This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. T... See more...

Aliases for PAK6 Gene

Aliases for PAK6 Gene

  • P21 (RAC1) Activated Kinase 6 2 3 5
  • P21 Protein (Cdc42/Rac)-Activated Kinase 6 2 3
  • Serine/Threonine-Protein Kinase PAK 6 3 4
  • P21(CDKN1A)-Activated Kinase 6 2 3
  • EC 2.7.11.1 4 52
  • PAK5 3 4
  • P21-Activated Kinase 6 4
  • EC 2.7.11 52
  • PAK-5 4
  • PAK-6 4

External Ids for PAK6 Gene

Previous GeneCards Identifiers for PAK6 Gene

  • GC15P035899
  • GC15P033427
  • GC15P038111
  • GC15P038248
  • GC15P038319
  • GC15P040509
  • GC15P017352

Summaries for PAK6 Gene

Entrez Gene Summary for PAK6 Gene

  • This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

GeneCards Summary for PAK6 Gene

PAK6 (P21 (RAC1) Activated Kinase 6) is a Protein Coding gene. Among its related pathways are Signaling by Robo receptor and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is PAK5.

UniProtKB/Swiss-Prot Summary for PAK6 Gene

  • Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.

Gene Wiki entry for PAK6 Gene

Additional gene information for PAK6 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PAK6 Gene

Genomics for PAK6 Gene

GeneHancer (GH) Regulatory Elements for PAK6 Gene

Promoters and enhancers for PAK6 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J040238 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 500.4 +22.6 22588 3.2 EP300 FOS ZIC2 ZBTB26 REST RFX1 CTBP1 ATF2 POLR2A OSR2 PAK6 RAD51-AS1 SRP14-AS1 ENSG00000279537 lnc-BUB1B-2 ENSG00000260648 BUB1B-PAK6
GH15J040251 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE dbSUPER 500.3 +35.1 35073 2.2 USF1 GABPA EZH2 POLR2A PHF8 GABPB1 EGR2 BACH1 SUZ12 LARP7 C15orf56 PAK6 ENSG00000279537 lnc-BUB1B-2 BUB1B-PAK6
GH15J040248 Promoter/Enhancer 1.2 EPDnew Ensembl dbSUPER 505.1 +32.1 32146 2.1 RUNX1 CTBP1 RBM25 NFIC REST BCOR GATA3 FOXA1 NR2F1 RCOR1 PAK6 C15orf56 ENSG00000279537 lnc-BUB1B-2 BUB1B-PAK6
GH15J040218 Enhancer 0.6 ENCODE 500.7 -0.1 -63 0.2 CTCF REST RAD21 TRIM22 TEAD1 SMC3 ZNF384 PBX2 ELF1 ZNF654 BUB1B-PAK6 PAK6 BUB1B piR-61945-154
GH15J040217 Enhancer 0.6 ENCODE 500.7 +0.1 57 0 CTCF REST TRIM22 TEAD1 SMC3 ZNF384 ELF1 ZNF654 RAD21 RFX5 BUB1B-PAK6 PAK6 BUB1B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PAK6 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PAK6

Top Transcription factor binding sites by QIAGEN in the PAK6 gene promoter:
  • AREB6
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • Meis-1
  • NF-1
  • STAT3

Genomic Locations for PAK6 Gene

Genomic Locations for PAK6 Gene
chr15:40,217,428-40,277,487
(GRCh38/hg38)
Size:
60,060 bases
Orientation:
Plus strand
chr15:40,509,629-40,569,688
(GRCh37/hg19)
Size:
60,060 bases
Orientation:
Plus strand

Genomic View for PAK6 Gene

Genes around PAK6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PAK6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PAK6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PAK6 Gene

Proteins for PAK6 Gene

  • Protein details for PAK6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NQU5-PAK6_HUMAN
    Recommended name:
    Serine/threonine-protein kinase PAK 6
    Protein Accession:
    Q9NQU5
    Secondary Accessions:
    • A8K2G2
    • B3KYB0
    • G5E9R2

    Protein attributes for PAK6 Gene

    Size:
    681 amino acids
    Molecular mass:
    74869 Da
    Quaternary structure:
    • Interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1 (By similarity). Interacts with the androgen receptor AR and the estrogen receptor ESR1. Interacts with IQGAP1 and PPM1B.

    Three dimensional structures from OCA and Proteopedia for PAK6 Gene

    Alternative splice isoforms for PAK6 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PAK6 Gene

Selected DME Specific Peptides for PAK6 Gene

Q9NQU5:
  • EVDIWSLG
  • DFGFCAQ
  • MDLRKQQRRELLFNEVVIMRDY
  • KIGEGSTG
  • AQELLDHP
  • AQSLGPA
  • WMAPEVI
  • VPKRKSLVGTPYWMAPEVISR
  • GTPYWMAPE
  • QGVIHRDIKSDSILL
  • EEQIATVC

Post-translational modifications for PAK6 Gene

  • Autophosphorylated. Phosphorylated by MAP2K6//MAPKK6, leading to PAK6 activation.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Abcam antibodies for PAK6
  • Boster Bio Antibodies for PAK6

Domains & Families for PAK6 Gene

Gene Families for PAK6 Gene

IUPHAR :
Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for PAK6 Gene

Blocks:
  • PAK-box/P21-Rho-binding
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PAK6 Gene

GenScript: Design optimal peptide antigens:
  • cDNA, FLJ79466, highly similar to Serine/threonine-protein kinase PAK 6 (EC2.7.11.1) (A8K2G2_HUMAN)
  • p21-activated kinase 6 (PAK6_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9NQU5

UniProtKB/Swiss-Prot:

PAK6_HUMAN :
  • Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Family:
  • Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
genes like me logo Genes that share domains with PAK6: view

Function for PAK6 Gene

Molecular function for PAK6 Gene

UniProtKB/Swiss-Prot Function:
Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.1;.

Enzyme Numbers (IUBMB) for PAK6 Gene

Phenotypes From GWAS Catalog for PAK6 Gene

Gene Ontology (GO) - Molecular Function for PAK6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity IEA --
GO:0004674 protein serine/threonine kinase activity IBA 21873635
GO:0005515 protein binding IPI 24510904
GO:0005524 ATP binding IEA --
GO:0016301 kinase activity IEA --
genes like me logo Genes that share ontologies with PAK6: view
genes like me logo Genes that share phenotypes with PAK6: view

Animal Models for PAK6 Gene

MGI Knock Outs for PAK6:
  • Pak6 Pak6<tm1Amin>

Animal Model Products

  • Taconic Biosciences Mouse Models for PAK6

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PAK6

Clone Products

  • Addgene plasmids for PAK6

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PAK6 Gene

Localization for PAK6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PAK6 Gene

Cytoplasm. Nucleus. Note=Cotranslocates into nucleus with AR in response to androgen induction.

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
  • Nucleoli fibrillar center (2)
  • Cell Junctions (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for PAK6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001650 fibrillar center IDA --
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IBA 21873635
GO:0030054 cell junction IDA --
genes like me logo Genes that share ontologies with PAK6: view

No data available for Subcellular locations from COMPARTMENTS for PAK6 Gene

Pathways & Interactions for PAK6 Gene

PathCards logo

SuperPathways for PAK6 Gene

SuperPathway Contained pathways
1 Integrin Pathway
.67
.67
.56
.38
2 Focal Adhesion
3 fMLP Pathway
.44
.39
.31
4 ERK Signaling
.61
.61
.58
5 GPCR Pathway
.73
.73
.62
genes like me logo Genes that share pathways with PAK6: view

Pathways by source for PAK6 Gene

1 GeneGo (Thomson Reuters) pathway for PAK6 Gene
  • Transcription Androgen Receptor nuclear signaling
31 Qiagen pathways for PAK6 Gene
  • Actin Nucleation and Branching
  • Actin-Based Motility by Rho Family GTPases
  • Agrin Interactions at Neuromuscular Junction
  • Angiopoietin-TIE2 Signaling
  • CCR3 Pathway in Eosinophils
1 Cell Signaling Technology pathway for PAK6 Gene

SIGNOR curated interactions for PAK6 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for PAK6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated TAS 20070256
GO:0006468 protein phosphorylation IEA --
GO:0006915 apoptotic process TAS 20070256
GO:0007010 cytoskeleton organization TAS 20070256
GO:0007612 learning IEA --
genes like me logo Genes that share ontologies with PAK6: view

Drugs & Compounds for PAK6 Gene

(5) Drugs for PAK6 Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
fostamatinib Approved, Investigational Pharma Target, inhibitor Kinase Inhibitors 0
Guanosine triphosphate Experimental Pharma 0

(1) Additional Compounds for PAK6 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with PAK6: view

Transcripts for PAK6 Gene

mRNA/cDNA for PAK6 Gene

3 REFSEQ mRNAs :
8 NCBI additional mRNA sequence :
20 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PAK6

Clone Products

  • Addgene plasmids for PAK6

Alternative Splicing Database (ASD) splice patterns (SP) for PAK6 Gene

No ASD Table

Relevant External Links for PAK6 Gene

GeneLoc Exon Structure for
PAK6

Expression for PAK6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PAK6 Gene

mRNA differential expression in normal tissues according to GTEx for PAK6 Gene

This gene is overexpressed in Brain - Anterior cingulate cortex (BA24) (x5.2), Brain - Cortex (x5.1), and Brain - Frontal Cortex (BA9) (x4.1).

Protein differential expression in normal tissues from HIPED for PAK6 Gene

This gene is overexpressed in Lung (61.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PAK6 Gene



Protein tissue co-expression partners for PAK6 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PAK6

SOURCE GeneReport for Unigene cluster for PAK6 Gene:

Hs.732375

mRNA Expression by UniProt/SwissProt for PAK6 Gene:

Q9NQU5-PAK6_HUMAN
Tissue specificity: Selectively expressed in brain and testis, with lower levels in multiple tissues including prostate and breast.

Evidence on tissue expression from TISSUES for PAK6 Gene

  • Nervous system(4.9)
genes like me logo Genes that share expression patterns with PAK6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for PAK6 Gene

Orthologs for PAK6 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for PAK6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PAK6 31 30
  • 99.56 (n)
OneToOne
dog
(Canis familiaris)
Mammalia PAK6 31 30
  • 92.02 (n)
OneToOne
cow
(Bos Taurus)
Mammalia PAK6 31 30
  • 91.73 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Pak6 17 31 30
  • 88.79 (n)
rat
(Rattus norvegicus)
Mammalia Pak6 30
  • 87.86 (n)
oppossum
(Monodelphis domestica)
Mammalia PAK6 31
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 49 (a)
OneToMany
-- 31
  • 45 (a)
OneToMany
-- 31
  • 35 (a)
OneToMany
chicken
(Gallus gallus)
Aves PAK6 31 30
  • 75.09 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia PAK6 31
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia pak6 30
  • 63.55 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100536197 30
  • 68.83 (n)
pak6b 31
  • 57 (a)
OneToMany
PAK6 (1 of 2) 31
  • 54 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta mbt 31 32
  • 46 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea C45B11.1a 32
  • 45 (a)
C45B11.1b 32
  • 45 (a)
pak-2 31
  • 44 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes STE20 31
  • 21 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10829 31
  • 40 (a)
OneToMany
Species where no ortholog for PAK6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PAK6 Gene

ENSEMBL:
Gene Tree for PAK6 (if available)
TreeFam:
Gene Tree for PAK6 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for PAK6: view image

Paralogs for PAK6 Gene

(13) SIMAP similar genes for PAK6 Gene using alignment to 12 proteins:

  • PAK6_HUMAN
  • G5E9R2_HUMAN
  • H0YK38_HUMAN
  • H0YK74_HUMAN
  • H0YK91_HUMAN
  • H0YKB6_HUMAN
  • H0YL02_HUMAN
  • H0YL16_HUMAN
  • H0YL47_HUMAN
  • H0YLZ9_HUMAN
  • H0YM99_HUMAN
  • H0YMS4_HUMAN
genes like me logo Genes that share paralogs with PAK6: view

Variants for PAK6 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PAK6 Gene

SNP ID Clinical significance and condition Chr 15 pos Variation AA Info Type
769410 Benign: not provided 40,266,259(+) C/A MISSENSE_VARIANT
782719 Benign: not provided 40,266,209(+) G/A MISSENSE_VARIANT
789069 Benign: not provided 40,266,206(+) A/G MISSENSE_VARIANT
789070 Benign: not provided 40,266,230(+) G/A MISSENSE_VARIANT
rs1407997977 Uncertain Significance: Keratoconus 40,274,253(+) C/A MISSENSE_VARIANT,INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for PAK6 Gene

Structural Variations from Database of Genomic Variants (DGV) for PAK6 Gene

Variant ID Type Subtype PubMed ID
dgv731e212 CNV loss 25503493
esv34145 CNV loss 18971310
esv3581642 CNV loss 25503493
esv3581647 CNV loss 25503493
esv3581650 CNV loss 25503493
nsv457118 CNV loss 19166990
nsv471240 CNV loss 18288195
nsv510660 CNV deletion 20534489
nsv517541 CNV loss 19592680
nsv569227 CNV loss 21841781
nsv952611 CNV deletion 24416366

Variation tolerance for PAK6 Gene

Residual Variation Intolerance Score: 65.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.30; 76.53% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PAK6 Gene

Human Gene Mutation Database (HGMD)
PAK6
SNPedia medical, phenotypic, and genealogical associations of SNPs for
PAK6

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PAK6 Gene

Disorders for PAK6 Gene

Additional Disease Information for PAK6

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for PAK6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PAK6 Gene

Publications for PAK6 Gene

  1. Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6. (PMID: 11278661) Yang F … Sun Z (The Journal of biological chemistry 2001) 2 3 4 23 54
  2. Inhibition of p21-activated kinase 6 (PAK6) increases radiosensitivity of prostate cancer cells. (PMID: 20054820) Zhang M … Chakravarti A (The Prostate 2010) 3 4 23 54
  3. Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase. (PMID: 15550393) Kaur R … Lu ML (The Journal of biological chemistry 2005) 3 4 23 54
  4. Mechanism of p21-activated kinase 6-mediated inhibition of androgen receptor signaling. (PMID: 14573606) Schrantz N … Bokoch GM (The Journal of biological chemistry 2004) 3 4 23 54
  5. AR and ER interaction with a p21-activated kinase (PAK6). (PMID: 11773441) Lee SR … Balk SP (Molecular endocrinology (Baltimore, Md.) 2002) 3 4 23 54

Products for PAK6 Gene

Sources for PAK6 Gene