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Aliases for PCAT18 Gene

Subcategory (RNA class) for PCAT18 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for PCAT18 Gene

  • Prostate Cancer Associated Transcript 18 2 3
  • Prostate Cancer Associated Transcript 18 (Non-Protein Coding) 2 3 5
  • Long Intergenic Non-Protein Coding RNA 1092 2 3
  • LINC01092 3

External Ids for PCAT18 Gene

Previous GeneCards Identifiers for PCAT18 Gene

  • GC18M024268

Summaries for PCAT18 Gene

GeneCards Summary for PCAT18 Gene

PCAT18 (Prostate Cancer Associated Transcript 18) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with PCAT18 include Prostate Cancer.

Additional gene information for PCAT18 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PCAT18 Gene

Genomics for PCAT18 Gene

GeneHancer (GH) Regulatory Elements for PCAT18 Gene

Promoters and enhancers for PCAT18 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J026703 Promoter/Enhancer 1.1 EPDnew ENCODE dbSUPER 650.7 -0.1 -65 0.2 NFE2 ZBTB40 ZBTB20 PCAT18 KCTD1 AQP4-AS1 GC18P026799
GH18J026701 Enhancer 0.7 Ensembl ENCODE dbSUPER 663.8 +1.5 1479 0.7 ZNF512 PCAT18 KCTD1 GC18M026690 ENSG00000275900 AQP4-AS1
GH18J026702 Enhancer 0.5 ENCODE dbSUPER 650.7 +0.8 845 0.2 ZNF512 PCAT18 GC18M026690 ENSG00000275900 AQP4-AS1
GH18J026740 Promoter/Enhancer 0.9 EPDnew ENCODE 69.7 -37.9 -37901 1.7 MAFF CEBPB MAFK KCTD1 PCAT18 GC18P026799 AQP4-AS1
GH18J026655 Promoter/Enhancer 2 EPDnew Ensembl ENCODE dbSUPER 9.4 +46.8 46778 2.6 ZSCAN4 MZF1 SIN3A ZNF48 YY1 ZNF335 SP3 ZBTB11 ZNF398 ZEB2 KCTD1 AQP4-AS1 PCAT18 LOC102725227
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PCAT18 on UCSC Golden Path with GeneCards custom track

Genomic Locations for PCAT18 Gene

Genomic Locations for PCAT18 Gene
chr18:26,687,621-26,703,638
(GRCh38/hg38)
Size:
16,018 bases
Orientation:
Minus strand
chr18:24,267,585-24,283,602
(GRCh37/hg19)
Size:
16,018 bases
Orientation:
Minus strand

Genomic View for PCAT18 Gene

Genes around PCAT18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PCAT18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PCAT18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PCAT18 Gene

Proteins for PCAT18 Gene

Post-translational modifications for PCAT18 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PCAT18 Gene

Domains & Families for PCAT18 Gene

Gene Families for PCAT18 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PCAT18: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PCAT18 Gene

Function for PCAT18 Gene

Phenotypes From GWAS Catalog for PCAT18 Gene

Phenotypes for PCAT18 Gene

genes like me logo Genes that share phenotypes with PCAT18: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PCAT18 Gene

Localization for PCAT18 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PCAT18 gene
Compartment Confidence
endosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PCAT18 Gene

Pathways & Interactions for PCAT18 Gene

SuperPathways for PCAT18 Gene

No Data Available

Interacting Proteins for PCAT18 Gene

Gene Ontology (GO) - Biological Process for PCAT18 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PCAT18 Gene

Drugs & Compounds for PCAT18 Gene

No Compound Related Data Available

Transcripts for PCAT18 Gene

mRNA/cDNA for PCAT18 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(1) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for PCAT18 Gene

No ASD Table

Relevant External Links for PCAT18 Gene

GeneLoc Exon Structure for
PCAT18
ECgene alternative splicing isoforms for
PCAT18

Expression for PCAT18 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PCAT18 Gene

mRNA differential expression in normal tissues according to GTEx for PCAT18 Gene

This gene is overexpressed in Minor Salivary Gland (x8.7), Prostate (x5.0), and Stomach (x4.9).

NURSA nuclear receptor signaling pathways regulating expression of PCAT18 Gene:

PCAT18
genes like me logo Genes that share expression patterns with PCAT18: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PCAT18 Gene

Orthologs for PCAT18 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PCAT18 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U3 34
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia U3 34 34 34 34 34 34 34 34 34
  • 68 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia U3 34 34 34 34 34 34 34 34
  • 64 (a)
ManyToMany
chicken
(Gallus gallus)
Aves U3 34 34 34
  • 60 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia U3 34
  • 59 (a)
OneToMany
Species where no ortholog for PCAT18 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PCAT18 Gene

ENSEMBL:
Gene Tree for PCAT18 (if available)
TreeFam:
Gene Tree for PCAT18 (if available)

Paralogs for PCAT18 Gene

No data available for Paralogs for PCAT18 Gene

Variants for PCAT18 Gene

Sequence variations from dbSNP and Humsavar for PCAT18 Gene

SNP ID Clin Chr 18 pos Variation AA Info Type
rs1000172921 -- 26,694,310(-) A/G intron_variant
rs1000199479 -- 26,690,524(-) A/ intron_variant
rs1000325561 -- 26,699,994(-) G/T intron_variant
rs1000384786 -- 26,687,782(-) T/C non_coding_transcript_variant
rs1000438549 -- 26,688,086(-) G/C non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for PCAT18 Gene

Variant ID Type Subtype PubMed ID
esv2761995 CNV loss 21179565

Additional Variant Information for PCAT18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PCAT18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PCAT18 Gene

Disorders for PCAT18 Gene

MalaCards: The human disease database

(1) MalaCards diseases for PCAT18 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
prostate cancer
  • prostate cancer, susceptibility to
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for PCAT18

genes like me logo Genes that share disorders with PCAT18: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PCAT18 Gene

Publications for PCAT18 Gene

  1. Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer. (PMID: 24519926) Crea F … Helgason CD (Oncotarget 2014) 2 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  3. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 58

Products for PCAT18 Gene

Sources for PCAT18 Gene

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