Aliases for PCAT4 Gene

Subcategory (RNA class) for PCAT4 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for PCAT4 Gene

  • Prostate Cancer Associated Transcript 4 2 3 5
  • Prostate Cancer Associated Transcript 4 (Non-Protein Coding) 2 3
  • Gene Differentially Expressed In Prostate 2 3
  • Prostate Cancer Gene 1 2 3
  • PCAT4 2 168
  • NONHSAG038300 92
  • HSALNG0035451 167
  • PCAN1 3
  • GDEP 3
  • PCA4 3

External Ids for PCAT4 Gene

Previous GeneCards Identifiers for PCAT4 Gene

  • GC04P080750

Summaries for PCAT4 Gene

GeneCards Summary for PCAT4 Gene

PCAT4 (Prostate Cancer Associated Transcript 4) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with PCAT4 include Primary Cutaneous Amyloidosis and Cardiomyopathy, Familial Hypertrophic, 1.

Additional gene information for PCAT4 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PCAT4 Gene

Genomics for PCAT4 Gene

GeneHancer (GH) Regulatory Elements for PCAT4 Gene

Promoters and enhancers for PCAT4 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J079851 Enhancer 1 Ensembl ENCODE 11.8 +24.8 24846 1 GTF2E2 ZIC2 MYC CTBP1 TEAD1 FOXA2 TRIM24 CEBPG FOS MAX PCAT4 ENSG00000212620 HSALNG0035454
GH04J079649 Enhancer 0.9 Ensembl ENCODE 10.5 -175.3 -175310 4.5 ZNF639 TRIM28 TEAD1 OSR2 NR2F2 WT1 FOS NANOG CEBPB KLF8 PCAT4 LINC00989 ANTXR2 LINC02469 HSALNG0035441
GH04J079575 Enhancer 0.8 Ensembl ENCODE 9.7 -251.6 -251582 1.8 EP300 CTCF REST RAD21 TRIM22 SMC3 CEBPG MAX SPI1 TAL1 LINC00989 PCAT4 OR7E94P lnc-GK2-1 piR-32559-317
GH04J079906 Enhancer 0.6 Ensembl 11.1 +80.0 80030 2.6 PBX2 NR2F1 CEBPG ATF4 NR2F6 MEIS2 ZBTB40 ATF3 NR2C1 PKNOX1 PCAT4 ANTXR2 LINC00989 HSALNG0035454 piR-48772-018 lnc-ANTXR2-3
GH04J079385 Enhancer 0.6 UCNEbase dbSUPER 9.5 -441.6 -441621 0.3 FOS lnc-BMP2K-2 PCAT4 LOC105377300 lnc-BMP2K-7 LINC01088
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PCAT4 on UCSC Golden Path with GeneCards custom track

Genomic Locations for PCAT4 Gene

Genomic Locations for PCAT4 Gene
chr4:79,827,471-79,877,771
(GRCh38/hg38)
Size:
50,301 bases
Orientation:
Plus strand
chr4:80,748,625-80,798,924
(GRCh37/hg19)
Size:
50,300 bases
Orientation:
Plus strand

Genomic View for PCAT4 Gene

Genes around PCAT4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PCAT4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PCAT4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PCAT4 Gene

Proteins for PCAT4 Gene

Post-translational modifications for PCAT4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PCAT4 Gene

Domains & Families for PCAT4 Gene

Gene Families for PCAT4 Gene

Suggested Antigen Peptide Sequences for PCAT4 Gene

GenScript: Design optimal peptide antigens:
  • Prostate cancer protein 1 (GDEP_HUMAN)
genes like me logo Genes that share domains with PCAT4: view

No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PCAT4 Gene

Function for PCAT4 Gene

Phenotypes From GWAS Catalog for PCAT4 Gene

genes like me logo Genes that share phenotypes with PCAT4: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PCAT4 Gene

Localization for PCAT4 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PCAT4 gene
Compartment Confidence
cytoskeleton 2
endoplasmic reticulum 2
plasma membrane 1
extracellular 1
mitochondrion 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PCAT4 Gene

Pathways & Interactions for PCAT4 Gene

PathCards logo

SuperPathways for PCAT4 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for PCAT4 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PCAT4 Gene

Drugs & Compounds for PCAT4 Gene

No Compound Related Data Available

Transcripts for PCAT4 Gene

mRNA/cDNA for PCAT4 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
5 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 NONCODE transcripts :
2 LncBook transcripts :
2 LNCipedia transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for PCAT4 Gene

No ASD Table

Relevant External Links for PCAT4 Gene

GeneLoc Exon Structure for
PCAT4

Expression for PCAT4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PCAT4 Gene

mRNA differential expression in normal tissues according to GTEx for PCAT4 Gene

This gene is overexpressed in Prostate (x51.4).

Protein differential expression in normal tissues from HIPED for PCAT4 Gene

This gene is overexpressed in Liver (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for PCAT4 Gene



Protein tissue co-expression partners for PCAT4 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PCAT4

Evidence on tissue expression from TISSUES for PCAT4 Gene

  • Muscle(2.4)
genes like me logo Genes that share expression patterns with PCAT4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PCAT4 Gene

Orthologs for PCAT4 Gene

Evolution for PCAT4 Gene

ENSEMBL:
Gene Tree for PCAT4 (if available)
TreeFam:
Gene Tree for PCAT4 (if available)

No data available for Orthologs for PCAT4 Gene

Paralogs for PCAT4 Gene

No data available for Paralogs for PCAT4 Gene

Variants for PCAT4 Gene

Additional dbSNP identifiers (rs#s) for PCAT4 Gene

Structural Variations from Database of Genomic Variants (DGV) for PCAT4 Gene

Variant ID Type Subtype PubMed ID
esv2486950 CNV insertion 19546169
nsv1006026 CNV loss 25217958
nsv829983 CNV gain 17160897

Additional Variant Information for PCAT4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PCAT4

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for PCAT4 Gene

Disorders for PCAT4 Gene

MalaCards: The human disease database

(3) MalaCards diseases for PCAT4 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
primary cutaneous amyloidosis
  • pca
cardiomyopathy, familial hypertrophic, 1
  • fhc
prostate cancer
  • prostate cancer, somatic
- elite association - COSMIC cancer census association via MalaCards
Search PCAT4 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for PCAT4

genes like me logo Genes that share disorders with PCAT4: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PCAT4 Gene

Publications for PCAT4 Gene

  1. Expression and initial promoter characterization of PCAN1 in retinal tissue and prostate cell lines. (PMID: 15299187) Cross D … Burmester JK (Medical oncology (Northwood, London, England) 2004) 2 3 23 54
  2. Characterization of two functional NKX3.1 binding sites upstream of the PCAN1 gene that are involved in the positive regulation of PCAN1 gene transcription. (PMID: 18454873) Liu W … Jiang A (BMC molecular biology 2008) 2 3 54
  3. Molecular cloning and analysis of the human PCAN1 (GDEP) promoter. (PMID: 17468839) Liu W … Jiang A (Cellular & molecular biology letters 2007) 3 23 54
  4. GDEP, a new gene differentially expressed in normal prostate and prostate cancer. (PMID: 11536302) Olsson P … Pastan I (The Prostate 2001) 2 3 54
  5. Functional characterization of the GDEP promoter and three enhancer elements in retinoblastoma and prostate cell lines. (PMID: 18188713) Cross DS … Burmester JK (Medical oncology (Northwood, London, England) 2008) 3 54

Products for PCAT4 Gene

Sources for PCAT4 Gene