Aliases for PAQR8 Gene
External Ids for PAQR8 Gene
Previous HGNC Symbols for PAQR8 Gene
Previous GeneCards Identifiers for PAQR8 Gene
GeneCards Summary for PAQR8 Gene
PAQR8 (Progestin And AdipoQ Receptor Family Member 8) is a Protein Coding gene. Diseases associated with PAQR8 include Epilepsy With Generalized Tonic-Clonic Seizures and Epilepsy, Myoclonic Juvenile. Gene Ontology (GO) annotations related to this gene include steroid hormone receptor activity and steroid binding. An important paralog of this gene is PAQR7.
UniProtKB/Swiss-Prot Summary for PAQR8 Gene
Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870).