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Aliases for PBDC1 Gene

Aliases for PBDC1 Gene

  • Polysaccharide Biosynthesis Domain Containing 1 2 3 5
  • Polysaccharide Biosynthesis Domain-Containing Protein 1 3 4
  • CXorf26 3 4
  • Chromosome X Open Reading Frame 26 2
  • UPF0368 Protein Cxorf26 3
  • Protein PBDC1 3

External Ids for PBDC1 Gene

Previous HGNC Symbols for PBDC1 Gene

  • CXorf26

Previous GeneCards Identifiers for PBDC1 Gene

  • GC0XP075398
  • GC0XP075403
  • GC0XP075409

Summaries for PBDC1 Gene

GeneCards Summary for PBDC1 Gene

PBDC1 (Polysaccharide Biosynthesis Domain Containing 1) is a Protein Coding gene.

Additional gene information for PBDC1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PBDC1 Gene

Genomics for PBDC1 Gene

GeneHancer (GH) Regulatory Elements for PBDC1 Gene

Promoters and enhancers for PBDC1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ076171 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 656.7 +0.3 340 3.1 PKNOX1 SIN3A DMAP1 YY1 POLR2B GLIS2 FOS SP3 YY2 REST PBDC1 GC0XP076173 ZDHHC15 LOC100216356
GH0XJ076147 Enhancer 1.2 Ensembl ENCODE dbSUPER 5.6 -23.2 -23173 5.3 PKNOX1 ATF1 ZSCAN4 ZNF335 ZNF366 ATF7 ZEB2 ZNF585B GLIS1 IKZF1 PIR52738 ZDHHC15 TTC3P1 PBDC1 ENSG00000232186 MAGEE1 GC0XP076095
GH0XJ076182 Enhancer 0.7 ENCODE 5.8 +11.1 11050 3.7 FOXA2 SAP130 ZBTB21 CEBPG FEZF1 ZNF213 PRDM10 FOXA3 HLF ZNF10 PBDC1 ZDHHC15 LOC100216356
GH0XJ076427 Promoter/Enhancer 1.1 Ensembl ENCODE 3.3 +255.1 255110 1.9 SAP130 NRF1 ZNF48 ZNF335 ZFHX2 POLR2A PRDM10 ZFX EGR2 MAGEE1 ZDHHC15 TTC3P1 PBDC1 GC0XP076431
GH0XJ077046 Enhancer 0.5 Ensembl 3.4 +873.5 873472 0.4 ZNF335 KLF1 GATA3 FOXA1 ATP7A PBDC1 GC0XP077067 MIR325HG
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PBDC1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for PBDC1 Gene

Genomic Locations for PBDC1 Gene
5,382 bases
Plus strand
5,269 bases
Plus strand

Genomic View for PBDC1 Gene

Genes around PBDC1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PBDC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PBDC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PBDC1 Gene

Proteins for PBDC1 Gene

  • Protein details for PBDC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein PBDC1
    Protein Accession:

    Protein attributes for PBDC1 Gene

    233 amino acids
    Molecular mass:
    26057 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PBDC1 Gene

Post-translational modifications for PBDC1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PBDC1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PBDC1 Gene

Domains & Families for PBDC1 Gene

Gene Families for PBDC1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for PBDC1 Gene

Suggested Antigen Peptide Sequences for PBDC1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the PBDC1 family.
  • Belongs to the PBDC1 family.
genes like me logo Genes that share domains with PBDC1: view

Function for PBDC1 Gene

Phenotypes From GWAS Catalog for PBDC1 Gene

Gene Ontology (GO) - Molecular Function for PBDC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with PBDC1: view
genes like me logo Genes that share phenotypes with PBDC1: view

Animal Model Products

CRISPR Products

miRNA for PBDC1 Gene

miRTarBase miRNAs that target PBDC1

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PBDC1

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PBDC1 Gene

Localization for PBDC1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PBDC1 gene
Compartment Confidence
nucleus 3
cytosol 3
mitochondrion 2
extracellular 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for PBDC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with PBDC1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for PBDC1 Gene

Pathways & Interactions for PBDC1 Gene

SuperPathways for PBDC1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for PBDC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with PBDC1: view

No data available for Pathways by source and SIGNOR curated interactions for PBDC1 Gene

Drugs & Compounds for PBDC1 Gene

No Compound Related Data Available

Transcripts for PBDC1 Gene

mRNA/cDNA for PBDC1 Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(123) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PBDC1 Gene

Polysaccharide biosynthesis domain containing 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PBDC1

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for PBDC1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6
SP1: - -
SP2: - - - -
SP3: -
SP4: -

Relevant External Links for PBDC1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PBDC1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PBDC1 Gene

Protein differential expression in normal tissues from HIPED for PBDC1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PBDC1 Gene

Protein tissue co-expression partners for PBDC1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PBDC1 Gene:


SOURCE GeneReport for Unigene cluster for PBDC1 Gene:


Evidence on tissue expression from TISSUES for PBDC1 Gene

  • Liver(4.4)
genes like me logo Genes that share expression patterns with PBDC1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PBDC1 Gene

Orthologs for PBDC1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for PBDC1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CXORF26 34
  • 100 (a)
LOC473674 33
  • 99.51 (n)
(Canis familiaris)
Mammalia PBDC1 33
  • 89.12 (n)
-- 34
  • 84 (a)
-- 34
  • 81 (a)
(Bos Taurus)
Mammalia PBDC1 34 33
  • 87.43 (n)
(Rattus norvegicus)
Mammalia Pbdc1 33
  • 87.18 (n)
(Mus musculus)
Mammalia Pbdc1 16 34 33
  • 85.3 (n)
(Monodelphis domestica)
Mammalia PBDC1 34
  • 85 (a)
(Ornithorhynchus anatinus)
Mammalia PBDC1 34
  • 73 (a)
(Gallus gallus)
Aves PBDC1 34
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia pbdc1 33
  • 66.44 (n)
Str.10635 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.22768 33
(Danio rerio)
Actinopterygii pbdc1 34 33
  • 68.52 (n)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9565 33
fruit fly
(Drosophila melanogaster)
Insecta CG7519 34 33
  • 54.25 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007575 33
  • 52 (n)
(Caenorhabditis elegans)
Secernentea Y54E5A.5 34 33
  • 51.54 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C16159g 33
  • 51.38 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YPL225W 33
  • 51.23 (n)
-- 34
  • 42 (a)
-- 36
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFL129W 33
  • 50.13 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPBC3E7.07c 33
  • 50.12 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU09442 33
  • 49.75 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 48 (a)
Cin.1022 33
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.1022 33
Species where no ortholog for PBDC1 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PBDC1 Gene

Gene Tree for PBDC1 (if available)
Gene Tree for PBDC1 (if available)
Evolutionary constrained regions (ECRs) for PBDC1: view image

Paralogs for PBDC1 Gene

No data available for Paralogs for PBDC1 Gene

Variants for PBDC1 Gene

Sequence variations from dbSNP and Humsavar for PBDC1 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1002272324 -- 76,174,794(+) C/T intron_variant
rs1002404383 -- 76,175,234(+) G/A intron_variant
rs1003687312 -- 76,176,740(+) T/C intron_variant
rs1004180213 -- 76,174,898(+) T/G coding_sequence_variant, missense_variant
rs1004289685 -- 76,175,791(+) T/C intron_variant

Variation tolerance for PBDC1 Gene

Residual Variation Intolerance Score: 54% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.25; 5.59% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PBDC1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for PBDC1 Gene

Disorders for PBDC1 Gene

Additional Disease Information for PBDC1

No disorders were found for PBDC1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PBDC1 Gene

Publications for PBDC1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang QH … Chen Z (Genome research 2000) 2 3 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling. (PMID: 29128334) Malty RH … Babu M (Cell systems 2017) 3 58
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58

Products for PBDC1 Gene

Sources for PBDC1 Gene

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