Aliases for PANK3 Gene
External Ids for PANK3 Gene
Previous GeneCards Identifiers for PANK3 Gene
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver. [provided by RefSeq, Jul 2008]
GeneCards Summary for PANK3 Gene
PANK3 (Pantothenate Kinase 3) is a Protein Coding gene. Diseases associated with PANK3 include Neurodegeneration With Brain Iron Accumulation 1 and Neurodegeneration With Brain Iron Accumulation. Among its related pathways are Pantothenate and CoA biosynthesis and Metabolism of water-soluble vitamins and cofactors. Gene Ontology (GO) annotations related to this gene include pantothenate kinase activity. An important paralog of this gene is PANK2.
UniProtKB/Swiss-Prot Summary for PANK3 Gene
Plays a role in the physiological regulation of coenzyme A (CoA) levels.