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PAQR8 (Progestin And AdipoQ Receptor Family Member 8) is a Protein Coding gene. Diseases associated with PAQR8 include Epilepsy With Generalized Tonic-Clonic Seizures and Epilepsy, Myoclonic Juvenile. Gene Ontology (GO) annotations related to this gene include steroid hormone receptor activity and steroid binding. An important paralog of this gene is PAQR7.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003707 | steroid hormone receptor activity | IBA | 21873635 |
GO:0005496 | steroid binding | IBA | 21873635 |
GO:0008289 | lipid binding | IEA | -- |
GO:0038023 | signaling receptor activity | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005794 | Golgi apparatus | IDA | -- |
GO:0005886 | plasma membrane | IBA,IDA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
Symbol | External ID(s) | Details |
---|---|---|
EHHADH | ||
LEPROTL1 | ||
MPP1 | ||
ABCF1 | ||
ABCF2-H2BE1 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007275 | multicellular organism development | IEA | -- |
GO:0030154 | cell differentiation | IEA | -- |
GO:0043401 | steroid hormone mediated signaling pathway | IEA | -- |
GO:0048477 | oogenesis | IEA | -- |
GO:0048545 | response to steroid hormone | IBA | 21873635 |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 |
---|---|---|---|---|---|---|---|
SP1: | |||||||
SP2: | - | - |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | PAQR8 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | PAQR8 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | PAQR8 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Paqr8 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | PAQR8 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Paqr8 30 17 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | PAQR8 30 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | PAQR8 30 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | paqr8 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | mpr-A-prov 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | paqr8 30 31 |
|
OneToMany | |
PAQR8 (1 of 2) 31 |
|
OneToMany | |||
mprb 30 |
|
||||
Worm (Caenorhabditis elegans) |
Secernentea | K11C4.2 30 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv21698 | CNV | gain | 19812545 |
esv2763551 | CNV | loss | 21179565 |
esv3608994 | CNV | gain | 21293372 |
esv3608996 | CNV | gain | 21293372 |
nsv1025395 | CNV | gain | 25217958 |
nsv1027645 | CNV | gain | 25217958 |
nsv527443 | CNV | loss | 19592680 |
nsv950179 | CNV | duplication | 24416366 |
Disorder | Aliases | PubMed IDs |
---|---|---|
epilepsy with generalized tonic-clonic seizures |
|
|
epilepsy, myoclonic juvenile |
|
|