Aliases for PATL1 Gene
External Ids for PATL1 Gene
Previous GeneCards Identifiers for PATL1 Gene
GeneCards Summary for PATL1 Gene
PATL1 (PAT1 Homolog 1, Processing Body MRNA Decay Factor) is a Protein Coding gene. Diseases associated with PATL1 include Hermansky-Pudlak Syndrome 7 and Hepatitis C Virus. Among its related pathways are Gene Expression and Deadenylation-dependent mRNA decay. Gene Ontology (GO) annotations related to this gene include poly(U) RNA binding. An important paralog of this gene is PATL2.
UniProtKB/Swiss-Prot Summary for PATL1 Gene
RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).