN
- Recommended name:
- PDZ and LIM domain protein 7
- Protein Accession:
- Q9NR12
- Q14250
- Q5XG82
- Q6NVZ5
- Q96C91
- Q9BXB8
- Q9BXB9
Protein attributes for PDLIM7 Gene
- Size:
- 457 amino acids
- Molecular mass:
- 49845 Da
- Quaternary structure:
-
- Binds via its LIM zinc-binding 3 domain (LIM 3) to endocytic codes of INSR, but not with those of IGF1R, LDLR, TFRC, or EGFR. Interacts with various PKC isoforms through the LIM zinc-binding domains. Binds to RET in a phosphorylation-independent manner via its LIM zinc-binding domain 2 (LIM 2). Probably part of a complex with SHC and the RET dimer. Interacts with TPM2. Interacts with TBX4 and TBX5 (By similarity).
- SequenceCaution:
-
- Sequence=AAC37565.1; Type=Frameshift; Positions=103, 128, 161, 183, 195, 245; Evidence={ECO:0000305};
Protein Expression for PDLIM7 Gene
Post-translational modifications for PDLIM7 Gene
Other Protein References for PDLIM7 Gene
Antibody Products
- Novus Biologicals Antibodies for PDLIM7
-
Abcam antibodies for PDLIM7
- Invitrogen Antibodies for PDLIM7
- Search GeneTex for Antibodies for PDLIM7
-
Santa Cruz Biotechnology (SCBT) Antibodies for PDLIM7
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for PDLIM7
- Origene Custom Protein Services for PDLIM7
- Search GeneTex for Proteins for PDLIM7
-
Abcam proteins for PDLIM7
Assay Products
No data available for DME Specific Peptides for PDLIM7 Gene
Domains & Families for PDLIM7 Gene
Gene Families for PDLIM7 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PDLIM7 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PDLIM7 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9NR12- Domain:
-
- The LIM zinc-binding 2 (LIM 2) domain interacts with TBX4.
- The LIM zinc-binding 3 (LIM 3) domain provides the structural basis for recognition of tyrosine-containing tight turn structures. This domain is necessary and sufficient for interaction with TBX5 (By similarity).
- Anchored to cell periphery via its N-terminal PDZ domain.
Function for PDLIM7 Gene
Molecular function for PDLIM7 Gene
- UniProtKB/Swiss-Prot Function:
- May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for PDLIM7 Gene
- MGI mutant phenotypes for PDLIM7:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for PDLIM7:
Animal Model Products
-
Taconic Biosciences Mouse Models for PDLIM7
- Cyagen custom Knockout/knockin (KOKI) mouse models for PDLIM7
-
-
ViGene Biosciences lentiviral particle packaged cDNA for PDLIM7 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PDLIM7 gene
- Search ViGene Biosciences for PDLIM7
CRISPR Products
-
OriGene CRISPR knockouts for PDLIM7
- genomics-online: gRNA clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
- Applied Biological Materials CRISPR for PDLIM7
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PDLIM7
- GenScript: Design CRISPR guide RNA sequences for PDLIM7
miRNA for PDLIM7 Gene
- miRTarBase miRNAs that target PDLIM7
miRNA Products
- Search ViGene Biosciences for PDLIM7
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for PDLIM7
- Browse OriGene Inhibitory RNA Products For PDLIM7
- genomics-online: shRNA clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PDLIM7 gene
Clone Products
-
OriGene ORF clones in human for PDLIM7
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PDLIM7
- VectorBuilder custom plasmid, inducible vectors for PDLIM7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PDLIM7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for PDLIM7
- Applied Biological Materials Clones for PDLIM7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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Horizon Cell Lines for PDLIM7
-
ViGene Biosciences adenoviral particle packaged cDNA for PDLIM7 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PDLIM7 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PDLIM7 gene
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PDLIM7 Gene
Localization for PDLIM7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PDLIM7 Gene
- Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity). {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 1 |
- Actin filaments (4)
- Focal adhesion sites (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001725 | stress fiber | IEA | -- |
| GO:0001726 | ruffle | IEA | -- |
| GO:0005634 | nucleus | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for PDLIM7 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | GDNF-Family Ligands and Receptor Interactions | ||
| 2 | Developmental Biology |
.51
|
|
| 3 | RET signaling |
.92
|
|
| 4 | EBV LMP1 signaling | ||
| 5 | Signaling events regulated by Ret tyrosine kinase | ||
Pathways by source for PDLIM7 Gene
2 BioSystems pathways for PDLIM7 Gene
3 Reactome pathways for PDLIM7 Gene
1 GeneGo (Thomson Reuters) pathway for PDLIM7 Gene
1 Qiagen pathway for PDLIM7 Gene
Interacting Proteins for PDLIM7 Gene
Selected Interacting proteins:
ENSP00000348099
Q9NR12-PDLI7_HUMAN
for PDLIM7 Gene via
STRING
MINT
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001503 | ossification | IEA | -- |
| GO:0006898 | receptor-mediated endocytosis | TAS | 7929196 |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0007411 | axon guidance | TAS | -- |
| GO:0030036 | actin cytoskeleton organization | IEA | -- |
No data available for SIGNOR curated interactions for PDLIM7 Gene
Transcripts for PDLIM7 Gene
mRNA/cDNA for PDLIM7 Gene
- (6) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (403) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for PDLIM7 Gene
CRISPR Products
-
OriGene CRISPR knockouts for PDLIM7
- genomics-online: gRNA clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
- Applied Biological Materials CRISPR for PDLIM7
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PDLIM7
- GenScript: Design CRISPR guide RNA sequences for PDLIM7
miRNA Products
- Search ViGene Biosciences for PDLIM7
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for PDLIM7
- Browse OriGene Inhibitory RNA Products For PDLIM7
- genomics-online: shRNA clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PDLIM7 gene
Clone Products
-
OriGene ORF clones in human for PDLIM7
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PDLIM7
- VectorBuilder custom plasmid, inducible vectors for PDLIM7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PDLIM7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for PDLIM7
- Applied Biological Materials Clones for PDLIM7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11a | · | 11b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: |
| ExUns: | 12a | · | 12b | ^ | 13 | ^ | 14 |
|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||
| SP2: | - | ||||||
| SP3: | - | ||||||
| SP4: | |||||||
| SP5: | |||||||
| SP6: | |||||||
| SP7: | |||||||
| SP8: | |||||||
| SP9: | |||||||
| SP10: | |||||||
| SP11: | |||||||
| SP12: | |||||||
| SP13: |
Expression for PDLIM7 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Cardiovascular System)
- Conventional Dendritic Cells I Spleen
- Granulocytes Peripheral Blood
- Spleen (Hematopoietic System)
-
Skeletal Muscle (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for PDLIM7 Gene
This gene is overexpressed in Colon - Sigmoid (x4.4) and Artery - Aorta (x4.2).
This gene is overexpressed in Urinary Bladder (10.2), Bone marrow stromal cell (9.3), Colon muscle (6.9), Prostate (6.7), and Rectum (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PDLIM7 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of PDLIM7 Gene:
PDLIM7SOURCE GeneReport for Unigene cluster for PDLIM7 Gene:
Hs.533040mRNA Expression by UniProt/SwissProt for PDLIM7 Gene:
Q9NR12-PDLI7_HUMAN
Tissue specificity:
Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver.
Evidence on tissue expression from TISSUES for PDLIM7 Gene
- Nervous system(4.7)
- Blood(4.5)
- Heart(4.4)
- Kidney(4.3)
- Liver(4.2)
- Muscle(3.1)
- Skin(2.9)
- Eye(2.4)
- Bone marrow(2.2)
- Lymph node(2.2)
- Lung(2.1)
Primer Products
-
OriGene qPCR primer pairs for PDLIM7
-
OriGene qPCR primer pairs and template standards for PDLIM7
- genomics-online: primer clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for PDLIM7 Gene
Orthologs for PDLIM7 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PDLIM7 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | PDLIM7 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | -- 34 |
|
OneToMany | |
| PDLIM7 33 |
|
||||
| -- 34 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Pdlim7 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Pdlim7 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | PDLIM7 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | PDLIM7 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | PDLIM7 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.15717 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | pdlim7 33 34 |
|
||
| zgc65907 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Zasp52 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | alp-1 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany |
- Species where no ortholog for PDLIM7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for PDLIM7 Gene
Paralogs for PDLIM7 Gene
(10) SIMAP similar genes for PDLIM7 Gene using alignment to 6 proteins:
Pseudogenes.org Pseudogenes for PDLIM7 Gene
Variants for PDLIM7 Gene
| SNP ID | Clin | Chr 05 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| VAR_036193 | A breast cancer sample | p.Lys450Asn | |||
| rs1000066525 | -- | 177,494,353(-) | C/G | intron_variant | |
| rs1000104763 | -- | 177,486,593(-) | T/C/G | genic_downstream_transcript_variant, intron_variant | |
| rs1000129710 | -- | 177,494,052(-) | G/C | intron_variant | |
| rs1000295178 | -- | 177,484,909(-) | C/T | genic_downstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1161311 | CNV | duplication | 26073780 |
Residual Variation Intolerance Score:
85% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.81;
66.96% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PDLIM7 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PDLIM7 Gene
Disorders for PDLIM7 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| pleural empyema |
|
|
| dental pulp calcification |
|
|
| bare lymphocyte syndrome, type i |
|
|
| pharynx cancer |
|
|
Search PDLIM7 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for PDLIM7
No data available for UniProtKB/Swiss-Prot and Genatlas for PDLIM7 Gene
Publications for PDLIM7 Gene
- Overexpressed LIM mineralization proteins do not require LIM domains to induce bone. (PMID: 11874232) Liu Y … Titus L (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002) 2 3 4 58
- Modeling and analysis of molecularinteraction between Smurf1-WW2 domain and various isoforms of LIM mineralization protein. (PMID: 17510966) Sangadala S … Reddy BV (Proteins 2007) 3 22 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- The PDZ domain of the LIM protein enigma binds to beta-tropomyosin. (PMID: 10359609) Guy PM … Gill GN (Molecular biology of the cell 1999) 3 4 58
- Shc and Enigma are both required for mitogenic signaling by Ret/ptc2. (PMID: 9528800) Durick K … Taylor SS (Molecular and cellular biology 1998) 3 4 58
Products for PDLIM7 Gene
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- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Taconic Biosciences Mouse Models for PDLIM7
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for PDLIM7
- Cyagen custom Knockout/knockin (KOKI) mouse models for PDLIM7
- VectorBuilder custom plasmid, inducible vectors for PDLIM7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PDLIM7
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for PDLIM7
- antibodies-online: Search results for 59 available PDLIM7 Antibodies ranked by validation data
- Compare Top PDLIM7 Antibodies
- antibodies-online: Search results for 13 available PDLIM7 Elisa Kits ranked by validation data
- Compare Top PDLIM7 Elisa Kits
- Quality Products:
- antibodies-online: Search results for 15 available PDLIM7 Proteins ranked by validation data
- Compare Top PDLIM7 Proteins
- Quality Products:
- Search GeneTex for Antibodies for PDLIM7
- Search GeneTex for Proteins for PDLIM7
- ViGene Biosciences adenoviral particle packaged cDNA for PDLIM7 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PDLIM7 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PDLIM7 gene
- Search ViGene Biosciences for PDLIM7
- Santa Cruz Biotechnology (SCBT) Antibodies for PDLIM7
- Search Santa Cruz Biotechnology (SCBT) for PDLIM7 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PDLIM7
- Horizon Cell Lines for PDLIM7
- genomics-online: cdna clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
- orf clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
- genomics-online: gRNA clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
- genomics-online: primer clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
- genomics-online: shRNA clones - Search results for 163 available PDLIM7 gene related products
- Overview of 163 available PDLIM7 gene related products
Sources for PDLIM7 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
