External Ids for PALM Gene
Previous GeneCards Identifiers for PALM Gene
This gene encodes a member of the paralemmin protein family. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for PALM Gene
PALM (Paralemmin) is a Protein Coding gene. Diseases associated with PALM include Waardenburg Syndrome, Type 2B and Pettigrew Syndrome. Gene Ontology (GO) annotations related to this gene include D3 dopamine receptor binding. An important paralog of this gene is PALMD.
UniProtKB/Swiss-Prot Summary for PALM Gene
Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner.