Aliases for PCAT18 Gene

Subcategory (RNA class) for PCAT18 Gene

lncRNA

Number of RNA Genes sources:

5 / 17

Aliases for PCAT18 Gene

  • Prostate Cancer Associated Transcript 18 2 3 5
  • PCAT18 2 5 165
  • Prostate Cancer Associated Transcript 18 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 1092 2 3
  • LINC01092 2 3
  • NONHSAG023598.2 91
  • HSALNG0120583 164
  • SNORD3@L29 170
  • SNODB1379 177

External Ids for PCAT18 Gene

Previous GeneCards Identifiers for PCAT18 Gene

  • GC18M024268

Summaries for PCAT18 Gene

GeneCards Summary for PCAT18 Gene

PCAT18 (Prostate Cancer Associated Transcript 18) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with PCAT18 include Prostate Cancer and Renal Cell Carcinoma, Nonpapillary.

Rfam classification for PCAT18 Gene

Additional gene information for PCAT18 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for PCAT18 Gene

Genomics for PCAT18 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PCAT18 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J026703 Promoter/Enhancer 0.9 EPDnew ENCODE dbSUPER 600.3 +38.1 38095 0.2 ZBTB20 NFE2 ZBTB40 PCAT18 KCTD1 RF00017-2646 ENSG00000275900 AQP4-AS1 AQP4
GH18J026740 Promoter/Enhancer 0.7 EPDnew ENCODE 670.1 +0.3 259 1.7 CEBPB MAFK MAFF PCAT18 KCTD1 piR-48325-075 AQP4-AS1 AQP4
GH18J026655 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 9.7 +85.1 85079 4.2 PRDM10 ZNF692 PRDM1 ZIC2 ZSCAN4 POLR2A PATZ1 ZNF501 EZH2 CTCF AQP4-AS1 KCTD1 lnc-AQP4-2 PCAT18 LOC102725227 TAF4B
GH18J026744 Enhancer 0.9 ENCODE CraniofacialAtlas 15.7 -4.9 -4861 3.5 CEBPG PRDM10 FOXA1 RXRB SP1 CTBP1 FOXA2 CEBPB USF1 YY1 PCAT18 KCTD1 AQP4-AS1 lnc-TAF4B-10 lnc-KCTD1-2 AQP4
GH18J026752 Enhancer 0.9 Ensembl ENCODE 14.2 -10.9 -10902 1.4 RELA IKZF2 CEBPB ARID3A DPF2 RELB RUNX3 GATAD2B YY1 BCL11A lnc-KCTD1-2 PCAT18 lnc-TAF4B-10 KCTD1 AQP4-AS1 AQP4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PCAT18 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for PCAT18 Gene

Genomic Locations for PCAT18 Gene
chr18:26,668,232-26,741,798
(GRCh38/hg38)
Size:
73,567 bases
Orientation:
Minus strand
chr18:24,267,585-24,283,602
(GRCh37/hg19)
Size:
16,018 bases
Orientation:
Minus strand

Genomic View for PCAT18 Gene

Genes around PCAT18 on UCSC Golden Path with GeneCards custom track
PCAT18 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
PCAT18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PCAT18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PCAT18 Gene

Proteins for PCAT18 Gene

Post-translational modifications for PCAT18 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PCAT18 Gene

Domains & Families for PCAT18 Gene

Gene Families for PCAT18 Gene

genes like me logo Genes that share domains with PCAT18: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PCAT18 Gene

Function for PCAT18 Gene

Phenotypes From GWAS Catalog for PCAT18 Gene

Phenotypes for PCAT18 Gene

genes like me logo Genes that share phenotypes with PCAT18: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PCAT18 Gene

Localization for PCAT18 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PCAT18 gene
Compartment Confidence
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for PCAT18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with PCAT18: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for PCAT18 Gene

Pathways & Interactions for PCAT18 Gene

PathCards logo

SuperPathways for PCAT18 Gene

No Data Available

Gene Ontology (GO) - Biological Process for PCAT18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with PCAT18: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PCAT18 Gene

Drugs & Compounds for PCAT18 Gene

No Compound Related Data Available

Transcripts for PCAT18 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for PCAT18 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000016073B_9606 lncRNA 2598 6

HGNC: 49211,

RefSeq: NR_024259,

Ensembl: ENST00000579458 (view in UCSC) ,

LncBook: HSALNT0249183,

LNCipedia: PCAT18:1, PCAT18:4,

NONCODE: NONHSAT058756.2,

URS00008161A1_9606 snoRNA 213 3

LNCipedia: PCAT18:2,

snoDB: SNODB1379,

snOPY: Homo_sapiens300212,

URS00009B586A_9606 lncRNA 898 2

LncBook: HSALNT0249188,

NONCODE: NONHSAT178303.1,

URS0000D5B034_9606 lncRNA 305 2

LncBook: HSALNT0249190,

LNCipedia: PCAT18:5,

URS0000EB6699_9606 lncRNA 2600 1

LncBook: HSALNT0289205,

PCAT18 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for PCAT18 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for PCAT18 Gene

No ASD Table

Relevant External Links for PCAT18 Gene

GeneLoc Exon Structure for
PCAT18

Expression for PCAT18 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PCAT18 Gene

mRNA differential expression in normal tissues according to GTEx for PCAT18 Gene

This gene is overexpressed in Minor Salivary Gland (x8.7), Prostate (x5.0), and Stomach (x4.9).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PCAT18

genes like me logo Genes that share expression patterns with PCAT18: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PCAT18 Gene

Orthologs for PCAT18 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PCAT18 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia U3 31
  • 99 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia U3 31 31 31 31 31 31 31 31 31
  • 67 (a)
ManyToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia U3 31 31 31 31 31 31 31 31
  • 62 (a)
ManyToMany
Chicken
(Gallus gallus)
Aves U3 31 31 31
  • 60 (a)
ManyToMany
Lizard
(Anolis carolinensis)
Reptilia U3 31
  • 59 (a)
OneToMany
Species where no ortholog for PCAT18 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for PCAT18 Gene

ENSEMBL:
Gene Tree for PCAT18 (if available)
TreeFam:
Gene Tree for PCAT18 (if available)

Paralogs for PCAT18 Gene

No data available for Paralogs for PCAT18 Gene

Variants for PCAT18 Gene

Additional dbSNP identifiers (rs#s) for PCAT18 Gene

Structural Variations from Database of Genomic Variants (DGV) for PCAT18 Gene

Variant ID Type Subtype PubMed ID
esv2761995 CNV loss 21179565

Additional Variant Information for PCAT18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PCAT18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for PCAT18 Gene

Disorders for PCAT18 Gene

MalaCards: The human disease database

(2) MalaCards diseases for PCAT18 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
prostate cancer
  • prostate cancer, somatic
renal cell carcinoma, nonpapillary
  • rcc
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with PCAT18: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PCAT18 Gene

Publications for PCAT18 Gene

  1. Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer. (PMID: 24519926) Crea F … Helgason CD (Oncotarget 2014) 2 3
  2. lncRNA PCAT18 inhibits proliferation, migration and invasion of gastric cancer cells through miR-135b suppression to promote CLDN11 expression. (PMID: 32119960) Zhang XZ … Liu HC (Life sciences 2020) 3
  3. Tissue-Specific Down-Regulation of the Long Non-Coding RNAs PCAT18 and LINC01133 in Gastric Cancer Development. (PMID: 30518158) Foroughi K … Manoochehri M (International journal of molecular sciences 2018) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
  5. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3

Products for PCAT18 Gene

Sources for PCAT18 Gene