Aliases for PBX2 Gene
External Ids for PBX2 Gene
Previous GeneCards Identifiers for PBX2 Gene
This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. [provided by RefSeq, Jul 2008]
GeneCards Summary for PBX2 Gene
PBX2 (PBX Homeobox 2) is a Protein Coding gene. Diseases associated with PBX2 include Duodenal Gastrinoma and Pancreatic Gastrinoma. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and chromatin binding. An important paralog of this gene is PBX3.
UniProtKB/Swiss-Prot for PBX2 Gene
Transcriptional activator that binds the sequence 5-ATCAATCAA-3. Activates transcription of PF4 in complex with MEIS1.