Aliases for PDE7B Gene
External Ids for PDE7B Gene
Previous GeneCards Identifiers for PDE7B Gene
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.[provided by RefSeq, Apr 2009]
GeneCards Summary for PDE7B Gene
PDE7B (Phosphodiesterase 7B) is a Protein Coding gene. Diseases associated with PDE7B include Dyslexia and Joubert Syndrome 3. Among its related pathways are Signaling by GPCR and Metabolism. Gene Ontology (GO) annotations related to this gene include 3',5'-cyclic-nucleotide phosphodiesterase activity and 3',5'-cyclic-AMP phosphodiesterase activity. An important paralog of this gene is PDE7A.
UniProtKB/Swiss-Prot Summary for PDE7B Gene
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.