Aliases for PARP11 Gene
External Ids for PARP11 Gene
Previous HGNC Symbols for PARP11 Gene
Previous GeneCards Identifiers for PARP11 Gene
GeneCards Summary for PARP11 Gene
PARP11 (Poly(ADP-Ribose) Polymerase Family Member 11) is a Protein Coding gene. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and UVA-Induced MAPK Signaling. Gene Ontology (GO) annotations related to this gene include NAD+ ADP-ribosyltransferase activity. An important paralog of this gene is PARP12.
UniProtKB/Swiss-Prot for PARP11 Gene
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins (PubMed:25043379, PubMed:25673562). Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis (By similarity).
Poly (ADP-ribose) polymerase (PARP) catalyzes the post-translational modification of proteins by the addition of multiple ADP-ribose moieties. PARP transfers ADP-ribose from nicotinamide dinucleotide (NAD) to Glu/Asp residues on the substrate protein.