Aliases for PARP8 Gene
External Ids for PARP8 Gene
Previous GeneCards Identifiers for PARP8 Gene
GeneCards Summary for PARP8 Gene
PARP8 (Poly(ADP-Ribose) Polymerase Family Member 8) is a Protein Coding gene. Diseases associated with PARP8 include Epileptic Encephalopathy, Early Infantile, 24. Among its related pathways are Metabolism of water-soluble vitamins and cofactors and Metabolism. Gene Ontology (GO) annotations related to this gene include NAD+ ADP-ribosyltransferase activity. An important paralog of this gene is PARP6.
UniProtKB/Swiss-Prot Summary for PARP8 Gene
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
Poly (ADP-ribose) polymerase (PARP) catalyzes the post-translational modification of proteins by the addition of multiple ADP-ribose moieties. PARP transfers ADP-ribose from nicotinamide dinucleotide (NAD) to Glu/Asp residues on the substrate protein.