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Aliases for PCM1 Gene

Aliases for PCM1 Gene

  • Pericentriolar Material 1 2 3 5
  • HPCM-1 3 4
  • PCM-1 3 4
  • Pericentriolar Material 1 Protein 3
  • Pericentriolar Material 1, PCM1 3
  • RET/PCM-1 3
  • PTC4 3

External Ids for PCM1 Gene

Previous GeneCards Identifiers for PCM1 Gene

  • GC08P017656
  • GC08P017843
  • GC08P017790
  • GC08P017824
  • GC08P016324
  • GC08P017781

Summaries for PCM1 Gene

Entrez Gene Summary for PCM1 Gene

  • The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

GeneCards Summary for PCM1 Gene

PCM1 (Pericentriolar Material 1) is a Protein Coding gene. Diseases associated with PCM1 include Differentiated Thyroid Carcinoma and Thyroid Cancer, Nonmedullary, 1. Among its related pathways are Organelle biogenesis and maintenance and Regulation of PLK1 Activity at G2/M Transition. Gene Ontology (GO) annotations related to this gene include identical protein binding.

UniProtKB/Swiss-Prot for PCM1 Gene

  • Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. Required to anchor microtubules to the centrosome. Involved in the biogenesis of cilia.

Gene Wiki entry for PCM1 Gene

Additional gene information for PCM1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PCM1 Gene

Genomics for PCM1 Gene

GeneHancer (GH) Regulatory Elements for PCM1 Gene

Promoters and enhancers for PCM1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I017921 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 567.7 +2.6 2582 8.1 MLX DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 ZNF610 GLIS1 PCM1 ENSG00000253671 MTUS1 ASAH1 FGL1 SLC7A2 GC08P017880 LOC101929066
GH08I017613 Enhancer 1.4 Ensembl ENCODE dbSUPER 23.6 -306.0 -306035 7.6 FOXA2 MLX ZFP64 ARID4B FEZF1 DMAP1 SLC30A9 ZNF213 SP3 SP5 MICU3 PCM1 PDGFRL ENSG00000249258 MTUS1 FGF20 ENSG00000277466 MIR548V
GH08I017915 Enhancer 1.3 Ensembl ENCODE dbSUPER 17.5 -6.4 -6402 1.5 FOXA2 MLX ZFP64 ARID4B DMAP1 ZNF48 ETS1 PAF1 SP5 MXD4 PCM1 ENSG00000253671 MTUS1 ASAH1 FGL1 GC08P017880
GH08I017912 Enhancer 0.9 Ensembl ENCODE 14.9 -10.0 -9950 0.6 CTCF SAP130 ZNF2 DNMT3B RAD21 RFX5 RELA HIC1 ZNF335 GLIS2 PCM1 ASAH1 ENSG00000253671 FGL1 GC08P017880
GH08I017255 Enhancer 0.8 ENCODE 15.4 -666.8 -666787 1.1 HDAC1 ZSCAN4 ZFP64 FEZF1 ZNF335 EGR1 ZNF362 PHF21A CEBPB ZC3H11A PCM1 ZDHHC2 MICU3 CNOT7 VPS37A LOC102724838
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around PCM1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the PCM1 gene promoter:

Genomic Locations for PCM1 Gene

Genomic Locations for PCM1 Gene
chr8:17,922,840-18,029,948
(GRCh38/hg38)
Size:
107,109 bases
Orientation:
Plus strand
chr8:17,780,349-17,887,457
(GRCh37/hg19)

Genomic View for PCM1 Gene

Genes around PCM1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PCM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PCM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PCM1 Gene

Proteins for PCM1 Gene

  • Protein details for PCM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15154-PCM1_HUMAN
    Recommended name:
    Pericentriolar material 1 protein
    Protein Accession:
    Q15154
    Secondary Accessions:
    • Q58F13
    • Q6P1K7
    • Q8NB85
    • Q9BWC1
    • Q9H4A2

    Protein attributes for PCM1 Gene

    Size:
    2024 amino acids
    Molecular mass:
    228533 Da
    Quaternary structure:
    • Self-associates. Interacts with C2CD3 (By similarity). Interacts with BBS4, BBS8, CETN3, HAP1, NDE1, NDEL1, MAP1LC3B, GABARAPAL2, and GABARAP. Interacts with CEP131; the interaction increases in response to ultraviolet light (UV) radiation. Associates with microtubule; association to microtubule is reduced in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock, in a process that requires p38 MAP kinase signaling. Interacts with CCDC113. Interacts with SSX2IP (By similarity). Interacts with CCDC13 (PubMed:24816561). Interacts with CEP290 (By similarity). Interacts with PARD6A (PubMed:20719959). Interacts with KIAA0753/OFIP, FOPNL/FOR20 and OFD1; the interaction with FOPNL/FOR20 and OFD1 may be mediated by KIAA0753/OFIP (PubMed:26643951).
    SequenceCaution:
    • Sequence=AAH27477.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAH65022.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAC03656.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAC14882.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence.; Evidence={ECO:0000305};

    Alternative splice isoforms for PCM1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PCM1 Gene

Post-translational modifications for PCM1 Gene

  • Ubiquitinated. Undergoes monoubiquitination catalyzed by the E3 ubiquitin-protein ligase MIB1 in proliferating cells, preventing cilia formation. Monoubiquitination by MIB1 is inhibited in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock, resulting in cilia formation initiation.
  • Ubiquitination at isoforms=2, 351, Lys104, Lys139, Lys152, Lys218, isoforms=2, 3229, Lys255, Lys393, Lys399, Lys409, Lys412, Lys658, isoforms=2738, Lys762, isoforms=2786, isoforms=2787, Lys807, Lys841, Lys954, Lys970, Lys996, Lys1076, Lys1181, Lys1197, isoforms=21198, Lys1221, isoforms=21225, isoforms=21234, Lys1329, isoforms=1345, Lys1531, isoforms=21602, isoforms=21647, isoforms=21659, and isoforms=21701

No data available for DME Specific Peptides for PCM1 Gene

Domains & Families for PCM1 Gene

Gene Families for PCM1 Gene

Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Predicted intracellular proteins

Protein Domains for PCM1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q15154

UniProtKB/Swiss-Prot:

PCM1_HUMAN :
  • Belongs to the PCM1 family.
Family:
  • Belongs to the PCM1 family.
genes like me logo Genes that share domains with PCM1: view

Function for PCM1 Gene

Molecular function for PCM1 Gene

GENATLAS Biochemistry:
pericentriolar material 1
UniProtKB/Swiss-Prot Function:
Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. Required to anchor microtubules to the centrosome. Involved in the biogenesis of cilia.
UniProtKB/Swiss-Prot Induction:
Expression is reduced in breast and ovarian cancer.

Phenotypes From GWAS Catalog for PCM1 Gene

Gene Ontology (GO) - Molecular Function for PCM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 9361024
GO:0042802 identical protein binding ISS --
genes like me logo Genes that share ontologies with PCM1: view
genes like me logo Genes that share phenotypes with PCM1: view

Animal Model Products

CRISPR Products

miRNA for PCM1 Gene

miRTarBase miRNAs that target PCM1

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PCM1 Gene

Localization for PCM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PCM1 Gene

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic granule. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=Recruitment to the centrosome requires microtubules and dynein. The majority of the protein dissociates from the centrosome during metaphase and subsequently localizes to the cleavage site in telophase. Displaced from centriolar satellites and centrosome in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock, in a process that requires p38 MAP kinase signaling.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PCM1 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 5

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (4)
  • Cytosol (2)
  • Nuclear membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for PCM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000242 pericentriolar material ISS,IEA --
GO:0005737 cytoplasm TAS,ISS --
GO:0005813 centrosome ISS,IEA --
GO:0005814 centriole IEA --
GO:0005815 microtubule organizing center IEA --
genes like me logo Genes that share ontologies with PCM1: view

Pathways & Interactions for PCM1 Gene

genes like me logo Genes that share pathways with PCM1: view

Pathways by source for PCM1 Gene

SIGNOR curated interactions for PCM1 Gene

Gene Ontology (GO) - Biological Process for PCM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000086 G2/M transition of mitotic cell cycle TAS --
GO:0001764 neuron migration IEA --
GO:0007098 centrosome cycle IMP 17574030
GO:0010389 regulation of G2/M transition of mitotic cell cycle TAS --
GO:0022027 interkinetic nuclear migration IEA,ISS --
genes like me logo Genes that share ontologies with PCM1: view

Drugs & Compounds for PCM1 Gene

(1) Drugs for PCM1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
genes like me logo Genes that share compounds with PCM1: view

Transcripts for PCM1 Gene

Unigene Clusters for PCM1 Gene

Pericentriolar material 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for PCM1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ^ 12a · 12b ^ 13a ·
SP1:
SP2:
SP3:
SP4:
SP5:
SP6: - -
SP7: -
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15: - - - - - - - - - - -
SP16:
SP17:
SP18:
SP19:
SP20:
SP21: - - -
SP22:
SP23:

ExUns: 13b ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19 ^ 20a · 20b · 20c ^ 21a · 21b · 21c ^ 22 ^ 23a · 23b ^ 24a · 24b ^ 25a · 25b · 25c · 25d ^ 26a · 26b ^
SP1: - -
SP2: - - - - - - - - - - - -
SP3:
SP4: -
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12: -
SP13:
SP14:
SP15:
SP16:
SP17:
SP18: -
SP19:
SP20: -
SP21:
SP22:
SP23:

ExUns: 27 ^ 28a · 28b ^ 29 ^ 30a · 30b ^ 31 ^ 32a · 32b ^ 33 ^ 34a · 34b ^ 35 ^ 36a · 36b ^ 37 ^ 38a · 38b ^ 39 ^ 40 ^ 41 ^ 42 ^ 43
SP1: - - - -
SP2: - - - - - - - - - - - - - - - - -
SP3:
SP4: - - -
SP5: - -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12: -
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20: - - -
SP21:
SP22:
SP23:

Relevant External Links for PCM1 Gene

GeneLoc Exon Structure for
PCM1
ECgene alternative splicing isoforms for
PCM1

Expression for PCM1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PCM1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for PCM1 Gene

This gene is overexpressed in Plasma (32.6) and Testis (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PCM1 Gene



Protein tissue co-expression partners for PCM1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PCM1 Gene:

PCM1

SOURCE GeneReport for Unigene cluster for PCM1 Gene:

Hs.491148

mRNA Expression by UniProt/SwissProt for PCM1 Gene:

Q15154-PCM1_HUMAN
Tissue specificity: Expressed in blood, bone marrow, breast, lymph node, ovary and thyroid.

Evidence on tissue expression from TISSUES for PCM1 Gene

  • Nervous system(4.8)
  • Liver(4.4)
  • Lung(4.4)
  • Muscle(2.2)
  • Thyroid gland(2.1)
  • Heart(2)
  • Spleen(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for PCM1 Gene

Germ Layers:
  • endoderm
Systems:
  • endocrine
Regions:
Head and neck:
  • neck
  • thyroid
genes like me logo Genes that share expression patterns with PCM1: view

Primer Products

No data available for mRNA differential expression in normal tissues for PCM1 Gene

Orthologs for PCM1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PCM1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PCM1 33 34
  • 99.52 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 92 (a)
OneToMany
-- 34
  • 75 (a)
OneToMany
-- 34
  • 65 (a)
OneToMany
-- 34
  • 59 (a)
OneToMany
dog
(Canis familiaris)
Mammalia PCM1 33 34
  • 91.92 (n)
cow
(Bos Taurus)
Mammalia PCM1 33 34
  • 90.15 (n)
mouse
(Mus musculus)
Mammalia Pcm1 33 16 34
  • 88.94 (n)
rat
(Rattus norvegicus)
Mammalia Pcm1 33
  • 88.31 (n)
oppossum
(Monodelphis domestica)
Mammalia PCM1 34
  • 74 (a)
OneToOne
chicken
(Gallus gallus)
Aves PCM1 33 34
  • 72.96 (n)
lizard
(Anolis carolinensis)
Reptilia PCM1 34
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia pcm1 33
  • 67.96 (n)
Str.18845 33
African clawed frog
(Xenopus laevis)
Amphibia pcm-1 33
zebrafish
(Danio rerio)
Actinopterygii pcm1 33 34
  • 59.54 (n)
Species where no ortholog for PCM1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for PCM1 Gene

ENSEMBL:
Gene Tree for PCM1 (if available)
TreeFam:
Gene Tree for PCM1 (if available)

Paralogs for PCM1 Gene

No data available for Paralogs for PCM1 Gene

Variants for PCM1 Gene

Sequence variations from dbSNP and Humsavar for PCM1 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1085307084 uncertain-significance, Nonmedullary thyroid carcinoma 1 17,966,078(+) C/T coding_sequence_variant, stop_gained
rs1000014797 -- 18,025,310(+) A/T genic_downstream_transcript_variant, intron_variant
rs1000023189 -- 17,955,912(+) A/C intron_variant
rs1000031521 -- 17,994,173(+) C/T genic_downstream_transcript_variant, intron_variant
rs1000058874 -- 17,951,923(+) AAAAAAAA/AAAAAAAAA intron_variant

Structural Variations from Database of Genomic Variants (DGV) for PCM1 Gene

Variant ID Type Subtype PubMed ID
nsv610701 CNV gain 21841781
nsv524215 CNV gain 19592680
nsv522647 CNV loss 19592680
nsv1116572 OTHER inversion 24896259
esv3891365 CNV gain 25118596
esv3616509 CNV loss 21293372
esv3616500 CNV gain 21293372
esv3572605 CNV loss 25503493
esv3543161 CNV deletion 23714750
esv2762735 CNV gain 21179565
esv2736700 CNV deletion 23290073
esv2676396 CNV deletion 23128226
dgv7123n100 CNV gain 25217958
dgv7121n100 CNV gain 25217958

Variation tolerance for PCM1 Gene

Residual Variation Intolerance Score: 92.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.17; 92.37% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PCM1 Gene

Human Gene Mutation Database (HGMD)
PCM1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
PCM1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PCM1 Gene

Disorders for PCM1 Gene

MalaCards: The human disease database

(6) MalaCards diseases for PCM1 Gene - From: HGMD, GTR, Orphanet, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
differentiated thyroid carcinoma
  • papillary or follicular thyroid carcinoma
thyroid cancer, nonmedullary, 1
  • nmtc1
atypical chronic myeloid leukemia
  • acml
occult macular dystrophy
  • ocmd
bardet-biedl syndrome 4
  • bbs4
- elite association - COSMIC cancer census association via MalaCards
Search PCM1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

PCM1_HUMAN
  • Note=A chromosomal aberration involving PCM1 is found in a variety of hematological malignancies including atypical chronic myeloid leukemia (atypical CML) and T-cell lymphoma. Translocation t(8;9)(p22;p24) with JAK2 links the protein kinase domain of JAK2 to the major portion of PCM1.
  • Note=A chromosomal aberration involving PCM1 is found in papillary thyroid carcinomas (PTCs). Translocation t(8;10)(p21.3;q11.2) with RET links the protein kinase domain of RET to the major portion of PCM1. {ECO:0000269 PubMed:10980597}.

Additional Disease Information for PCM1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with PCM1: view

No data available for Genatlas for PCM1 Gene

Publications for PCM1 Gene

  1. Dynamic recruitment of Nek2 kinase to the centrosome involves microtubules, PCM-1, and localized proteasomal degradation. (PMID: 15659651) Hames RS … Fry AM (Molecular biology of the cell 2005) 2 3 4 22 58
  2. PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution. (PMID: 8120099) Balczon R … Zimmer WE (The Journal of cell biology 1994) 2 3 4 22 58
  3. Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle. (PMID: 16943179) Srsen V … Merdes A (The Journal of cell biology 2006) 3 4 22 58
  4. Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly. (PMID: 16291865) Guo J … Zhu X (Molecular biology of the cell 2006) 3 4 22 58
  5. The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene. (PMID: 16091753) Bousquet M … Brousset P (Oncogene 2005) 3 4 22 58

Products for PCM1 Gene

Sources for PCM1 Gene

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