Aliases for PADI6 Gene
External Ids for PADI6 Gene
Previous GeneCards Identifiers for PADI6 Gene
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development. [provided by RefSeq, Sep 2012]
GeneCards Summary for PADI6 Gene
PADI6 (Peptidyl Arginine Deiminase 6) is a Protein Coding gene. Diseases associated with PADI6 include Preimplantation Embryonic Lethality 2. Among its related pathways are Chromatin organization and protein citrullination. Gene Ontology (GO) annotations related to this gene include calcium ion binding and protein-arginine deiminase activity. An important paralog of this gene is PADI4.
UniProtKB/Swiss-Prot for PADI6 Gene
Catalyzes the deimination of arginine residues of proteins (By similarity). May be involved in cytoskeletal reorganization in the egg and early embryo (PubMed:27545678).